دورية أكاديمية
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Not feeling the heat? Effects of dietary protein on satiation and satiety in mice are not due to its impact on body temperature.

التفاصيل البيبلوغرافية
العنوان: Not feeling the heat? Effects of dietary protein on satiation and satiety in mice are not due to its impact on body temperature.
المؤلفون: Osorio M J; School of Biological Sciences, University of Aberdeen, AB24 2TZ, Scotland, UK; Institute of Neurobiology, University of Lübeck, 23562, Lübeck, Germany., Mitchell SE; School of Biological Sciences, University of Aberdeen, AB24 2TZ, Scotland, UK., Hambly C; School of Biological Sciences, University of Aberdeen, AB24 2TZ, Scotland, UK., Allison DB; Indiana University School of Public Health - Bloomington, Indiana, 47405, USA., Speakman JR; School of Biological Sciences, University of Aberdeen, AB24 2TZ, Scotland, UK; Shenzhen Key Laboratory of Metabolic Health, Center for Energy Metabolism and Reproduction, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, China; China Medical University, Shenyang, Liaoning, China. Electronic address: j.speakman@abdn.ac.uk.
المصدر: Appetite [Appetite] 2024 Sep 01; Vol. 200, pp. 107421. Date of Electronic Publication: 2024 May 15.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural
اللغة: English
بيانات الدورية: Publisher: Academic Press Country of Publication: England NLM ID: 8006808 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-8304 (Electronic) Linking ISSN: 01956663 NLM ISO Abbreviation: Appetite Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London, New York, Academic Press.
مواضيع طبية MeSH: Mice, Inbred C57BL* , Satiation* , Dietary Proteins*/administration & dosage , Dietary Proteins*/pharmacology , Body Temperature*, Animals ; Male ; Mice ; Feeding Behavior/physiology ; Eating/physiology ; Satiety Response
مستخلص: Dietary protein modulates food intake (FI) via unclear mechanism(s). One possibility is that higher protein leads to greater post-ingestive heat production (Specific dynamic action: SDA) leading to earlier meal termination (increased satiation), and inhibition of further intake (increased satiety). The influence of dietary protein on feeding behaviour in C57BL/6J mice was tested using an automated FI monitoring system (BioDAQ), simultaneous to body temperature (T b ). Total FI, inter meal intervals (IMI, satiety) and meal size (MS, satiation) were related to changes in T b after consuming low (5%, LP), moderate (15%, MP) and high (30%, HP) protein diets. Diets were tested over three conditions: 1) room temperature (RT, 21 ± 1 °C), 2) room temperature and running wheels (RTRW) and 3) low temperature (10 °C) and running wheels (LTRW). The differences between diets and conditions were also compared using mixed models. Mice housed at RT fed HP diet, reduced total FI compared with LP and MP due to earlier meal termination (satiation effect). FI was lowered in RTRW conditions with no differences between diets. FI significantly increased under LTRW conditions for all diets, with protein content leading to earlier meal termination (satiation) but not the intervals between feeding bouts (satiety). T b fell immediately after feeding in all conditions. Despite a reduction in total FI in mice fed HP, mediated via increased satiation, this effect was not linked to increased T b during meals. We conclude effects of dietary protein on intake are not mediated via SDA and T b .
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)
معلومات مُعتمدة: R01 AG043972 United States AG NIA NIH HHS
فهرسة مساهمة: Keywords: Body temperature; Dietary protein; Hunger; Satiation; Specific dynamic action
المشرفين على المادة: 0 (Dietary Proteins)
تواريخ الأحداث: Date Created: 20240517 Date Completed: 20240705 Latest Revision: 20240923
رمز التحديث: 20240924
DOI: 10.1016/j.appet.2024.107421
PMID: 38759755
قاعدة البيانات: MEDLINE
الوصف
تدمد:1095-8304
DOI:10.1016/j.appet.2024.107421