دورية أكاديمية
Impact of the COVID-19 Pandemic on Hepatitis C Treatment Initiation in British Columbia, Canada: An Interrupted Time Series Study.
العنوان: | Impact of the COVID-19 Pandemic on Hepatitis C Treatment Initiation in British Columbia, Canada: An Interrupted Time Series Study. |
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المؤلفون: | Morrow RL; British Columbia Centre for Disease Control, Vancouver, BC V5Z 4R4, Canada.; School of Population and Public Health, University of British Columbia, Vancouver, BC V6T 1Z3, Canada., Binka M; British Columbia Centre for Disease Control, Vancouver, BC V5Z 4R4, Canada.; School of Population and Public Health, University of British Columbia, Vancouver, BC V6T 1Z3, Canada., Li J; British Columbia Centre for Disease Control, Vancouver, BC V5Z 4R4, Canada., Irvine M; British Columbia Centre for Disease Control, Vancouver, BC V5Z 4R4, Canada.; Faculty of Health Sciences, Simon Fraser University, Burnaby, BC V5A 1S6, Canada., Bartlett SR; British Columbia Centre for Disease Control, Vancouver, BC V5Z 4R4, Canada.; School of Population and Public Health, University of British Columbia, Vancouver, BC V6T 1Z3, Canada., Wong S; British Columbia Centre for Disease Control, Vancouver, BC V5Z 4R4, Canada., Jeong D; British Columbia Centre for Disease Control, Vancouver, BC V5Z 4R4, Canada.; School of Population and Public Health, University of British Columbia, Vancouver, BC V6T 1Z3, Canada., Makuza JD; British Columbia Centre for Disease Control, Vancouver, BC V5Z 4R4, Canada.; School of Population and Public Health, University of British Columbia, Vancouver, BC V6T 1Z3, Canada., Wong J; British Columbia Centre for Disease Control, Vancouver, BC V5Z 4R4, Canada.; School of Population and Public Health, University of British Columbia, Vancouver, BC V6T 1Z3, Canada., Yu A; British Columbia Centre for Disease Control, Vancouver, BC V5Z 4R4, Canada., Krajden M; British Columbia Centre for Disease Control, Vancouver, BC V5Z 4R4, Canada.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC V6T 1Z4, Canada., Janjua NZ; British Columbia Centre for Disease Control, Vancouver, BC V5Z 4R4, Canada.; School of Population and Public Health, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.; Centre for Health Evaluation and Outcome Sciences, St Paul's Hospital, Vancouver, BC V6Z 1Y6, Canada. |
المصدر: | Viruses [Viruses] 2024 Apr 23; Vol. 16 (5). Date of Electronic Publication: 2024 Apr 23. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915 (Electronic) Linking ISSN: 19994915 NLM ISO Abbreviation: Viruses Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: Basel, Switzerland : MDPI |
مواضيع طبية MeSH: | COVID-19*/epidemiology , Interrupted Time Series Analysis* , Hepatitis C*/epidemiology , Hepatitis C*/drug therapy , Antiviral Agents*/therapeutic use, Humans ; British Columbia/epidemiology ; Male ; Female ; Middle Aged ; Adult ; SARS-CoV-2 ; Substance Abuse, Intravenous/epidemiology ; Substance Abuse, Intravenous/complications ; Pandemics ; Aged ; Cohort Studies |
مستخلص: | We investigated the impacts of the COVID-19 pandemic on hepatitis C (HCV) treatment initiation, including by birth cohort and injection drug use status, in British Columbia (BC), Canada. Using population data from the BC COVID-19 Cohort, we conducted interrupted time series analyses, estimating changes in HCV treatment initiation following the introduction of pandemic-related policies in March 2020. The study included a pre-policy period (April 2018 to March 2020) and three follow-up periods (April to December 2020, January to December 2021, and January to December 2022). The level of HCV treatment initiation decreased by 26% in April 2020 (rate ratio 0.74, 95% confidence interval [CI] 0.60 to 0.91). Overall, no statistically significant difference in HCV treatment initiation occurred over the 2020 and 2021 post-policy periods, and an increase of 34.4% (95% CI 0.6 to 75.8) occurred in 2022 (equating to 321 additional people initiating treatment), relative to expectation. Decreases in HCV treatment initiation occurred in 2020 for people born between 1965 and 1974 (25.5%) and people who inject drugs (24.5%), relative to expectation. In summary, the pandemic was associated with short-term disruptions in HCV treatment initiation in BC, which were greater for people born 1965 to 1974 and people who inject drugs. |
References: | J Viral Hepat. 2022 Oct;29(10):908-918. (PMID: 35722739) Am J Prev Med. 2022 Oct;63(4):532-542. (PMID: 35738958) Infect Dis Ther. 2016 Dec;5(4):491-508. (PMID: 27783223) Liver Int. 2021 Dec;41(12):2849-2856. (PMID: 34592046) Can Liver J. 2022 Nov 07;5(4):493-506. (PMID: 38144411) Int J Drug Policy. 2018 May;55:31-39. (PMID: 29482150) J Viral Hepat. 2022 Mar;29(3):205-208. (PMID: 34820967) Viruses. 2021 Jul 07;13(7):. (PMID: 34372520) Drug Alcohol Depend. 2022 Mar 1;232:109263. (PMID: 35120807) BMC Infect Dis. 2017 Feb 21;17(1):162. (PMID: 28222681) Int J Drug Policy. 2022 Aug;106:103752. (PMID: 35653821) Clin Infect Dis. 2013 Aug;57 Suppl 2:S39-45. (PMID: 23884064) Clin Infect Dis. 2022 Aug 24;75(1):e955-e961. (PMID: 35234860) Can Commun Dis Rep. 2022 Nov 03;48(11-12):540-549. (PMID: 38222827) J Clin Epidemiol. 2015 Aug;68(8):950-6. (PMID: 25890805) Int J Drug Policy. 2021 Dec;98:103391. (PMID: 34343945) World J Hepatol. 2021 Jul 27;13(7):781-789. (PMID: 34367499) Can Liver J. 2022 Feb 4;5(1):96-100. (PMID: 35990789) Am J Gastroenterol. 2021 Aug 1;116(8):1738-1740. (PMID: 34587128) EBioMedicine. 2016 Oct;12:189-195. (PMID: 27596150) JHEP Rep. 2022 Sep;4(9):100531. (PMID: 35967191) Rev Esp Enferm Dig. 2023 Apr;115(4):175-180. (PMID: 35012318) Harm Reduct J. 2021 Nov 24;18(1):118. (PMID: 34819070) J Int AIDS Soc. 2020 Jul;23(7):e25583. (PMID: 32697423) |
معلومات مُعتمدة: | WI1-179874 Canada CIHR |
فهرسة مساهمة: | Keywords: British Columbia; COVID-19; cascade; hepatitis C; interrupted time series analysis |
المشرفين على المادة: | 0 (Antiviral Agents) |
تواريخ الأحداث: | Date Created: 20240525 Date Completed: 20240525 Latest Revision: 20240529 |
رمز التحديث: | 20240529 |
مُعرف محوري في PubMed: | PMC11125629 |
DOI: | 10.3390/v16050655 |
PMID: | 38793537 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1999-4915 |
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DOI: | 10.3390/v16050655 |