Comparative study of antioxidant activities of Allium sativum (a novel variety, HG17) and Allium ampeloprasum (SMG): Revealing the higher potential of HG17 and analyzing its phytochemicals.

التفاصيل البيبلوغرافية
العنوان:	Comparative study of antioxidant activities of Allium sativum (a novel variety, HG17) and Allium ampeloprasum (SMG): Revealing the higher potential of HG17 and analyzing its phytochemicals.
المؤلفون:	Monika M; Department of Zoology, Institute of Integrated and Honors Studies, Kurukshetra University, Kurukshetra, Haryana, India., Dua A; Cell Biology Lab, Institute of Integrated and Honors Studies, Kurukshetra University, Kurukshetra, Haryana, India., Sharma S; Chemistry lab, Institute of Integrated and Honors Studies, Kurukshetra University, Kurukshetra, Haryana, India., Gupta S; Cell Biology Lab, Institute of Integrated and Honors Studies, Kurukshetra University, Kurukshetra, Haryana, India., Mittal A; Cell Biology Lab, Institute of Integrated and Honors Studies, Kurukshetra University, Kurukshetra, Haryana, India.
المصدر:	Journal of food science [J Food Sci] 2024 Jul; Vol. 89 (7), pp. 4250-4275. Date of Electronic Publication: 2024 Jun 03.
نوع المنشور:	Journal Article; Comparative Study
اللغة:	English
بيانات الدورية:	Publisher: Wiley on behalf of the Institute of Food Technologists Country of Publication: United States NLM ID: 0014052 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1750-3841 (Electronic) Linking ISSN: 00221147 NLM ISO Abbreviation: J Food Sci Subsets: MEDLINE
أسماء مطبوعة:	Publication: Malden, Mass. : Wiley on behalf of the Institute of Food Technologists Original Publication: Champaign, Ill. Institute of Food Technologists
مواضيع طبية MeSH:	Antioxidants/pharmacology , Antioxidants/analysis , Garlic/chemistry , Plant Extracts/pharmacology , Plant Extracts/chemistry , Phytochemicals/pharmacology , Phytochemicals/analysis , Phenols/analysis , Phenols/pharmacology , Flavonoids/analysis , Flavonoids/pharmacology , Allium/chemistry, Chromatography, High Pressure Liquid/methods
مستخلص:	Garlic, belonging to the genus Allium, is renowned for its rich antioxidant potential. Snow Mountain garlic (SMG) (Allium ampeloprasum) has been traditionally used for medicinal purposes because of its higher antioxidant potential. Considering its potential in medical therapies, we compared the antioxidant activity of SMG with a novel variety of Allium sativum, Hisar garlic 17 (HG17). Comparative antioxidant activity data (2,2-diphenyl-1-picrylhydrazyl and 2,2-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) revealed the higher antioxidant activity of HG17 than SMG, which prompted us to conduct a comprehensive phytochemical investigation to elucidate the factors contributing to antioxidant potential of HG17. To get a detailed antioxidant and phytoconstituents profiling, we differentially extracted HG17 by processing it in different forms (fresh, dry, heated, and aged) with two solvents (50% methanol and n-butanol). Our data (antioxidant activities, total phenolics, and flavonoids) showed that dry garlic methanolic extract (DgM) had maximum potential than other HG17 forms/solvents, which concludes that different extraction techniques had direct impact on the phenolics/flavonoids and antioxidant potential of the extracts. Further, phytochemical analysis of HG17 extracts by high resolution liquid chromatograph mass spectrometer quadrupole time of flight validated the maximum potential of DgM. LCMS revealed the presence of garcimangosone C, osmanthuside A, and protoaphin aglucone polyphenols exclusively in DgM compared to other HG17 extracts, which possibly contributing in its high antioxidant potential. The overall differential extraction and LCMS data of HG17 strongly depict that it may be used as an alternative of SMG under diverse medical applications. HG17 higher antioxidant potential and rich array of unique phytochemicals make it valuable for food and pharmaceutical industries to integrate into functional foods/therapeutics. PRACTICAL APPLICATION: Garlic unique phytochemical composition and its remarkable ability to scavenge different radicals make it valuable therapeutic asset to mitigate diseases associated with oxidative stress. SMG is well known for its anti-arthritic and anti-inflammatory properties. HG17 showed higher antioxidant potential than SMG and can be used as an alternative of SMG for anti-arthritic properties. (© 2024 Institute of Food Technologists.)
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معلومات مُعتمدة:	Council of Scientific and Industrial Research, India
فهرسة مساهمة:	Keywords: Allium sativum; HR‐LCMS‐QTOF; antioxidant assay; total flavonoid content; total phenolic content
المشرفين على المادة:	0 (Antioxidants) 0 (Plant Extracts) 0 (Phytochemicals) 0 (Phenols) 0 (Flavonoids)
تواريخ الأحداث:	Date Created: 20240603 Date Completed: 20240703 Latest Revision: 20240703
رمز التحديث:	20240703
DOI:	10.1111/1750-3841.17133
PMID:	38829746
قاعدة البيانات:	MEDLINE

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تدمد:	1750-3841
DOI:	10.1111/1750-3841.17133