دورية أكاديمية

Blister formation in acute compartment syndrome: Unraveling the underlying predictors.

التفاصيل البيبلوغرافية
العنوان: Blister formation in acute compartment syndrome: Unraveling the underlying predictors.
المؤلفون: Long Y; Department of Orthopaedic Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, P.R. China.; Orthopaedic Research Institute of Hebei Province, Shijiazhuang, Hebei, P.R. China.; The Third Department of Orthopedics, Baoding First Central Hospital, Hebei, P.R. China., Yang S; Department of Orthopaedic Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, P.R. China.; Orthopaedic Research Institute of Hebei Province, Shijiazhuang, Hebei, P.R. China., Guo J; Department of Orthopaedic Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, P.R. China.; Orthopaedic Research Institute of Hebei Province, Shijiazhuang, Hebei, P.R. China.; Department of Joint Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, China., Hou Z; Department of Orthopaedic Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, P.R. China.; Orthopaedic Research Institute of Hebei Province, Shijiazhuang, Hebei, P.R. China.; NHC Key Laboratory of Intelligent Orthopaedic Equipment (The Third Hospital of Hebei Medical University), Shijiazhuang, Hebei, P.R. China.
المصدر: Medicine [Medicine (Baltimore)] 2024 May 17; Vol. 103 (20), pp. e38191.
نوع المنشور: Journal Article; Observational Study
اللغة: English
بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 2985248R Publication Model: Print Cited Medium: Internet ISSN: 1536-5964 (Electronic) Linking ISSN: 00257974 NLM ISO Abbreviation: Medicine (Baltimore) Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Hagerstown, Md : Lippincott Williams & Wilkins
مواضيع طبية MeSH: Blister*/etiology , Blister*/epidemiology , Compartment Syndromes*/etiology , Compartment Syndromes*/epidemiology, Humans ; Male ; Female ; Middle Aged ; Risk Factors ; Aged ; Adult ; Retrospective Studies ; Incidence ; Seasons ; ROC Curve ; Acute Disease ; Logistic Models
مستخلص: Blisters are a common complication of orthopedic trauma and can cause surgery delay and increase the risk of infection. This study aims to identify risk factors for blisters in patients with acute compartment syndrome (ACS). Our study collected data from 206 ACS patients admitted to 2 hospitals between November 2013 and January 2021. Patients were divided into 2 groups: the blister group (BG) and the control group (CG), based on the presence or absence of blisters. We conducted univariate analysis, logistic regression analysis, and receiver operating characteristic (ROC) curve analysis to identify any significant differences in demographics, comorbidities, and admission laboratory test results between the 2 groups. Our study found that the incidence of blisters in ACS patients was 21.8% (45 out of 206). Univariate analysis identified several factors that were significantly associated with blister formation. Logistic regression analysis showed that patients who developed ACS in the winter or spring (P = .007, OR = 2.690, 95% CI [1.308-5.534]), patients who received a referral (the process whereby patients are transferred between medical facilities for further evaluation and treatment attempts prior to admission to our hospital) (P = .009, OR = 4.235, 95% CI [1.432-12.527]), and patients with higher PLR (P = .036, OR = 1.005, 95% CI [1.000-1.009]) were independent risk factors for blisters. Additionally, a history of drinking (P = .039, OR = 0.027, 95% CI [0.046-0.927]) was found to be a protective factor for blister formation in these patients. Moreover, ROC curve analysis showed that a PLR value of 138 was the cutoff point for predicting the development of blisters in ACS patients. Our study identified seasonal factors (refer to these months like winter or spring), referral, and patients with higher PLR as independent risk factors, and a history of drinking as a protective factor for blister formation in ACS patients. These findings allow clinicians to individualize the evaluation of blister risk and perform early targeted therapies.
Competing Interests: The authors have no conflicts of interest to disclose.
(Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.)
References: Exp Biol Med (Maywood). 2016 Apr;241(8):783-99. (PMID: 27013544)
Front Oncol. 2022 Aug 10;12:945820. (PMID: 36033468)
Biomed Res Int. 2021 Mar 17;2021:7973123. (PMID: 33816631)
Surg Clin North Am. 1991 Apr;71(2):345-70. (PMID: 2003255)
Medicine (Baltimore). 2019 Jul;98(27):e16260. (PMID: 31277147)
Scand J Trauma Resusc Emerg Med. 2013 Jun 06;21:44. (PMID: 23742143)
Emerg Med Clin North Am. 2000 Feb;18(1):115-39, vi. (PMID: 10678162)
J Hand Surg Am. 2011 Mar;36(3):535-43. (PMID: 21371630)
Osteoporos Int. 2004 Jun;15(6):439-46. (PMID: 15205714)
Indian J Orthop. 2022 Feb 24;56(7):1181-1191. (PMID: 35813541)
Injury. 2020 Dec;51(12):2786-2792. (PMID: 33308645)
J Bone Miner Res. 2022 Aug;37(8):1527-1536. (PMID: 35689442)
Horm Mol Biol Clin Investig. 2020 May 08;42(2):113-122. (PMID: 32926606)
JBJS Rev. 2017 Dec;5(12):e1. (PMID: 29206684)
Mediators Inflamm. 2021 Jan 08;2021:8897440. (PMID: 33505222)
BMC Musculoskelet Disord. 2021 Sep 23;22(1):816. (PMID: 34556075)
Curr Rev Musculoskelet Med. 2012 Sep;5(3):206-13. (PMID: 22644598)
Am J Sports Med. 2007 Jan;35(1):93-102. (PMID: 17197574)
J Invest Dermatol. 1978 Sep;71(3):209-12. (PMID: 690485)
J Am Acad Orthop Surg. 2003 Nov-Dec;11(6):431-8. (PMID: 14686828)
J Bone Joint Surg Br. 2000 Mar;82(2):200-3. (PMID: 10755426)
J Orthop Trauma. 2008 Sep;22(8):581-7. (PMID: 18758292)
Ann Vasc Surg. 2022 Aug;84:305-313. (PMID: 35108554)
Int J Environ Res Public Health. 2022 Aug 02;19(15):. (PMID: 35954822)
J Orthop Trauma. 1995 Apr;9(2):171-6. (PMID: 7776039)
BMJ. 1993 Jun 5;306(6891):1506-9. (PMID: 8518677)
Injury. 2019 Oct;50(10):1656-1670. (PMID: 31558277)
Ulus Travma Acil Cerrahi Derg. 2022 Nov;28(11):1634-1640. (PMID: 36282165)
Injury. 2022 Feb;53(2):669-675. (PMID: 34742572)
West J Emerg Med. 2011 Feb;12(1):131-3. (PMID: 21691490)
J Womens Health. 1999 Jan-Feb;8(1):65-73. (PMID: 10094083)
تواريخ الأحداث: Date Created: 20240517 Date Completed: 20240517 Latest Revision: 20240709
رمز التحديث: 20240709
مُعرف محوري في PubMed: PMC11098220
DOI: 10.1097/MD.0000000000038191
PMID: 38758865
قاعدة البيانات: MEDLINE
الوصف
تدمد:1536-5964
DOI:10.1097/MD.0000000000038191