دورية أكاديمية

Association of traditional and novel obesity indicators with stroke risk: Findings from the Rural Chinese cohort study.

التفاصيل البيبلوغرافية
العنوان: Association of traditional and novel obesity indicators with stroke risk: Findings from the Rural Chinese cohort study.
المؤلفون: Zhang D; Department of General Practice, The Affiliated Luohu Hospital of Shenzhen University Medical School, Shenzhen, Guangdong, People's Republic of China; Department of Allergy and Clinical Immunology, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China., Huo W; Department of Biostatistics and Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou, Henan, People's Republic of China., Chen W; Department of Biostatistics and Epidemiology, School of Public Health, Shenzhen University Medical School, Shenzhen, Guangdong, People's Republic of China., Li X; Department of Biostatistics and Epidemiology, School of Public Health, Shenzhen University Medical School, Shenzhen, Guangdong, People's Republic of China., Qin P; Department of Medical Record Management, Shenzhen Qianhai Shekou Free Trade Zone Hospital, Shenzhen, Guangdong, People's Republic of China., Zhang M; Department of Biostatistics and Epidemiology, School of Public Health, Shenzhen University Medical School, Shenzhen, Guangdong, People's Republic of China; Guangdong Provincial Key Laboratory of Regional Immunity and Diseases, Shenzhen University Medical School, Shenzhen, Guangdong, People's Republic of China., Li J; Department of Allergy and Clinical Immunology, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China., Sun X; Department of General Practice, The Affiliated Luohu Hospital of Shenzhen University Medical School, Shenzhen, Guangdong, People's Republic of China., Liu Y; Department of General Practice, The Affiliated Luohu Hospital of Shenzhen University Medical School, Shenzhen, Guangdong, People's Republic of China., Hu D; Department of General Practice, The Affiliated Luohu Hospital of Shenzhen University Medical School, Shenzhen, Guangdong, People's Republic of China. Electronic address: hud@szu.edu.cn.
المصدر: Nutrition, metabolism, and cardiovascular diseases : NMCD [Nutr Metab Cardiovasc Dis] 2024 Sep; Vol. 34 (9), pp. 2065-2074. Date of Electronic Publication: 2024 May 06.
نوع المنشور: Journal Article; Comparative Study
اللغة: English
بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9111474 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1590-3729 (Electronic) Linking ISSN: 09394753 NLM ISO Abbreviation: Nutr Metab Cardiovasc Dis Subsets: MEDLINE
أسماء مطبوعة: Publication: 2005- : Amsterdam : Elsevier
Original Publication: [Heidelberg] : Springer International, c1991-
مواضيع طبية MeSH: Body Mass Index* , Waist Circumference* , Obesity*/epidemiology , Obesity*/diagnosis , Obesity*/physiopathology , Rural Health* , Adiposity* , Ischemic Stroke*/epidemiology , Ischemic Stroke*/diagnosis, Humans ; Male ; Female ; Middle Aged ; China/epidemiology ; Risk Factors ; Risk Assessment ; Incidence ; Aged ; Time Factors ; Prognosis ; Predictive Value of Tests ; Adult ; Lipid Accumulation Product ; Hemorrhagic Stroke/epidemiology ; Hemorrhagic Stroke/diagnosis ; Prospective Studies ; Stroke/epidemiology ; Stroke/diagnosis ; East Asian People
مستخلص: Background and Aims: Few researchers have compared the effectiveness of traditional and novel obesity indicators in predicting stroke incidence. We aimed to evaluate the associations between six obesity indices and stroke risk, and to further identify the optimal indicator.
Methods and Results: A total of 14,539 individuals from the Rural Chinese Cohort Study were included in the analyses. We used the Cox proportional hazards regression models to evaluate the association between six obesity indices (including body mass index [BMI], waist circumference [WC], conicity index [C-index], lipid accumulation product [LAP], visceral adiposity index [VAI], and Chinese visceral adiposity index [CVAI]) and stroke risk. Receiver operating characteristic curves were employed to compare their predictive ability on stroke risk. During a median follow-up period of 11.13 years, a total of 1257 cases of stroke occurred. In the multiple-adjusted Cox regression model, WC, BMI, C-index, and CVAI were positively associated with ischemic stroke (P < 0.01) rather than hemorrhagic stroke risk. Dose-response analyses showed a linear correlation of WC, BMI, C-index, and LAP (P overall <0.05, and P nonlinear >0.05), but a non-linear correlation of CVAI (P overall <0.05, and P nonlinear <0.05) with the risk of ischemic stroke. CVAI demonstrates the highest areas under the curves (AUC: 0.661, 95% CI: 0.653-0.668), indicating a superior predictive ability for ischemic stroke occurrence compared to other five indices (P < 0.001).
Conclusion: WC, BMI, C-index, LAP, and CVAI were all positively related to the risk of ischemic stroke, among which CVAI exhibited stronger predictive ability for ischemic stroke.
Competing Interests: Declaration of competing interest The author declare that they have no competing interests.
(Copyright © 2024 The Italian Diabetes Society, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.)
فهرسة مساهمة: Keywords: Chinese visceral adiposity index; Cohort; Obesity indices; Receiver operating characteristic; Stroke
تواريخ الأحداث: Date Created: 20240612 Date Completed: 20240804 Latest Revision: 20240804
رمز التحديث: 20240805
DOI: 10.1016/j.numecd.2024.05.001
PMID: 38866612
قاعدة البيانات: MEDLINE
الوصف
تدمد:1590-3729
DOI:10.1016/j.numecd.2024.05.001