دورية أكاديمية
The association between children's exposure to pesticides and asthma, wheezing, and lower respiratory tract infections. A systematic review and meta-analysis.
| العنوان: | The association between children's exposure to pesticides and asthma, wheezing, and lower respiratory tract infections. A systematic review and meta-analysis. |
|---|---|
| المؤلفون: | Keleb A; Department of Environmental Health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia., Daba C; Department of Environmental Health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia., Asmare L; Department of Epidemiology and Biostatistics School of Public Health, College of Medicine and Health Science Wollo University, Dessie, Ethiopia., Bayou FD; Department of Epidemiology and Biostatistics School of Public Health, College of Medicine and Health Science Wollo University, Dessie, Ethiopia., Arefaynie M; Department of Reproductive and Family Health, School of Public Health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia., Mohammed A; Department of Epidemiology and Biostatistics School of Public Health, College of Medicine and Health Science Wollo University, Dessie, Ethiopia., Tareke AA; Amref Health in Africa, COVID-19 Vaccine/EPI Technical Assistant at West Gondar Zonal Health Department, Gondar, Ethiopia., Kebede N; Department of Health Promotion, School of Public Health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia., Tsega Y; Department of Health System and Management, School of Public Health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia., Endawkie A; Department of Epidemiology and Biostatistics School of Public Health, College of Medicine and Health Science Wollo University, Dessie, Ethiopia., Kebede SD; Department of Health Informatics, School of Public Health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia., Abera KM; Department of Health System and Management, School of Public Health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia., Abeje ET; Department of Epidemiology and Biostatistics School of Public Health, College of Medicine and Health Science Wollo University, Dessie, Ethiopia., Enyew EB; Department of Health Informatics, School of Public Health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia. |
| المصدر: | Frontiers in public health [Front Public Health] 2024 May 24; Vol. 12, pp. 1402908. Date of Electronic Publication: 2024 May 24 (Print Publication: 2024). |
| نوع المنشور: | Systematic Review; Meta-Analysis; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Frontiers Editorial Office Country of Publication: Switzerland NLM ID: 101616579 Publication Model: eCollection Cited Medium: Internet ISSN: 2296-2565 (Electronic) Linking ISSN: 22962565 NLM ISO Abbreviation: Front Public Health Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Lausanne : Frontiers Editorial Office |
| مواضيع طبية MeSH: | Asthma*/epidemiology , Asthma*/chemically induced , Respiratory Sounds*/etiology , Pesticides*/adverse effects , Respiratory Tract Infections*/epidemiology , Environmental Exposure*/adverse effects, Humans ; Child ; Child, Preschool ; Adolescent ; Infant |
