دورية أكاديمية
أعرض في EDS

Iodide enhances degradation of histidine sidechain and imidazoles and forms new iodinated aromatic disinfection byproducts during chlorination.

التفاصيل البيبلوغرافية
العنوان: Iodide enhances degradation of histidine sidechain and imidazoles and forms new iodinated aromatic disinfection byproducts during chlorination.
المؤلفون: Choi SY; Department of Civil and Environmental Engineering and Institute of Construction and Environmental Engineering, Seoul National University, Seoul, the Republic of Korea., Ji H; Department of Civil and Environmental Engineering and Institute of Construction and Environmental Engineering, Seoul National University, Seoul, the Republic of Korea., Park J; Department of Civil and Environmental Engineering and Institute of Construction and Environmental Engineering, Seoul National University, Seoul, the Republic of Korea., Choe JK; Department of Civil and Environmental Engineering and Institute of Construction and Environmental Engineering, Seoul National University, Seoul, the Republic of Korea. Electronic address: jkchoe@snu.ac.kr.
المصدر: Journal of hazardous materials [J Hazard Mater] 2024 Aug 05; Vol. 474, pp. 134748. Date of Electronic Publication: 2024 May 27.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9422688 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3336 (Electronic) Linking ISSN: 03043894 NLM ISO Abbreviation: J Hazard Mater Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Amsterdam : Elsevier,
مواضيع طبية MeSH: Imidazoles*/chemistry , Histidine*/chemistry , Disinfection* , Halogenation* , Water Pollutants, Chemical*/chemistry , Disinfectants*/chemistry , Iodides*/chemistry , Water Purification*/methods, Hydrogen-Ion Concentration
مستخلص: Peptide-bound histidines and imidazoles are important constituents of dissolved organic matter in water, and understanding the formation of halogenated disinfection byproduct (DBP) formation from these compounds during disinfection is important for ensuring a safe drinking water supply. Previous studies suggested that histidine has low reactivity with chlorine only; this study indicates that iodide substantially enhances histidine reactivity with the disinfectant at a time scale from days to hours. Mono- and di-iodinated histidines were identified as dominant transformation products with cumulative molar yields of 3.3 % at 6 h and they were stable in water over 7 days. These products were formed via electrophilic substitution of iodine to imidazole ring when hypoiodous acid reacted with histidine sidechain. Bromide minimally influenced the formation yields of these iodinated products, and higher pH increased yields up to 12 % for pH in the range 5-9. The cumulative concentration of low-molecular-weight DBPs, such as trihalomethanes and haloacetic acids, was less than 0.3 % under the same conditions. Similar iodinated imidazole analogs were also identified from other imidazoles (i.e., imidazole-carboxylic and phenyl-imidazole-carboxylic acids). This study demonstrated that peptide-bound histidine and imidazoles can serve as important precursors to iodinated aromatic DBPs, facilitating the identification of less-known iodinated DBPs.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 Elsevier B.V. All rights reserved.)
فهرسة مساهمة: Keywords: Amino acids; Imidazole; Iodinated disinfection byproducts; Iodination; Oxidation
المشرفين على المادة: 0 (Imidazoles)
4QD397987E (Histidine)
0 (Water Pollutants, Chemical)
0 (Disinfectants)
0 (Iodides)
تواريخ الأحداث: Date Created: 20240530 Date Completed: 20240625 Latest Revision: 20240625
رمز التحديث: 20240625
DOI: 10.1016/j.jhazmat.2024.134748
PMID: 38815391
قاعدة البيانات: MEDLINE
الوصف
تدمد:1873-3336
DOI:10.1016/j.jhazmat.2024.134748