دورية أكاديمية
Clinicopathological and diagnostic imaging findings in a dog with neurocandidiasis.
| العنوان: | Clinicopathological and diagnostic imaging findings in a dog with neurocandidiasis. |
|---|---|
| المؤلفون: | Royaux E; Davies Veterinary Specialists part of Linnaeus Veterinary Limited, Hitchin, United Kingdom., Corbetta D; The Queen's Veterinary Hospital, University of Cambridge, Cambridge, United Kingdom., Czerwiñska M; Davies Veterinary Specialists part of Linnaeus Veterinary Limited, Hitchin, United Kingdom., Gosling F; Veterinary Pathology Group (VPG), Hitchin, United Kingdom., Genain MA; Cambridge Veterinary School, Veterinary Medicine, Cambridge, United Kingdom. |
| المصدر: | Journal of veterinary internal medicine [J Vet Intern Med] 2024 Jul-Aug; Vol. 38 (4), pp. 2362-2367. Date of Electronic Publication: 2024 May 20. |
| نوع المنشور: | Case Reports; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wiley Periodicals Country of Publication: United States NLM ID: 8708660 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1939-1676 (Electronic) Linking ISSN: 08916640 NLM ISO Abbreviation: J Vet Intern Med Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2010-> : Malden, MA : Wiley Periodicals Original Publication: Philadelphia : J.B. Lippincott Co., [c1987- |
| مواضيع طبية MeSH: | Dog Diseases*/diagnostic imaging , Dog Diseases*/pathology , Magnetic Resonance Imaging*/veterinary , Candidiasis*/veterinary , Candidiasis*/diagnostic imaging , Candidiasis*/pathology, Animals ; Dogs ; Brain/diagnostic imaging ; Brain/pathology ; Candida albicans/isolation & purification ; Male ; Central Nervous System Fungal Infections/veterinary ; Central Nervous System Fungal Infections/diagnostic imaging ; Central Nervous System Fungal Infections/pathology ; Central Nervous System Fungal Infections/drug therapy ; Female ; Antifungal Agents/therapeutic use |
| مستخلص: | Neurocandidiasis is systemic candidiasis with central nervous system involvement. This case report describes the clinical presentation, diagnostic test results, and histopathology of a dog with neurocandidiasis. A 3-year-old German shepherd dog was presented for a 3-day history of abnormal mentation, neck pain, and ataxia. Magnetic resonance imaging (MRI) scan of the brain revealed multifocal, small, round, intra-axial lesions within the forebrain. Examination of the cerebrospinal fluid revealed severe neutrophilic inflammation. Extensive testing for infectious diseases was negative. The dog was administered immunosuppressive doses of corticosteroids. The dog's clinical signs improved transiently but got worse 12 days after starting the treatment. Repeat MRI scan revealed multiple, intra-axial, target-like nodular lesions scattered throughout the brain parenchyma. In the temporal muscles, nodules were seen. Cytology of the fine needle aspirates of the nodules in the temporal muscles revealed a neutrophilic inflammation with hyalohyphomycosis. Postmortem examination was compatible with a severe systemic fungal infection. Candida albicans was isolated from the brain, kidney, and heart. (© 2024 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals LLC on behalf of American College of Veterinary Internal Medicine.) |
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| معلومات مُعتمدة: | Linnaeus Veterinary Limited supported the costs of the Open Access Publication Charges |
| فهرسة مساهمة: | Keywords: CSF analysis; fungal; microbiology; neuroanatomy and neuropathology; neuroimaging; neurology |
| المشرفين على المادة: | 0 (Antifungal Agents) |
| تواريخ الأحداث: | Date Created: 20240521 Date Completed: 20240718 Latest Revision: 20240720 |
| رمز التحديث: | 20240720 |
| مُعرف محوري في PubMed: | PMC11256180 |
| DOI: | 10.1111/jvim.17093 |
| PMID: | 38769641 |
| قاعدة البيانات: | MEDLINE |
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