دورية أكاديمية

Comparing the safety and effectiveness of overlapping stents with flow diverters for unruptured vertebral artery dissecting aneurysms.

التفاصيل البيبلوغرافية
العنوان: Comparing the safety and effectiveness of overlapping stents with flow diverters for unruptured vertebral artery dissecting aneurysms.
المؤلفون: Kim HJ; Department of Neurology, Samsung Medical Center, Gangnam-gu, Seoul, Korea., Yang NR; Department of Neurosurgery, Ewha Womens University Mokdong Hospital, Seoul, Korea., Jee TK; Department of Neurosurgery, Samsung Medical Center, Gangnam-gu, Seoul, Korea., Yeon JY; Department of Neurosurgery, Samsung Medical Center, Gangnam-gu, Seoul, Korea., Kim KH; Department of Radiology, Samsung Medical Center, Gangnam-gu, Seoul, Korea., Kim JS; Department of Neurosurgery, Samsung Medical Center, Gangnam-gu, Seoul, Korea., Seo WK; Department of Neurology, Samsung Medical Center, Gangnam-gu, Seoul, Korea., Jeon P; Department of Radiology, Samsung Medical Center, Gangnam-gu, Seoul, Korea drpjeon@gmail.com.
المصدر: Journal of neurointerventional surgery [J Neurointerv Surg] 2024 Jun 24. Date of Electronic Publication: 2024 Jun 24.
Publication Model: Ahead of Print
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: BMJ Publishing Group Country of Publication: England NLM ID: 101517079 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1759-8486 (Electronic) Linking ISSN: 17598478 NLM ISO Abbreviation: J Neurointerv Surg Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : BMJ Publishing Group, c2009-
مستخلص: Background: Endovascular treatment for vertebral artery dissecting aneurysms (VADAs) includes overlapping stents and flow diverters. This study compared the safety and effectiveness of overlapping stents and flow diverters for unruptured VADAs.
Methods: We retrospectively enrolled patients with unruptured VADAs who underwent overlapping stents or flow diverters at two tertiary hospitals in South Korea. The primary clinical outcome was the occurrence of stroke. The primary angiographic outcomes (>12 months) were categorized as regression, no decrease in size, recanalization, or stent occlusion, of which only regression was defined as a favorable angiographic outcomes.
Results: Of the 146 patients with VADAs, 25 (17.1%) had flow diverters and 121 (82.9%) had overlapping stents. For the primary angiographic outcomes over 12 months, the rate of favorable angiographic outcomes for flow diverters was 81.8% and for overlapping stents (triple stents) was 98.8% (P=0.006). In the multivariale analysis, after adjusting for partially thrombosed aneurysms, aneurysm shape, non-dominant vessel, posterior inferior cerebellar artery involvement, and procedure type, overlapping stents (triple stents) was not associated with favorable angiographic outcomes compared with flow diverters (OR 7.040, 95% CI 0.549 to 90.294; P=0.134), but partially thrombosed aneurysms was inversely associated with favorable angiographic outcomes (OR 0.056, 95% CI 0.005 to 0.589; P=0.016). The primary clinical outcome followed up to the last angiography did not occur in all patients.
Conclusion: There was no difference in safety and effectiveness between overlapping stents and flow diverters in unruptured VADAs. Further endovascular treatment studies are needed regarding the association of partially thrombosed aneurysms with unfavorable angiographic outcomes.
Competing Interests: Competing interests: None declared.
(© Author(s) (or their employer(s)) 2024. No commercial re-use. See rights and permissions. Published by BMJ.)
فهرسة مساهمة: Keywords: Aneurysm; Dissection; Flow Diverter; Stent
تواريخ الأحداث: Date Created: 20240624 Latest Revision: 20240624
رمز التحديث: 20240625
DOI: 10.1136/jnis-2024-021762
PMID: 38914462
قاعدة البيانات: MEDLINE
الوصف
تدمد:1759-8486
DOI:10.1136/jnis-2024-021762