دورية أكاديمية

Role of Diagnostic Nerve Blocks in the Goal-Oriented Treatment of Spasticity with Botulinum Toxin Type A: A Case-Control Study.

التفاصيل البيبلوغرافية
العنوان: Role of Diagnostic Nerve Blocks in the Goal-Oriented Treatment of Spasticity with Botulinum Toxin Type A: A Case-Control Study.
المؤلفون: Filippetti M; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, 37100 Verona, Italy., Tamburin S; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, 37100 Verona, Italy., Di Censo R; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, 37100 Verona, Italy., Adamo M; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, 37100 Verona, Italy., Manera E; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, 37100 Verona, Italy., Ingrà J; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, 37100 Verona, Italy., Mantovani E; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, 37100 Verona, Italy., Facciorusso S; Spasticity and Movement Disorders 'ReSTaRt' Unit, Physical Medicine and Rehabilitation Section, Policlinico Riuniti Hospital, University of Foggia, 71122 Foggia, Italy., Battaglia M; Physical and Rehabilitative Medicine, Department of Health Sciences, University of Eastern Piedmont 'A. Avogadro', 28100 Novara, Italy., Baricich A; Physical and Rehabilitative Medicine, Department of Health Sciences, University of Eastern Piedmont 'A. Avogadro', 28100 Novara, Italy., Santamato A; Spasticity and Movement Disorders 'ReSTaRt' Unit, Physical Medicine and Rehabilitation Section, Policlinico Riuniti Hospital, University of Foggia, 71122 Foggia, Italy., Smania N; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, 37100 Verona, Italy., Picelli A; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, 37100 Verona, Italy.; Canadian Advances in Neuro-Orthopedics for Spasticity Consortium (CANOSC), Kingston, ON K7K 1Z6, Canada.
المصدر: Toxins [Toxins (Basel)] 2024 Jun 03; Vol. 16 (6). Date of Electronic Publication: 2024 Jun 03.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101530765 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6651 (Electronic) Linking ISSN: 20726651 NLM ISO Abbreviation: Toxins (Basel) Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Basel : MDPI
مواضيع طبية MeSH: Nerve Block* , Botulinum Toxins, Type A*/therapeutic use , Muscle Spasticity*/diagnosis , Muscle Spasticity*/therapy , Neurological Rehabilitation*/methods, Humans ; Male ; Adult ; Middle Aged ; Aged ; Case-Control Studies ; Goals
مستخلص: The goal-setting process is pivotal in managing patients with disabling spasticity. This case-control study assessed the role of diagnostic nerve blocks in guiding the goal-setting process within goal-targeted treatment of spasticity with botulinum neurotoxin-A. In this case-control study, patients with disabling spasticity underwent either a goal-setting process based on the patient's needs and clinical evaluation (control group) or additional diagnostic nerve block procedures (case group). All enrolled patients underwent a focal treatment with botulinum neurotoxin-A injection and a 1-month follow-up evaluation during which goal achievement was quantified using the goal attainment scaling-light score system. Data showed a higher goal achievement rate in the case group (70%) than in the control group (40%). In conclusion, diagnostic nerve blocks may help guide the goal-setting process within goal-targeted treatment of spasticity with botulinum neurotoxin-A towards more realistic and achievable goals, thereby improving the outcomes of botulinum neurotoxin-A injection. Future studies should better explore the role of diagnostic nerve blocks to further personalize botulinum neurotoxin-A according to individual patients' preferences and requirements.
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فهرسة مساهمة: Keywords: botulinum neurotoxin-A; diagnostic nerve block; goal-setting process; neurorehabilitation; personalized treatment; spasticity
المشرفين على المادة: EC 3.4.24.69 (Botulinum Toxins, Type A)
تواريخ الأحداث: Date Created: 20240626 Date Completed: 20240627 Latest Revision: 20240629
رمز التحديث: 20240629
مُعرف محوري في PubMed: PMC11209555
DOI: 10.3390/toxins16060258
PMID: 38922151
قاعدة البيانات: MEDLINE
الوصف
تدمد:2072-6651
DOI:10.3390/toxins16060258