دورية أكاديمية
The Horse with Recurrent Fevers and Infections: Approach to Common Variable Immunodeficiency.
| العنوان: | The Horse with Recurrent Fevers and Infections: Approach to Common Variable Immunodeficiency. |
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| المؤلفون: | Mullen KR; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Anschutz Health Sciences Building, 1890 North Revere Court, Mailstop F600, Aurora, CO 80045, USA., Felippe MJB; Department of Clinical Sciences, Cornell University College of Veterinary Medicine, 930 Campus Road, Box 34, Ithaca, NY 14853, USA. Electronic address: mbf6@cornell.edu. |
| المصدر: | The Veterinary clinics of North America. Equine practice [Vet Clin North Am Equine Pract] 2024 Aug; Vol. 40 (2), pp. 179-188. Date of Electronic Publication: 2024 May 23. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: W.B. Saunders Country of Publication: United States NLM ID: 8511904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-4224 (Electronic) Linking ISSN: 07490739 NLM ISO Abbreviation: Vet Clin North Am Equine Pract Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Philadelphia : W.B. Saunders, c1985- |
| مواضيع طبية MeSH: | Common Variable Immunodeficiency*/veterinary , Common Variable Immunodeficiency*/diagnosis , Horse Diseases*/diagnosis, Animals ; Horses ; Fever/veterinary |
| مستخلص: | Equine common variable immunodeficiency (CVID) is a rare, late-onset, nonfamilial humoral deficiency characterized by B-cell depletion and/or dysfunction resulting in inadequate antibody production and predisposition to recurrent infections. Serum immunoglobulin concentration and peripheral blood lymphocyte immunophenotyping are required to diagnose and characterize CVID in horses. Early recognition of the disease by the equine practitioner is paramount to managing the quality of life for these patients, for whom specific treatment is not yet available and long-term prognosis remains poor. An approach to the diagnosis, identification of complicating factors, and management of horses with CVID are discussed. Competing Interests: Disclosure Dr M.J.B. Felippe is the head of the Equine Immunology Laboratory, a not-for-profit research laboratory that provides immunologic testing for horses with suspected immunodeficiencies. (Copyright © 2024 Elsevier Inc. All rights reserved.) |
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| معلومات مُعتمدة: | DP2 OD007216 United States OD NIH HHS |
| فهرسة مساهمة: | Keywords: Common variable immunodeficiency (CVID); Horse; Hypogammaglobulinemia; Primary immunodeficiency; Recurrent bacterial infections; Recurrent fevers |
| تواريخ الأحداث: | Date Created: 20240524 Date Completed: 20240704 Latest Revision: 20240706 |
| رمز التحديث: | 20240706 |
| مُعرف محوري في PubMed: | PMC11223947 |
| DOI: | 10.1016/j.cveq.2024.04.005 |
| PMID: | 38789347 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1558-4224 |
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| DOI: | 10.1016/j.cveq.2024.04.005 |