دورية أكاديمية
Assessment of the effects of 2,4-D-dichlorophenoxyacetic acid-based herbicide exposure in eggs and embryos of golden apple snails using OCT.
| العنوان: | Assessment of the effects of 2,4-D-dichlorophenoxyacetic acid-based herbicide exposure in eggs and embryos of golden apple snails using OCT. |
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| المؤلفون: | Thanomsit C, Khumsopha C, Saetiew J, Meemon P, Nanthanawat P, Saowakoon S |
| المصدر: | Applied optics [Appl Opt] 2024 May 01; Vol. 63 (13), pp. 3712-3724. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Optica Publishing Group Country of Publication: United States NLM ID: 0247660 Publication Model: Print Cited Medium: Internet ISSN: 1539-4522 (Electronic) Linking ISSN: 1559128X NLM ISO Abbreviation: Appl Opt Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Washington, DC : Optica Publishing Group Original Publication: Easton, Pa., Optical Society of America. |
| مواضيع طبية MeSH: | 2,4-Dichlorophenoxyacetic Acid*/pharmacology , 2,4-Dichlorophenoxyacetic Acid*/toxicity , Tomography, Optical Coherence*/methods , Herbicides*/pharmacology , Herbicides*/toxicity , Embryo, Nonmammalian*/drug effects , Embryo, Nonmammalian*/embryology, Animals ; Snails/embryology ; Snails/drug effects ; Ovum/drug effects |
| مستخلص: | This study aimed to evaluate the effects of herbicide 2, 4-D-dichlorophenoxy acetic acid on golden apple snail eggs and embryos. Additionally, the study assessed the applicability of optical coherence tomography (OCT), a non-invasive depth cross-sectional microscopic imaging technique, as a novel method, to the best of our knowledge, for studying morphological changes in golden apple snail eggs and embryos, in comparison to the conventional approach of using white light microscopy. The study revealed that the herbicide 2,4-D-dichlorophenoxy acetic acid affected the hatchery rate and morphological changes of the eggs and embryos. The lethal concentration (LC50), representing the concentration of a substance that is expected to cause death in half of the population being studied, of the golden apple eggs and embryos increased with longer exposure time and higher concentrations. The estimated median effective concentration (EC50), which denotes the concentration producing the desired effect in 50% of the exposed golden apple embryos, exhibited a similar trend of change as the LC50. When compared to the microscopic study, it was observed that OCT could be employed to investigate morphological changes of golden apple snail eggs and embryos, enabling evaluation of alterations in both 2D and 3D structures. |
| المشرفين على المادة: | 2577AQ9262 (2,4-Dichlorophenoxyacetic Acid) 0 (Herbicides) |
| تواريخ الأحداث: | Date Created: 20240610 Date Completed: 20240610 Latest Revision: 20240610 |
| رمز التحديث: | 20240610 |
| DOI: | 10.1364/AO.503470 |
| PMID: | 38856558 |
| قاعدة البيانات: | MEDLINE |
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