دورية أكاديمية

Giant complete hydatidiform mole: a case report and review of the literature.

التفاصيل البيبلوغرافية
العنوان: Giant complete hydatidiform mole: a case report and review of the literature.
المؤلفون: Bonomo I; Department of Breast and Reconstructive Surgery, Institut Bergonié, Centre de Lutte Contre le Cancer de Bordeaux, 229 Cours de l'Argonne, 33076, Bordeaux, France. bonomo.iris@gmail.com., Fopa S; Department of Obstetrics, Cliniques Universitaires Saint-Luc, 1200, Brussels, Belgique., Van Vinckenroy G; Deparment of Gynecology and Obstetrics, Grand Hôpital de Charleroi, 6000, Charleroi, Belgique., Maillard C; Department of Gynecology and Andrology, Cliniques Universitaires Saint-Luc, 1200, Brussels, Belgique.
المصدر: Journal of medical case reports [J Med Case Rep] 2024 Jun 13; Vol. 18 (1), pp. 277. Date of Electronic Publication: 2024 Jun 13.
نوع المنشور: Case Reports; Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101293382 Publication Model: Electronic Cited Medium: Internet ISSN: 1752-1947 (Electronic) Linking ISSN: 17521947 NLM ISO Abbreviation: J Med Case Rep Subsets: MEDLINE
أسماء مطبوعة: Original Publication: [London] : BioMed Central, [2007-
مواضيع طبية MeSH: Hydatidiform Mole*/pathology , Hydatidiform Mole*/diagnosis , Hydatidiform Mole*/surgery , Hydatidiform Mole*/diagnostic imaging , Uterine Neoplasms*/surgery , Uterine Neoplasms*/pathology , Uterine Neoplasms*/diagnosis, Humans ; Female ; Pregnancy ; Young Adult ; Dilatation and Curettage ; Chorionic Gonadotropin/blood
مستخلص: Background: This case describes the youngest patient documented in the literature who presented with a giant hydatidiform mole, effectively addressed through conservative treatment.
Case Presentation: Our department received a 20-year-old Caucasian patient who was admitted due to significant metrorrhagia in an undisclosed pregnancy. During examination, we identified a massive, highly vascularized hydatidiform mole measuring 22 cm (cm). We performed a surgical dilatation and curettage. The anatomopathological findings confirmed the presence of a complete hydatidiform mole (CHM). Following the established guidelines, we conducted weekly monitoring of human chorionic gonadotropin (hCG). Unfortunately, the patient discontinued the follow-up and became pregnant again before achieving hCG negativation.
Conclusion: This case suggests that conservative treatment is a viable option regardless of the size of gestational trophoblastic disease (GTD), especially when the preservation of fertility is a crucial consideration, as effectively demonstrated in our case.
(© 2024. The Author(s).)
References: Crit Rev Oncol Hematol. 2017 Jun;114:77-90. (PMID: 28477749)
Curr Opin Obstet Gynecol. 2021 Feb 1;33(1):7-12. (PMID: 33337613)
F1000Res. 2019 Apr 10;8:. (PMID: 31001418)
Arch Gynecol Obstet. 2017 Jan;295(1):173-187. (PMID: 27549089)
Gynecol Oncol. 2021 Dec;163(3):605-613. (PMID: 34686354)
Lancet. 2010 Aug 28;376(9742):717-29. (PMID: 20673583)
Open Med (Wars). 2021 Jul 10;16(1):1038-1042. (PMID: 34286100)
Semin Ultrasound CT MR. 2019 Aug;40(4):332-349. (PMID: 31375173)
Obstet Gynecol Sci. 2016 Nov;59(6):548-553. (PMID: 27896261)
Best Pract Res Clin Obstet Gynaecol. 2021 Jul;74:3-28. (PMID: 34219021)
Int J Gynaecol Obstet. 2021 Oct;155 Suppl 1:86-93. (PMID: 34669197)
Int J Gynaecol Obstet. 2006 May;93(2):156-7. (PMID: 16542659)
Arch Gynecol Obstet. 2009 Mar;279(3):411-3. (PMID: 18642009)
Radiographics. 2017 Mar-Apr;37(2):681-700. (PMID: 28287945)
Ann Chir Gynaecol Suppl. 1994;208:62-3. (PMID: 8092776)
Int J Gynecol Cancer. 2005 Jan-Feb;15(1):163-6. (PMID: 15670312)
Ultrasound Obstet Gynecol. 2006 Jan;27(1):56-60. (PMID: 16273594)
Eur J Cancer. 2020 May;130:228-240. (PMID: 32247260)
Curr Treat Options Oncol. 2017 Aug 24;18(10):58. (PMID: 28840513)
Gynecol Oncol. 2019 Oct;155(1):8-12. (PMID: 31375268)
BMJ Case Rep. 2012 Sep 11;2012:. (PMID: 22967678)
Obstet Gynecol. 2020 Jan;135(1):12-23. (PMID: 31809433)
Int J Gynaecol Obstet. 2002 Jun;77(3):285-7. (PMID: 12065144)
فهرسة مساهمة: Keywords: Case report; Gestational trophoblastic disease; Human chorionic gonadotropin; Hydatidiform mole; Molar pregnancy
المشرفين على المادة: 0 (Chorionic Gonadotropin)
تواريخ الأحداث: Date Created: 20240612 Date Completed: 20240613 Latest Revision: 20240615
رمز التحديث: 20240615
مُعرف محوري في PubMed: PMC11170884
DOI: 10.1186/s13256-024-04474-7
PMID: 38867300
قاعدة البيانات: MEDLINE
الوصف
تدمد:1752-1947
DOI:10.1186/s13256-024-04474-7