دورية أكاديمية
Hyperemesis gravidarum theories dispelled by recent research: a paradigm change for better care and outcomes.
| العنوان: | Hyperemesis gravidarum theories dispelled by recent research: a paradigm change for better care and outcomes. |
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| المؤلفون: | Fejzo MS; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA. Electronic address: Marlena.Fejzo@med.usc.edu. |
| المصدر: | Trends in molecular medicine [Trends Mol Med] 2024 Jun; Vol. 30 (6), pp. 530-540. Date of Electronic Publication: 2024 May 22. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 100966035 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-499X (Electronic) Linking ISSN: 14714914 NLM ISO Abbreviation: Trends Mol Med Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Oxford, UK : Elsevier Science Ltd., c2001- |
| مواضيع طبية MeSH: | Hyperemesis Gravidarum*/therapy, Humans ; Pregnancy ; Female ; Animals |
| مستخلص: | Nausea and vomiting (NVP) affect most pregnant women. At the severe end of the clinical spectrum, hyperemesis gravidarum (HG) can be life-threatening. The condition is fraught with misconceptions that have slowed progress and left women undertreated. Herein, recent scientific advances are presented that dispel common myths associated with HG related to maternal/offspring outcomes, etiology, and evolution. There is now strong evidence that (i) HG is associated with poor outcomes, (ii) a common cause of NVP and HG has been identified, and (iii) NVP is likely a protective evolutionary mechanism that occurs throughout the animal kingdom but is no longer necessary for human survival. Therefore, it is encouraging that we are finally on the cusp of testing treatments that may put an end to unnecessary suffering. Competing Interests: Declaration of interests M.S.F. is Chief Scientific Officer, shareholder, and a paid consultant of Harmonia Healthcare and is a paid consultant for NGM Biosciences. M.S.F. is also a Board Member and Research Director for the Hyperemesis Education and Research Foundation and a Board Member for the Foundation for Women's Health. (Copyright © 2024 Elsevier Ltd. All rights reserved.) |
| فهرسة مساهمة: | Keywords: hyperemesis gravidarum; morning sickness; nausea; pregnancy; vomiting |
| تواريخ الأحداث: | Date Created: 20240523 Date Completed: 20240613 Latest Revision: 20240617 |
| رمز التحديث: | 20240617 |
| DOI: | 10.1016/j.molmed.2024.04.006 |
| PMID: | 38782680 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1471-499X |
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| DOI: | 10.1016/j.molmed.2024.04.006 |