دورية أكاديمية
أعرض في EDS

A cross-sectional National Health and Nutrition Examination survey-based study of the association between systemic immune-inflammation index and blood urea nitrogen levels in United States adolescents.

التفاصيل البيبلوغرافية
العنوان: A cross-sectional National Health and Nutrition Examination survey-based study of the association between systemic immune-inflammation index and blood urea nitrogen levels in United States adolescents.
المؤلفون: Guo C; Comprehensive Pediatrics & Pulmonary and Critical Care Medicine, Kunming Children's Hospital, No.28, Shulin Street, Kunming, 650103, Yunnan Province, China., Cai Q; Pediatric Department, Qionghai People's Hospital, No.33, Fuhai Road, Qionghai, 571400, Hainan Province, China., Li Y; Comprehensive Pediatrics & Pulmonary and Critical Care Medicine, Kunming Children's Hospital, No.28, Shulin Street, Kunming, 650103, Yunnan Province, China., Li F; Comprehensive Pediatrics & Pulmonary and Critical Care Medicine, Kunming Children's Hospital, No.28, Shulin Street, Kunming, 650103, Yunnan Province, China., Liu K; Comprehensive Pediatrics & Pulmonary and Critical Care Medicine, Kunming Children's Hospital, No.28, Shulin Street, Kunming, 650103, Yunnan Province, China. ynkmlk@foxmail.com.
المصدر: Scientific reports [Sci Rep] 2024 Jun 10; Vol. 14 (1), pp. 13248. Date of Electronic Publication: 2024 Jun 10.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : Nature Publishing Group, copyright 2011-
مواضيع طبية MeSH: Blood Urea Nitrogen* , Nutrition Surveys* , Inflammation*/blood, Humans ; Adolescent ; Female ; Male ; Cross-Sectional Studies ; United States/epidemiology
مستخلص: Blood urea nitrogen (BUN) level is one of the commonly used indicators to assess renal function and systemic immune-inflammatory status. In the adolescent population, changes in BUN levels may be associated with a variety of factors, including physiologic dehydration, lifestyle influences such as nutritional intake, physical activity, and possible endocrine or metabolic disorders. In recent years, more and more studies have shown that BUN levels are not only a reflection of kidney function, but it may also be related to the inflammatory state of the body. The Systemic Immune Inflammatory Index (SII) is a comprehensive index that takes into account platelet counts, neutrophil and lymphocyte counts, and is thought to be effective in reflecting the body's immune status and inflammatory response. However, research on the relationship between the two, SII and BUN, remains understudied in the adolescent population. The purpose of this study was to examine the relationship between SII and BUN levels in a population of American adolescents and to further analyze the factors that influence it. We conducted a cross-sectional study using data from the National Health and Nutrition Examination Survey (NHANES) database. Using descriptive statistics, correlation analysis, and regression analysis, we explored the relationship between SII and BUN levels. We found a significant negative correlation between SII and BUN levels, with BUN levels decreasing when SII levels increased (BUN as the dependent variable and SII as the outcome variable). We performed a multiple regression analysis of this relationship, controlling for possible confounders such as gender, age, race, and BMI, and found that this negative correlation remained significant. Our findings reveal an important relationship between SII and BUN levels and provide new perspectives for understanding adolescent health.
(© 2024. The Author(s).)
