دورية أكاديمية

The 2017 Women's Health Initiative study and use of hormone therapy: an emulated repeated cross-sectional study.

التفاصيل البيبلوغرافية
العنوان: The 2017 Women's Health Initiative study and use of hormone therapy: an emulated repeated cross-sectional study.
المؤلفون: Chueh CH; Institute of Health and Welfare Policy, National Yang Ming Chiao Tung University, Taipei, Taiwan. chchueh.y@nycu.edu.tw., Ho PK; Institute of Health and Welfare Policy, National Yang Ming Chiao Tung University, Taipei, Taiwan., Li WH; Institute of Health and Welfare Policy, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Department of Obstetrics and Gynecology, Chen Hsin General Hospital, Taipei, Taiwan., Shiu MN; Institute of Health and Welfare Policy, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Department of Pharmacy, National Yang Ming Chiao Tung University, Taipei, Taiwan., Wang IT; Institute of Health and Welfare Policy, National Yang Ming Chiao Tung University, Taipei, Taiwan., Wen YW; Department of Biomedical Sciences, Chang Gung University, Taoyuan, Taiwan., Tsai YW; Institute of Health and Welfare Policy, National Yang Ming Chiao Tung University, Taipei, Taiwan. ywtsai@nycu.edu.tw.
المصدر: BMC public health [BMC Public Health] 2024 Jun 24; Vol. 24 (1), pp. 1674. Date of Electronic Publication: 2024 Jun 24.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100968562 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2458 (Electronic) Linking ISSN: 14712458 NLM ISO Abbreviation: BMC Public Health Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : BioMed Central, [2001-
مواضيع طبية MeSH: Women's Health*, Humans ; Female ; Cross-Sectional Studies ; Middle Aged ; Taiwan ; Estrogen Replacement Therapy/statistics & numerical data ; Menopause ; Hormone Replacement Therapy/statistics & numerical data
مستخلص: Background: Hormone therapy (HT) use among menopausal women declined after negative information from the 2002 Women's Health Initiative (WHI) HT study. The 2017 post-intervention follow-up WHI study revealed that HT did not increase long-term mortality. However, studies on the effects of the updated WHI findings are lacking. Thus, we assessed the impact of the 2017 WHI findings on HT use in Taiwan.
Methods: We identified 1,869,050 women aged 50-60 years, between June and December 2017, from health insurance claims data to compare HT use in the 3 months preceding and following September 2017. To address the limitations associated with interval-censored data, we employed an emulated repeated cross-sectional design. Using logistic regression analysis, we evaluated the impact of the 2017 WHI study on menopausal symptom-related outpatient visits and HT use. In a scenario analysis, we examined the impact of the 2002 trial on HT use to validate our study design.
Results: Study participants' baseline characteristics before and after the 2017 WHI study were not significantly different. Logistic regressions demonstrated that the 2017 study had no significant effect on outpatient visits for menopause-related symptoms or HT use among women with outpatient visits. The scenario analysis confirmed the negative impact of the 2002 WHI trial on HT use.
Conclusions: The 2017 WHI study did not demonstrate any impact on either menopause-related outpatient visits or HT use among middle-aged women in Taiwan. Our emulated cross-sectional study design may be employed in similar population-based policy intervention studies using interval-censored data.
(© 2024. The Author(s).)
References: JAMA. 2004 Jan 7;291(1):47-53. (PMID: 14709575)
Menopause. 2007 May-Jun;14(3 Pt 1):462-7. (PMID: 17237735)
Menopause. 2013 May;20(5):488-95. (PMID: 23615639)
Eur J Clin Pharmacol. 2006 Apr;62(4):307-10. (PMID: 16432715)
JAMA. 2002 Jul 17;288(3):321-33. (PMID: 12117397)
Maturitas. 2007 Nov 20;58(3):259-68. (PMID: 17920215)
Semin Reprod Med. 2010 Sep;28(5):404-21. (PMID: 20845239)
BJGP Open. 2022 Dec 20;6(4):. (PMID: 36216368)
JAMA. 2004 Apr 14;291(14):1701-12. (PMID: 15082697)
Climacteric. 2012 Feb;15(1):36-44. (PMID: 22168244)
Am J Med. 2005 Dec 19;118 Suppl 12B:14-24. (PMID: 16414323)
Arch Gen Psychiatry. 2010 Jun;67(6):598-607. (PMID: 20530009)
Maturitas. 2010 Mar;65(3):276-83. (PMID: 20018469)
Bone. 2001 Dec;29(6):517-22. (PMID: 11728921)
Sci Rep. 2023 Jan 11;13(1):539. (PMID: 36631522)
Menopause. 2019 Jul;26(7):741-749. (PMID: 30889086)
Maturitas. 2023 Sep;175:107787. (PMID: 37354643)
Control Clin Trials. 1998 Feb;19(1):61-109. (PMID: 9492970)
Maturitas. 2011 Mar;68(3):224-32. (PMID: 21295422)
Ann Intern Med. 2004 Feb 3;140(3):184-8. (PMID: 14757616)
Pharmacoepidemiol Drug Saf. 2007 Jan;16(1):17-27. (PMID: 16794994)
JAMA. 2017 Sep 12;318(10):927-938. (PMID: 28898378)
Int J Womens Health. 2015 Aug 20;7:773-82. (PMID: 26316824)
Post Reprod Health. 2019 Dec;25(4):183-190. (PMID: 31941377)
Medicina (Kaunas). 2019 Sep 18;55(9):. (PMID: 31540401)
Womens Health Issues. 2011 Mar-Apr;21(2):153-9. (PMID: 21168344)
BMC Womens Health. 2021 Oct 4;21(1):348. (PMID: 34607596)
فهرسة مساهمة: Keywords: Hormone therapy; Interval-censored data; Menopause; Repeated cross-sectional; Simple random sampling; Women’s Health Initiative
تواريخ الأحداث: Date Created: 20240624 Date Completed: 20240625 Latest Revision: 20240627
رمز التحديث: 20240627
مُعرف محوري في PubMed: PMC11194959
DOI: 10.1186/s12889-024-19089-2
PMID: 38914983
قاعدة البيانات: MEDLINE
الوصف
تدمد:1471-2458
DOI:10.1186/s12889-024-19089-2