دورية أكاديمية
Diabetes and hypertension in elderly women: interactions between severity and failure to control inflammation.
| العنوان: | Diabetes and hypertension in elderly women: interactions between severity and failure to control inflammation. |
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| المؤلفون: | Lima PHB; Universidade Federal da Bahia, Instituto Multidisciplinar em Saúde, Campus Anísio Teixeira, Rua Rio de Contas, 58, Bloco 17, Lote 58, Candeias, 45029-094 Vitória da Conquista, BA, Brazil., Goncalves CV; Universidade Federal da Bahia, Instituto Multidisciplinar em Saúde, Campus Anísio Teixeira, Rua Rio de Contas, 58, Bloco 17, Lote 58, Candeias, 45029-094 Vitória da Conquista, BA, Brazil., Ribeiro IS; Universidade Federal do Sul da Bahia, Centro de Formação em Ciências da Saúde, Praça Joana Angélica, 58, São José, 45988-058 Teixeira de Freitas, BA, Brazil., Galantini MPL; Universidade Federal da Bahia, Instituto Multidisciplinar em Saúde, Campus Anísio Teixeira, Rua Rio de Contas, 58, Bloco 17, Lote 58, Candeias, 45029-094 Vitória da Conquista, BA, Brazil., Muniz IPR; Universidade Federal da Bahia, Instituto Multidisciplinar em Saúde, Campus Anísio Teixeira, Rua Rio de Contas, 58, Bloco 17, Lote 58, Candeias, 45029-094 Vitória da Conquista, BA, Brazil.; Universidade Estadual do Sudoeste da Bahia/UESB, Departamento de Ciências da Saúde, Campus Vitória da Conquista, Estr. Bem Querer, Km 04, 45031-300 Vitória da Conquista, BA, Brazil., Santos GS; Universidade Federal da Bahia, Instituto Multidisciplinar em Saúde, Campus Anísio Teixeira, Rua Rio de Contas, 58, Bloco 17, Lote 58, Candeias, 45029-094 Vitória da Conquista, BA, Brazil., Silva RAAD; Universidade Federal da Bahia, Instituto Multidisciplinar em Saúde, Campus Anísio Teixeira, Rua Rio de Contas, 58, Bloco 17, Lote 58, Candeias, 45029-094 Vitória da Conquista, BA, Brazil. |
| المصدر: | Anais da Academia Brasileira de Ciencias [An Acad Bras Cienc] 2024 Jun 24; Vol. 96 (3), pp. e20230844. Date of Electronic Publication: 2024 Jun 24 (Print Publication: 2024). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Academia Brasileira De Ciencias Country of Publication: Brazil NLM ID: 7503280 Publication Model: eCollection Cited Medium: Internet ISSN: 1678-2690 (Electronic) Linking ISSN: 00013765 NLM ISO Abbreviation: An Acad Bras Cienc Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Rio De Janeiro : Academia Brasileira De Ciencias |
| مواضيع طبية MeSH: | Hypertension* , Inflammation*/blood , Severity of Illness Index* , Biomarkers*/blood, Humans ; Female ; Aged ; Risk Factors ; Diabetes Mellitus ; Cytokines/blood ; Middle Aged ; Aged, 80 and over |
| مستخلص: | Elderly women are more susceptible to the development of chronic non-communicable diseases. Among these, diabetes mellitus (DM) and systemic arterial hypertension (SAH) stand out. This work aimed to carry out an expanded study on the interactions of anthropometric, biochemical and inflammatory parameters associated with the risk of severity in elderly women with hypertension and diabetes. The study involved the evaluation of 126 elderly women with hypertension and diabetes mellitus. The women were divided according disease severity (low, moderate, high and very high). Anthropometric data were collected by bioimpedance analysis. The inflammatory and biochemical data were obtained from volunteer blood samples. Waist circumference, waist circumference/height ratio, and systolic and diastolic pressures increased with severity. Biochemical marker levels increased with risk of severity, except HDLc. In the very high risk group, there was a higher IL-1β, IFN-γ and TNF-α production, however, lower IL-10 levels were observed. The very high risk group showed change values for the IL-10/IL-1β, IL-10/IL-17 and IL-10/TNF-α ratios. The results showed to be extensively altered in the very high risk group, where the inflammatory profile loses its responsiveness. This is the first study that shows an expanded view of the different parameters evaluated in elderly women with hypertension and diabetes. |
| المشرفين على المادة: | 0 (Biomarkers) 0 (Cytokines) |
| تواريخ الأحداث: | Date Created: 20240626 Date Completed: 20240626 Latest Revision: 20240626 |
| رمز التحديث: | 20240626 |
| DOI: | 10.1590/0001-3765202420230844 |
| PMID: | 38922257 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1678-2690 |
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| DOI: | 10.1590/0001-3765202420230844 |