دورية أكاديمية
Adenoid Cystic carcinoma of minor salivary glands (AdCCmSG): a multidisciplinary update.
| العنوان: | Adenoid Cystic carcinoma of minor salivary glands (AdCCmSG): a multidisciplinary update. |
|---|---|
| المؤلفون: | Romanò R; Head and Neck Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., De Felice F; Department of Radiotherapy, Policlinico Umberto I, 'Sapienza' University of Rome, Rome, Italy., Ferri A; Maxillo-Facial Surgery Division, Head and Neck Department, University Hospital of Parma, Parma, Italy., Della Monaca M; Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Rome, Italy.; Oncological and Reconstructive Maxillo-Facial Surgery Unit, Policlinico Umberto I, Rome, Italy., Maroldi R; Division of Radiology, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy., Licitra L; Head and Neck Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.; University of Milan, Milan, Italy., Locati LD; Translational Oncology Unit, Istituto di Ricerca e Cura a carattere scientifico (IRCCS) Istituti Clinici Scientifici (ICS) Maugeri, Pavia, Italy.; Department of Internal Medicine and Medical Therapy, University of Pavia, Pavia, Italy., Alfieri S; Head and Neck Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. |
| المصدر: | Expert review of anticancer therapy [Expert Rev Anticancer Ther] 2024 Jul; Vol. 24 (7), pp. 567-580. Date of Electronic Publication: 2024 Jun 04. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Taylor & Francis Country of Publication: England NLM ID: 101123358 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-8328 (Electronic) Linking ISSN: 14737140 NLM ISO Abbreviation: Expert Rev Anticancer Ther Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2015- : Abingdon, Oxford : Taylor & Francis Original Publication: London : Future Drugs Ltd., c2001- |
| مواضيع طبية MeSH: | Carcinoma, Adenoid Cystic*/therapy , Carcinoma, Adenoid Cystic*/pathology , Carcinoma, Adenoid Cystic*/diagnosis , Salivary Gland Neoplasms*/therapy , Salivary Gland Neoplasms*/pathology , Salivary Gland Neoplasms*/diagnosis , Salivary Glands, Minor*/pathology, Humans ; Patient Care Team/organization & administration ; Practice Guidelines as Topic |
| مستخلص: | Introduction: Adenoid cystic carcinoma of minor salivary glands (AdCCmSG) represents a 'rarity in the rarity,' posing a clinical challenge in lack of standardized, evidence-based recommendations. At present, AdCCmSG management is mostly translated from major salivary gland cancers (MSGCs). Ideally, AdCCmSG diagnostic-therapeutic workup should be discussed and carried out within a multidisciplinary, high-expertise setting, including pathologists, surgeons, radiation oncologists and medical oncologists. Areas Covered: The present review provides an overview of epidemiology and pathologic classification. Moreover, the most recent, clinically relevant updates in the treatment of AdCCmSG (Pubmed searches, specific guidelines) are critically discussed, aiming to a better understanding of this rare pathologic entity, potentially optimizing the care process, and offering a starting point for reflection on future therapeutic developments. Expert Opinion: The management of rare cancers is often hindered by limited data and clinical trials, lack of evidence-based guidelines, and hardly represented disease heterogeneity, which cannot be successfully tackled with a 'one-size-fits-all' approach. Our goal is to address these potential pitfalls, providing an easy-to-use, updated, multidisciplinary collection of expert opinions concerning AdCCmSG management as of today's clinical practice. We will also cover the most promising future perspectives, based on the potential therapeutic targets highlighted within AdCCmSG's molecular background. |
| فهرسة مساهمة: | Keywords: Adenoid Cystic carcinoma (AdCC); head and neck; histotype; minor salivary gland cancer (mSGC); radiation therapy; surgery; targeted therapy |
| تواريخ الأحداث: | Date Created: 20240604 Date Completed: 20240620 Latest Revision: 20240620 |
| رمز التحديث: | 20240620 |
| DOI: | 10.1080/14737140.2024.2357806 |
| PMID: | 38832770 |
| قاعدة البيانات: | MEDLINE |
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