دورية أكاديمية
Cognitive Effects of Electroconvulsive Therapy in Schizophrenia: A Systematic Review.
| العنوان: | Cognitive Effects of Electroconvulsive Therapy in Schizophrenia: A Systematic Review. |
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| المؤلفون: | Vaccarino SR; Cumming School of Medicine, University of Calgary, Alberta, Canada., Vaccarino AL; Indoc Research, Toronto, Canada.; Corresponding Author: Anthony L. Vaccarino, PhD, Indoc Research, 1 Richmond St W, Ste 401, Toronto, ON M5H 3W4, Canada (avaccarino@indocresearch.org). |
| المصدر: | The Journal of clinical psychiatry [J Clin Psychiatry] 2024 Jun 05; Vol. 85 (2). Date of Electronic Publication: 2024 Jun 05. |
| نوع المنشور: | Journal Article; Systematic Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Physicians Postgraduate Press Country of Publication: United States NLM ID: 7801243 Publication Model: Electronic Cited Medium: Internet ISSN: 1555-2101 (Electronic) Linking ISSN: 01606689 NLM ISO Abbreviation: J Clin Psychiatry Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Memphis, Tenn., Physicians Postgraduate Press. |
| مواضيع طبية MeSH: | Electroconvulsive Therapy*/adverse effects, Humans ; Schizophrenia, Treatment-Resistant/therapy ; Cognitive Dysfunction/etiology ; Cognitive Dysfunction/therapy ; Cognition ; Schizophrenia/therapy ; Schizophrenic Psychology |
| مستخلص: | Objective: To determine the objective cognitive effects of electroconvulsive therapy (ECT) in treatment-resistant schizophrenia (TRS). Data Sources: A database search of MEDLINE, PsycINFO, and Embase was conducted on September 22, 2022, using the search terms "schizophrenia" and "electroconvulsive therapy." The search was limited to the articles published from 1985 to present, in English, and human studies. Study Selection: A total of 4293 articles were identified. After screening by title and full text, 17 articles met eligibility criteria. Controlled, open-label, and retrospective studies of acute, maintenance, or continuation ECT were included. An objective cognitive measure(s) had to be the primary or secondary outcome of the study, with no other interventions administered, besides standard-of-care treatment (ie, antipsychotics). Data Extraction: Data regarding the study design, type of ECT provided, cognitive outcome measures, and change in cognitive performance pre- to post-ECT were extracted. Results are presented as a narrative review. Results: Overall, ECT was not associated with any significant cognitive deficits in participants with TRS across the domains of global cognition, attention, language, visuospatial function, and executive function. Findings for immediate effects on memory were equivocal, but the majority of studies found no change or an improvement in memory after treatment. Conclusions: The current evidence supports the conclusion that ECT does not have negative long-term effects on cognition among patients with TRS. Larger, sham-controlled trials are needed to support these conclusions. All studies in this review assessed ECT adjunct to antipsychotics; therefore, the cognitive effects of ECT independent of antipsychotics remain unclear. (© Copyright 2024 Physicians Postgraduate Press, Inc.) |
| تواريخ الأحداث: | Date Created: 20240605 Date Completed: 20240605 Latest Revision: 20240607 |
| رمز التحديث: | 20240607 |
| DOI: | 10.4088/PCC.23r15045 |
| PMID: | 38836867 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1555-2101 |
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| DOI: | 10.4088/PCC.23r15045 |