References: Pediatrics. 2019 Dec;144(6):. (PMID: 31740496)
Eur J Med Res. 2023 Dec 9;28(1):575. (PMID: 38066657)
Clin Chem. 1997 Jun;43(6 Pt 1):913-4. (PMID: 9191538)
BMC Public Health. 2023 Jul 24;23(1):1416. (PMID: 37488531)
Ann Med. 2021 Dec;53(1):1827-1838. (PMID: 34647517)
Eur Rev Med Pharmacol Sci. 2021 Feb;25(3):1302-1310. (PMID: 33629300)
BMC Pulm Med. 2023 Aug 10;23(1):295. (PMID: 37563621)
Clin Obes. 2020 Feb;10(1):e12345. (PMID: 31692279)
Front Pediatr. 2022 Dec 02;10:1059083. (PMID: 36533239)
Ocul Immunol Inflamm. 2022 Apr 3;30(3):588-592. (PMID: 32990489)
Nat Rev Immunol. 2013 Nov;13(11):831-8. (PMID: 24052146)
Sci Rep. 2019 Mar 1;9(1):3284. (PMID: 30824727)
J Cell Physiol. 2019 May;234(5):5555-5563. (PMID: 30353545)
Immunol Rev. 2017 Jul;278(1):101-115. (PMID: 28658545)
Int J Environ Res Public Health. 2020 Oct 30;17(21):. (PMID: 33143164)
J Pediatr. 2012 Apr;160(4):615-620.e2. (PMID: 22099686)
Endocrinology. 2012 Jun;153(6):2544-50. (PMID: 22434079)
Sci Rep. 2024 Jan 23;14(1):2013. (PMID: 38263234)
J Gastrointest Surg. 2021 May;25(5):1124-1133. (PMID: 32607856)
Ann N Y Acad Sci. 2017 Apr;1393(1):21-33. (PMID: 28436102)
Br J Psychiatry. 1998 Dec;173:508-13. (PMID: 9926080)
PLoS One. 2018 Mar 20;13(3):e0194044. (PMID: 29558500)
Med Sci Sports Exerc. 2002 Dec;34(12):1941-50. (PMID: 12471300)
Arch Dis Child. 2012 Oct;97(10):885-8. (PMID: 22833407)
Proc Biol Sci. 2015 Dec 22;282(1821):20143085. (PMID: 26702035)
Front Med (Lausanne). 2022 Jul 14;9:909789. (PMID: 35911383)
Adv Rheumatol. 2018 Sep 18;58(1):30. (PMID: 30657082)
Clin Cancer Res. 2014 Dec 1;20(23):6212-22. (PMID: 25271081)
Med Sport Sci. 2010;55:14-31. (PMID: 20956857)
J Appl Physiol. 1974 Aug;37(2):247-8. (PMID: 4850854)
Cancer Manag Res. 2017 Dec 14;9:849-867. (PMID: 29276407)
BMC Geriatr. 2024 Jan 15;24(1):61. (PMID: 38225566)
J Transl Med. 2023 Oct 4;21(1):691. (PMID: 37794370)
Pediatr Res. 2012 Aug;72(2):179-85. (PMID: 22580717)
Pharmacol Rev. 1998 Mar;50(1):107-41. (PMID: 9549760)
J Adolesc Health. 2013 Nov;53(5):562-72. (PMID: 23998849)
Front Neuroendocrinol. 2014 Aug;35(3):347-69. (PMID: 24793874)
Autoimmun Rev. 2021 Apr;20(4):102775. (PMID: 33609790)
Neuropsychiatr Dis Treat. 2013;9:449-61. (PMID: 23579318)
Front Neurol. 2021 Oct 11;12:745175. (PMID: 34707561)
J Affect Disord. 2018 Apr 1;230:108-117. (PMID: 29407534)
Endocr Dev. 2010;17:77-85. (PMID: 19955758)
Vital Health Stat 2. 2012 May;(155):1-39. (PMID: 22788053)
Eur J Neurosci. 2022 May;55(9-10):2311-2325. (PMID: 33458889)
فهرسة مساهمة: Keywords: Adolescents; Blood urea nitrogen; Cross-sectional study; Systemic Immune Inflammatory Index
تواريخ الأحداث: Date Created: 20240610 Date Completed: 20240610 Latest Revision: 20240613
رمز التحديث: 20240613
مُعرف محوري في PubMed: PMC11164917
DOI: 10.1038/s41598-024-64073-w
PMID: 38858433
قاعدة البيانات: MEDLINE
الوصف
تدمد:2045-2322
DOI:10.1038/s41598-024-64073-w