دورية أكاديمية
Physiological and genomic signatures of war and displacement: A comprehensive literature review and future directions.
| العنوان: | Physiological and genomic signatures of war and displacement: A comprehensive literature review and future directions. |
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| المؤلفون: | Jankovic-Rankovic J; Department of Anthropology, University of South Carolina, Columbia, SC 29205, USA. Electronic address: jjankovic@sc.edu., Panter-Brick C; Department of Anthropology, Yale University, New Haven, CT 06520, USA; Jackson School of Global Affairs, Yale University, New Haven, CT 06520, USA. |
| المصدر: | Psychoneuroendocrinology [Psychoneuroendocrinology] 2024 Aug; Vol. 166, pp. 107084. Date of Electronic Publication: 2024 May 18. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Pergamon Press Country of Publication: England NLM ID: 7612148 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3360 (Electronic) Linking ISSN: 03064530 NLM ISO Abbreviation: Psychoneuroendocrinology Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Oxford, Elmsford, N. Y., Pergamon Press. |
| مواضيع طبية MeSH: | Refugees*/psychology , Genomics*/methods , Warfare*, Humans ; Biomarkers ; Europe ; Middle East ; Stress Disorders, Post-Traumatic/genetics |
| مستخلص: | There are now 108.4 million forcibly displaced people worldwide, many of whom endure adversities that result in trauma, toxic stress, and potentially, altered epigenetic development. This paper provides a comprehensive review of current literature on the biological signatures of war and forced migration among refugee populations. To consolidate evidence and identify key concerns and avenues for future research, we reviewed 36 publications and one article under review, published since 2000, most of which focused on refugees relocated in Europe and the Middle East. This body of work - including cross-sectional, observational, and experimental studies - reveals heterogenous findings regarding human biological responses to war-related adversities and their associations with health outcomes. We conclude with four main observations, regarding why genomic and physiological biomarkers are valuable, what study designs advance understanding of causality and health-promoting interventions, how to prepare for ethical challenges, and why theoretical frameworks and research procedures need more detailed consideration in scientific publications. Competing Interests: Declaration of Competing Interest The authors declare no conflict of interest. (Copyright © 2024 Elsevier Ltd. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Biomarker; Epigenetics; Genetics; Health; Physiology; Refugee |
| المشرفين على المادة: | 0 (Biomarkers) |
| تواريخ الأحداث: | Date Created: 20240524 Date Completed: 20240614 Latest Revision: 20240618 |
| رمز التحديث: | 20240619 |
| DOI: | 10.1016/j.psyneuen.2024.107084 |
| PMID: | 38788460 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1873-3360 |
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| DOI: | 10.1016/j.psyneuen.2024.107084 |