دورية أكاديمية
أعرض في EDS

dbEBV: A database of Epstein-Barr virus variants and their correlations with human health.

التفاصيل البيبلوغرافية
العنوان: dbEBV: A database of Epstein-Barr virus variants and their correlations with human health.
المؤلفون: Xie R; State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou 510060, PR China., Cao B; School of Life Sciences, Zhengzhou University, Zhengzhou, China., Wu Z; Shenzhen Longgang District Central Blood Station, Shenzhen 518172, China., Ouyang Y; State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou 510060, PR China., Chen H; Human Genetics, Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore 138672, Singapore., Zhai W; Key Laboratory of Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China., Liu ZX; State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou 510060, PR China., Xu M; State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou 510060, PR China., Guo G; Clinical Laboratory, The Third People's Hospital of Longgang District, Shenzhen 518115, China.
المصدر: Computational and structural biotechnology journal [Comput Struct Biotechnol J] 2024 Apr 17; Vol. 23, pp. 2076-2082. Date of Electronic Publication: 2024 Apr 17 (Print Publication: 2024).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier B.V. on behalf of Research Network of Computational and Structural Biotechnology Country of Publication: Netherlands NLM ID: 101585369 Publication Model: eCollection Cited Medium: Print ISSN: 2001-0370 (Print) Linking ISSN: 20010370 NLM ISO Abbreviation: Comput Struct Biotechnol J Subsets: PubMed not MEDLINE
أسماء مطبوعة: Publication: Amsterdam : Elsevier B.V. on behalf of Research Network of Computational and Structural Biotechnology
Original Publication: Gothenburg, Sweden : Research Network of Computational and Structural Biotechnology
مستخلص: Since Epstein-Barr virus (EBV) was discovered in 1964, it has been reported to be associated with various malignancies as well as benign diseases, and the pathogenicity of EBV has been widely studied. Several databases have been established to provide comprehensive information on the virus and its relation to diseases and introduce convenient analysis tools. Although they have greatly facilitated the analysis of EBV at the genome, gene, protein, or epitope level, they did not provide enough insight into the genomic variants of EBV, which have been suggested as relevant to diseases by multiple studies. Here, we introduce dbEBV, a comprehensive database of EBV genomic variation landscape, which contains 942 EBV genomes with 109,893 variants from different tissues or cell lines in 24 countries. The database enables the visualization of information with varying global frequencies and their relationship with the human health of each variant. It also supports phylogenetic analysis at the genome or gene level in subgroups of different characteristics. Information of interest can easily be reached with functions such as searching, browsing, and filtering. In conclusion, dbEBV is a convenient resource for exploring EBV genomic variants, freely available at http://dbebv.omicsbio.info.
Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(© 2024 The Authors.)
References: J Virol. 2005 Dec;79(24):15323-30. (PMID: 16306603)
J Virol. 2015 May;89(10):5222-37. (PMID: 25787276)
J Virol. 1990 Sep;64(9):4084-92. (PMID: 2166806)
J Virol. 2014 Aug;88(16):8743-53. (PMID: 24850736)
Nat Microbiol. 2019 Mar;4(3):404-413. (PMID: 30664667)
Nat Genet. 2011 May;43(5):491-8. (PMID: 21478889)
J Virol. 2011 Nov;85(21):11291-9. (PMID: 21880770)
J Virol. 1998 May;72(5):4038-48. (PMID: 9557692)
Cancer Sci. 2019 Apr;110(4):1132-1139. (PMID: 30697862)
Nat Genet. 2019 Jul;51(7):1131-1136. (PMID: 31209392)
Lab Invest. 1994 Jul;71(1):73-81. (PMID: 8041121)
Nat Rev Cancer. 2016 Dec;16(12):789-802. (PMID: 27687982)
J Virol. 2005 Aug;79(16):10709-17. (PMID: 16051863)
J Virol. 2004 Jul;78(13):7004-15. (PMID: 15194777)
Nucleic Acids Res. 2018 Jan 4;46(D1):D41-D47. (PMID: 29140468)
Rev Med Virol. 1998 Apr;8(2):61-66. (PMID: 10398495)
Am J Pathol. 1987 Oct;129(1):86-91. (PMID: 2821817)
Nucleic Acids Res. 2012 Jan;40(Database issue):D593-8. (PMID: 22006842)
Bioinformatics. 2009 Jul 15;25(14):1754-60. (PMID: 19451168)
Nucleic Acids Res. 2002 Jul 15;30(14):3059-66. (PMID: 12136088)
Lancet. 2019 Jul 6;394(10192):64-80. (PMID: 31178151)
Lancet. 1964 Mar 28;1(7335):702-3. (PMID: 14107961)
PLoS Pathog. 2015 Dec 22;11(12):e1005344. (PMID: 26694854)
Nature. 2017 Oct 5;550(7674):124-127. (PMID: 28953888)
N Engl J Med. 1988 Mar 24;318(12):733-41. (PMID: 2831453)
PLoS Pathog. 2011 Aug;7(8):e1002193. (PMID: 21901094)
Cell Rep. 2013 Oct 31;5(2):458-70. (PMID: 24120866)
Virology. 2006 Jun 20;350(1):164-70. (PMID: 16490228)
J Clin Invest. 2012 Apr;122(4):1487-502. (PMID: 22406538)
Virus Res. 2009 Aug;143(2):209-21. (PMID: 19596032)
BMC Genomics. 2017 May 19;18(1):394. (PMID: 28525990)
J Gen Virol. 1987 Nov;68 ( Pt 11):2853-62. (PMID: 2824665)
Nature. 1984 Jul 19-25;310(5974):207-11. (PMID: 6087149)
Nature. 1970 Dec 12;228(5276):1056-8. (PMID: 4320657)
Proc Natl Acad Sci U S A. 1984 Dec;81(23):7632-6. (PMID: 6209719)
Bioinformatics. 2006 Nov 1;22(21):2688-90. (PMID: 16928733)
Lancet. 1989 Sep 30;2(8666):761-5. (PMID: 2571010)
Nat Med. 2002 Oct;8(10):1098-104. (PMID: 12219084)
فهرسة مساهمة: Keywords: Disease; EBV; Genetic variant; Global distribution; Phylogenetic analysis
تواريخ الأحداث: Date Created: 20240528 Latest Revision: 20240529
رمز التحديث: 20240529
مُعرف محوري في PubMed: PMC11128781
DOI: 10.1016/j.csbj.2024.04.043
PMID: 38803518
قاعدة البيانات: MEDLINE
الوصف
تدمد:2001-0370
DOI:10.1016/j.csbj.2024.04.043