دورية أكاديمية
أعرض في EDS

Infant Formula with 50% or More of Palmitic Acid Bound to the sn-2 Position of Triacylglycerols Eliminate the Association between Formula-Feeding and the Increase of Fecal Palmitic Acid Levels in Newborns: An Exploratory Study.

التفاصيل البيبلوغرافية
العنوان: Infant Formula with 50% or More of Palmitic Acid Bound to the sn-2 Position of Triacylglycerols Eliminate the Association between Formula-Feeding and the Increase of Fecal Palmitic Acid Levels in Newborns: An Exploratory Study.
المؤلفون: Shoji H; Department of Pediatrics, Faculty of Medicine, Juntendo University, 3-1-3, Hongo, Bunkyo-ku, Tokyo 113-8431, Japan., Arai H; Department of Neonatology, Faculty of Medicine, Toho University, 6-11-1, Omorinishi, Ota-ku, Tokyo 143-8541, Japan., Kakiuchi S; Department of Pediatrics, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-8655, Japan., Ito A; Department of Pediatrics, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-8655, Japan., Sato K; Food Microbiology and Function Research Laboratory, Meiji Co., Ltd., 1-29-1, Nanakuni, Hachioji, Tokyo 192-0919, Japan.; Wellness Science Labs, Meiji Holdings Co., Ltd., 1-29-1, Nanakuni, Hachioji, Tokyo 192-0919, Japan., Jinno S; Food Microbiology and Function Research Laboratory, Meiji Co., Ltd., 1-29-1, Nanakuni, Hachioji, Tokyo 192-0919, Japan.; Wellness Science Labs, Meiji Holdings Co., Ltd., 1-29-1, Nanakuni, Hachioji, Tokyo 192-0919, Japan., Takahashi N; Department of Pediatrics, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-8655, Japan., Masumoto K; Department of Neonatology, Faculty of Medicine, Toho University, 6-11-1, Omorinishi, Ota-ku, Tokyo 143-8541, Japan., Yoda H; Department of Neonatology, Faculty of Medicine, Toho University, 6-11-1, Omorinishi, Ota-ku, Tokyo 143-8541, Japan., Shimizu T; Department of Pediatrics and Adolescent Medicine, Graduate School of Medicine, Juntendo University, 3-1-3, Hongo, Bunkyo-ku, Tokyo 113-8431, Japan.
المصدر: Nutrients [Nutrients] 2024 May 21; Vol. 16 (11). Date of Electronic Publication: 2024 May 21.
نوع المنشور: Journal Article; Observational Study
اللغة: English
بيانات الدورية: Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6643 (Electronic) Linking ISSN: 20726643 NLM ISO Abbreviation: Nutrients Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI Publishing
مواضيع طبية MeSH: Infant Formula*/chemistry , Feces*/chemistry , Palmitic Acid*/analysis , Triglycerides*/analysis , Triglycerides*/chemistry, Humans ; Infant, Newborn ; Female ; Male ; Infant Nutritional Physiological Phenomena ; Milk, Human/chemistry ; Japan
مستخلص: The binding ratio of palmitic acid (PA) at the sn-2 position of triacylglycerols in infant formulas is lower than that in breast milk, resulting in higher levels of fecal PA. Even if the ratio is increased to 40-50%, fecal PA levels in formula-fed infants remain higher than those in breast-fed infants. In Japan, infant formulas with 50% or more of PA bound to sn-2 (high sn-2 PA milk) are commercially available; however, their effects on PA excretion have not been investigated. Therefore, this observational study aimed to preliminarily evaluate whether the feeding volume of high sn-2 PA milk is significantly associated with fecal total/soaped PA levels in newborns. Infant formulas were classified as high (≥50% of PA bound to sn-2) or low sn-2 (<50%) PA milk. Associations between feeding volume of high or low sn-2 PA milk and fecal PA levels were evaluated using multiple regression analysis models. The results showed that the feeding volume of low sn-2 PA milk was positively associated with fecal total/soaped PA levels, while there was no significant association between those of high sn-2 PA milk and fecal total/soaped PA levels. Our preliminary study suggests that high sn-2 PA milk may reduce increased fecal PA levels in formula-fed newborns.
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فهرسة مساهمة: Keywords: breast milk; infant formula; sn-2 palmitate
المشرفين على المادة: 2V16EO95H1 (Palmitic Acid)
0 (Triglycerides)
تواريخ الأحداث: Date Created: 20240619 Date Completed: 20240619 Latest Revision: 20240924
رمز التحديث: 20240924
مُعرف محوري في PubMed: PMC11173637
DOI: 10.3390/nu16111558
PMID: 38892492
قاعدة البيانات: MEDLINE
الوصف
تدمد:2072-6643
DOI:10.3390/nu16111558