دورية أكاديمية
أعرض في EDS

Is routine histopathological analysis of hemorrhoidectomy specimens necessary? A systematic review and meta-analysis.

التفاصيل البيبلوغرافية
العنوان: Is routine histopathological analysis of hemorrhoidectomy specimens necessary? A systematic review and meta-analysis.
المؤلفون: Men V; Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand., Kaur D; Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand., Bahl P; Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand., Jin J; South Auckland Clinical Campus, The University of Auckland, Auckland, New Zealand., Hill A; South Auckland Clinical Campus, The University of Auckland, Auckland, New Zealand.
المصدر: World journal of surgery [World J Surg] 2024 Aug; Vol. 48 (8), pp. 1981-1989. Date of Electronic Publication: 2024 May 26.
نوع المنشور: Journal Article; Systematic Review; Meta-Analysis
اللغة: English
بيانات الدورية: Publisher: Springer International Country of Publication: United States NLM ID: 7704052 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-2323 (Electronic) Linking ISSN: 03642313 NLM ISO Abbreviation: World J Surg Subsets: MEDLINE
أسماء مطبوعة: Original Publication: New York, Springer International.
مواضيع طبية MeSH: Hemorrhoidectomy*/methods , Anus Neoplasms*/pathology , Anus Neoplasms*/surgery , Hemorrhoids*/surgery , Hemorrhoids*/pathology, Humans ; Prevalence ; Carcinoma in Situ/pathology ; Carcinoma in Situ/surgery ; Cost-Benefit Analysis
مستخلص: Background: Hemorrhoidectomy is a common procedure used to treat symptomatic hemorrhoids. However, the necessity and cost-effectiveness of routinely conducting histopathological analysis on excised tissue samples are uncertain.
Methods: A systematic review was conducted using MEDLINE and EMBASE up to December 2023 for studies assessing the histopathological outcomes of hemorrhoidectomy specimens. Meta-analysis was performed on articles with combinable results to determine the pooled proportions of cancer and anal intraepithelial neoplasia (AIN) using the random effects model.
Results: From 2974 initial search results, 12 studies were included in the review, with 48,365 resected specimens from hemorrhoidectomy. Among these, there were 11 retrospective studies and one prospective study. A meta-analysis of 11 studies revealed that the prevalence of anal cancer was low, at 0.13% (95% CI: 0.05%-0.31%). The prevalence of anal cancer and AIN combined was 1.16% (95% CI: 0.53%-2.52%).
Conclusion: This literature review estimated the probability of malignancy detection in hemorrhoid specimens sent for histopathological evaluation. The low incidence of malignant findings implies that routine analysis of hemorrhoidectomy samples may not be cost-effective. However, existing studies have yet to establish definitive risk factors for abnormal histological diagnoses to aid in the selection of specimens for selective histopathology.
(© 2024 The Author(s). World Journal of Surgery published by John Wiley & Sons Ltd on behalf of International Society of Surgery/Société Internationale de Chirurgie (ISS/SIC).)
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فهرسة مساهمة: Keywords: anal cancer; hemorrhoidectomy; hemorrhoids; histology; systematic review
تواريخ الأحداث: Date Created: 20240527 Date Completed: 20240801 Latest Revision: 20240801
رمز التحديث: 20240802
DOI: 10.1002/wjs.12235
PMID: 38797982
قاعدة البيانات: MEDLINE
الوصف
تدمد:1432-2323
DOI:10.1002/wjs.12235