دورية أكاديمية

Clinical course of asymptomatic duodenal subepithelial lesions.

التفاصيل البيبلوغرافية
العنوان: Clinical course of asymptomatic duodenal subepithelial lesions.
المؤلفون: Kang S; Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.; Department of Internal Medicine, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea., Park K; Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.; Department of Internal Medicine, Nowon Eulji Medical Center, Eulji University School of Medicine, Seoul, Korea., Kim DH; Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea., Kim Y; Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea., Na HK; Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea., Lee JH; Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea., Ahn JY; Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea., Jung KW; Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea., Choi KD; Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea., Song HJ; Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea., Lee GH; Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea., Jung HY; Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
المصدر: The Korean journal of internal medicine [Korean J Intern Med] 2024 Jul; Vol. 39 (4), pp. 603-611. Date of Electronic Publication: 2024 Jun 13.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Korean Association of Internal Medicine Country of Publication: Korea (South) NLM ID: 8712418 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2005-6648 (Electronic) Linking ISSN: 12263303 NLM ISO Abbreviation: Korean J Intern Med Subsets: MEDLINE
أسماء مطبوعة: Original Publication: [Seoul] : Korean Association of Internal Medicine
مواضيع طبية MeSH: Duodenal Neoplasms*/pathology , Duodenal Neoplasms*/surgery , Endoscopy, Digestive System* , Asymptomatic Diseases*, Humans ; Retrospective Studies ; Female ; Male ; Middle Aged ; Aged ; Adult ; Lipoma/pathology ; Lipoma/surgery ; Lipoma/diagnostic imaging ; Disease Progression ; Gastrointestinal Stromal Tumors/pathology ; Gastrointestinal Stromal Tumors/surgery ; Gastrointestinal Stromal Tumors/diagnostic imaging ; Time Factors ; Endoscopic Ultrasound-Guided Fine Needle Aspiration ; Duodenal Diseases/pathology ; Duodenal Diseases/surgery
مستخلص: Background/aims: There is limited knowledge regarding the management of duodenal subepithelial lesions (SELs) owing to a lack of understanding of their natural course. This study aimed to assess the natural course of asymptomatic duodenal SELs and provide management recommendations.
Methods: Patients diagnosed with duodenal SELs and followed up for a minimum of 6 months were retrospectively investigated.
Results: Among the 443,533 patients who underwent esophagogastroduodenoscopy between 2008 and 2020, duodenal SELs were identified in 0.39% (1,713 patients). Among them, 396 duodenal SELs were monitored for a median period of 72.5 months (interquartile range, 37.7-111.3 mo). Of them, 16 SELs (4.0%) showed substantial changes in size or morphology at a median follow-up of 35.1 months (interquartile range, 21.7-51.4 mo). Of these SELs with substantial changes, tissues of two SELs were acquired using endoscopic ultrasound-guided fine needle aspiration biopsy: one was a lipoma and the other was non-diagnostic. Three SELs were surgically or endoscopically removed; two were diagnosed as gastrointestinal stromal tumors, and one was a lipoma. An initial size of 20 mm or larger was associated with substantial changes during follow-up (p = 0.016).
Conclusion: While the majority of duodenal SELs may not exhibit substantial interval changes, regular follow-up with endoscopy may be necessary for cases with an initial size of 20 mm or larger, considering a possibility of malignancy.
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فهرسة مساهمة: Keywords: Duodenum; Endosonography; Gastrointestinal stromal tumors; Subepithelial lesions
تواريخ الأحداث: Date Created: 20240613 Date Completed: 20240710 Latest Revision: 20240714
رمز التحديث: 20240714
مُعرف محوري في PubMed: PMC11236810
DOI: 10.3904/kjim.2023.358
PMID: 38867644
قاعدة البيانات: MEDLINE
الوصف
تدمد:2005-6648
DOI:10.3904/kjim.2023.358