| مستخلص: | Background: Exposure to pesticides is a global public health problem, especially for children. Its association with chronic respiratory disease among children has attracted considerable attention, but the existing evidence remains inconclusive and cannot be certain. Therefore, this systematic review and meta-analysis aim to determine the global pooled effect size of association with pesticide exposure and asthma, wheezing, and respiratory tract infections among children. Methods: A comprehensive search was conducted for relevant literature from electronic databases, including PubMed, Google Scholar, Hinari, Semantic Scholar, and Science Direct. Studies that provided effect size on the association between pesticide exposure and childhood asthma, wheezing, and respiratory tract infections in children were included. The articles were screened, data was extracted, and the quality of each study was assessed with four independent reviewers. Random effects models for significant heterogeneity and fixed effect models for homogeneous studies were conducted to estimate pooled effect sizes with 95% confidence intervals using Comprehensive Meta-Analysis version 3.3.070 and MetaXL version 2. Funnel plot and Higgins I 2 statistics were used to determine the heterogeneity of the included studies. Subgroup analyses were computed based on the types of pesticide exposure, study design, sample size category, and outcome assessment technique. Result: A total of 38 articles with 118,303 children less than 18 years of age were included in this meta-analysis. Pesticide exposure among children increased the risk of asthma by 24%; (OR = 1.24, 95% CI: 1.14-1.35) with extreme heterogeneity ( I 2 = 81%, p < 0.001). Exposure to pesticides increased the odds of developing wheezing among children by 34% (OR = 1.34, 95% CI: 1.14-1.57), with high heterogeneity ( I 2 = 79%, p < 0.001) and also increased the risk of developing lower respiratory tract infection by 79% (OR = 1.79, 95% CI: 1.45-2.21) with nonsignificant low heterogeneity ( I 2 = 30%, p -value = 0.18). Conclusion: This meta-analysis provided valuable evidence supporting the association between childhood asthma, wheezing, and lower respiratory tract infection with pesticide exposure. The findings would contribute to a better understanding of the estimate of the effect of pesticide exposure on respiratory health in children and inform evidence-based preventive strategies and public health interventions. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2024 Keleb, Daba, Asmare, Bayou, Arefaynie, Mohammed, Tareke, Kebede, Tsega, Endawkie, Kebede, Abera, Abeje and Enyew.) |
| References: | Toxics. 2023 Aug 30;11(9):. (PMID: 37755752) BMJ Open. 2015 Jun 09;5(6):e008446. (PMID: 26059525) J Epidemiol Glob Health. 2017 Sep;7(3):147-154. (PMID: 28756822) Allergol Immunopathol (Madr). 2020 Nov - Dec;48(6):523-529. (PMID: 32402625) Int J Environ Res Public Health. 2014 Aug 06;11(8):7820-40. (PMID: 25101767) J Asthma. 2020 Jun;57(6):601-609. (PMID: 30938205) J Allergy Clin Immunol. 2009 Oct;124(4):852-4. (PMID: 19767085) Environ Health Perspect. 2010 Dec;118(12):1768-74. (PMID: 21126939) Eur Respir Rev. 2014 Jun;23(132):180-92. (PMID: 24881073) Int J Environ Res Public Health. 2020 Sep 30;17(19):. (PMID: 33007939) Pediatrics. 2012 Dec;130(6):e1765-88. (PMID: 23184105) Environ Res. 2022 Dec;215(Pt 1):114230. (PMID: 36087771) Sci Total Environ. 1996 Sep;188 Suppl 1:S86-98. (PMID: 8966546) Environ Health. 2008 Dec 04;7:62. (PMID: 19055819) Environ Res. 2020 Jun;185:109366. (PMID: 32299029) Am J Epidemiol. 2014 Jun 1;179(11):1323-30. (PMID: 24780843) Sci Total Environ. 2018 Apr 15;621:75-84. (PMID: 29175623) Int J Environ Res Public Health. 2020 Apr 16;17(8):. (PMID: 32316194) Ecotoxicology. 2003 Feb-Aug;12(1-4):345-63. (PMID: 12739880) Int J Hyg Environ Health. 