دورية أكاديمية
Salvianolic acid A alleviates H 2 O 2 -induced endothelial oxidative injury via miR-204-5p.
| العنوان: | Salvianolic acid A alleviates H |
|---|---|
| المؤلفون: | Qiao X; School of Life Science, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China., Cao S; School of Life Science, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China., Chen S; School of Life Science, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China., Guo Y; Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China., Chen N; School of Life Science, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China., Zheng Y; The 903rd Hospital of the People's Liberation Army, Hangzhou, Zhejiang, China. zhengying72@163.com., Jin B; School of Life Science, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China. jinbo@zcmu.edu.cn. |
| المصدر: | Scientific reports [Sci Rep] 2024 May 24; Vol. 14 (1), pp. 11931. Date of Electronic Publication: 2024 May 24. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: London : Nature Publishing Group, copyright 2011- |
| مواضيع طبية MeSH: | MicroRNAs*/genetics , MicroRNAs*/metabolism , Hydrogen Peroxide*/toxicity , Hydrogen Peroxide*/pharmacology , Human Umbilical Vein Endothelial Cells*/drug effects , Human Umbilical Vein Endothelial Cells*/metabolism , Oxidative Stress*/drug effects , Lactates*/pharmacology , Lactates*/metabolism , Apoptosis*/drug effects , Cell Survival*/drug effects, Humans ; Caffeic Acids/pharmacology ; Cell Proliferation/drug effects ; Reactive Oxygen Species/metabolism ; Autophagy/drug effects ; Cellular Senescence/drug effects ; Antioxidants/pharmacology ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein/genetics |
| مستخلص: | Oxidative stress induced endothelial dysfunction plays a particularly important role in promoting the development of cardiovascular diseases (CVDs). Salvianolic acid A (SalA) is a water-soluble component of traditional Chinese medicine Salvia miltiorrhiza Bunge with anti-oxidant potency. This study aims to explore the regulatory effect of SalA on oxidative injury using an in vitro model of H (© 2024. The Author(s).) |
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| معلومات مُعتمدة: | No.82304763 the Natural Science Foundation of China; No.82374071 the Natural Science Foundation of China; LY23H280006 the Natural Science Foundation of Zhejiang Province; 2022GJYY024 the Scientific Research Foundation of Zhejiang Chinese Medical University |
| المشرفين على المادة: | 0 (MicroRNAs) BBX060AN9V (Hydrogen Peroxide) 51622542XO (salvianolic acid A) 0 (Lactates) 0 (Caffeic Acids) 0 (Reactive Oxygen Species) 0 (Antioxidants) 0 (NLR Family, Pyrin Domain-Containing 3 Protein) |
| تواريخ الأحداث: | Date Created: 20240524 Date Completed: 20240524 Latest Revision: 20240611 |
| رمز التحديث: | 20240612 |
| مُعرف محوري في PubMed: | PMC11126572 |
| DOI: | 10.1038/s41598-024-62556-4 |
| PMID: | 38789509 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 2045-2322 |
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| DOI: | 10.1038/s41598-024-62556-4 |