2021 Apr;233:113694. (PMID: 33556714) J Pediatr (Rio J). 2022 Nov-Dec;98(6):551-564. (PMID: 34982974) J Asthma. 2020 Nov;57(11):1227-1236. (PMID: 31311358) Toxicology. 2018 Dec 1;410:125-131. (PMID: 30266654) Neurotoxicology. 2008 Sep;29(5):833-8. (PMID: 18662718) Arch Environ Health. 2001 Nov-Dec;56(6):485-92. (PMID: 11958547) Toxics. 2021 Sep 21;9(9):. (PMID: 34564379) Toxicol Appl Pharmacol. 2013 Apr 15;268(2):157-77. (PMID: 23402800) Eur Respir J. 2010 May;35(5):987-93. (PMID: 19926750) Clin Toxicol (Phila). 2018 Dec;56(12):1213-1415. (PMID: 30576252) Environ Res. 2024 Feb 1;242:117604. (PMID: 38000632) Environ Int. 2018 Dec;121(Pt 1):435-442. (PMID: 30266014) Am J Respir Crit Care Med. 2002 Mar 1;165(5):683-9. (PMID: 11874814) Eur Respir Rev. 2015 Sep;24(137):462-73. (PMID: 26324808) Environ Res. 2018 Jul;164:93-99. (PMID: 29482188) Allergy. 2015 Jun;70(6):653-60. (PMID: 25753462) Risk Manag Healthc Policy. 2021 Mar 25;14:1287-1297. (PMID: 33790674) Environ Health Perspect. 2017 Aug 10;125(8):087007. (PMID: 28886594) Environ Int. 2014 Aug;69:133-40. (PMID: 24837163) Int J Epidemiol. 2021 Jan 23;49(6):1856-1869. (PMID: 32666076) J Occup Environ Med. 2012 Oct;54(10):1281-7. (PMID: 22995816) J Occup Health. 2009;51(6):488-97. (PMID: 19851039) J Agromedicine. 2018;23(4):327-335. (PMID: 30230435) Environ Res. 2016 Apr;146:125-35. (PMID: 26748225) Clin Exp Allergy. 2006 Oct;36(10):1236-41. (PMID: 17014430) J Agric Saf Health. 2000 May;6(2):103-15. (PMID: 10938756) Int J Hyg Environ Health. 2020 Apr;225:113474. (PMID: 32066110) Environ Health Perspect. 2005 Dec;113(12):1787-90. (PMID: 16330365) Int J Evid Based Healthc. 2015 Sep;13(3):147-53. (PMID: 26317388) Environ Health Perspect. 2015 Feb;123(2):179-85. (PMID: 25369257) J Expo Sci Environ Epidemiol. 2024 Mar;34(2):241-250. (PMID: 36765101) Eur Respir J. 2003 Sep;22(3):507-12. (PMID: 14516143) Eco Environ Health. 2023 Aug 22;2(4):208-218. (PMID: 38435359) Environ Res. 2007 Jan;103(1):79-86. (PMID: 17084836) Environ Res. 2019 Feb;169:189-195. (PMID: 30466012) Environ Health Perspect. 2004 May;112(6):760-5. (PMID: 15121522) Arch Environ Occup Health. 2015;70(4):218-24. (PMID: 25386741) Environ Int. 2022 May;163:107229. (PMID: 35405505) Eur Respir J. 2022 Nov 10;60(5):. (PMID: 35618276) J Agromedicine. 2020 Jan;25(1):106-114. (PMID: 31130077) Int J Public Health. 2023 Aug 22;68:1606174. (PMID: 37674664) Paediatr Perinat Epidemiol. 2003 Apr;17(2):212-20. (PMID: 12675789) BMC Public Health. 2020 Dec 7;20(1):1875. (PMID: 33287770) East Mediterr Health J. 2019 Nov 04;25(10):698-705. (PMID: 31774135) Environ Health Perspect. 2006 Feb;114(2):260-3. (PMID: 16451864) Arch Environ Occup Health. 2015;70(6):309-22. (PMID: 25147971) Sci Total Environ. 2017 Jan 1;575:525-535. (PMID: 27614863) Environ Res. 2017 Jul;156:559-570. (PMID: 28437652) Epidemiology. 2010 Sep;21(5):729-35. (PMID: 20616741) PLoS One. 2013 Jul 25;8(7):e69755. (PMID: 23936093) Thorax. 2023 Jan;78(1):41-49. (PMID: 35210357) |
| فهرسة مساهمة: | Keywords: asthma; children; chronic respiratory diseases; meta-analysis; pesticide exposure; respiratory tract infection; systematic review |
| المشرفين على المادة: | 0 (Pesticides) |
| تواريخ الأحداث: | Date Created: 20240613 Date Completed: 20240613 Latest Revision: 20240614 |
| رمز التحديث: | 20240614 |
| مُعرف محوري في PubMed: | PMC11167956 |
| DOI: | 10.3389/fpubh.2024.1402908 |
| PMID: | 38868160 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2296-2565 |
|---|---|
| DOI: | 10.3389/fpubh.2024.1402908 |