دورية أكاديمية
Heteroleptic cobalt complex augments antifungal activity with fluconazole and causes membrane disruption in Candida albicans .
العنوان: | Heteroleptic cobalt complex augments antifungal activity with fluconazole and causes membrane disruption in Candida albicans . |
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المؤلفون: | Dar OA; Department of Chemistry, Jamia Millia Islamia, New Delhi 110025, India.; College of Pharmaceutical Sciences, Southwest University, Chongqing, China., Hashmi AA; Department of Chemistry, Jamia Millia Islamia, New Delhi 110025, India., Al-Bogami AS; Department of Chemistry, College of Science, University of Jeddah, 21589 Jeddah, Saudi Arabia. mwani@uj.edu.sa., Ahmad A; Clinical Microbiology and Infectious Diseases, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, 2193, South Africa. aijaz.ahmad@wits.ac.za.; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA., Wani MY; Department of Chemistry, College of Science, University of Jeddah, 21589 Jeddah, Saudi Arabia. mwani@uj.edu.sa. |
المصدر: | Dalton transactions (Cambridge, England : 2003) [Dalton Trans] 2024 Jul 16; Vol. 53 (28), pp. 11720-11735. Date of Electronic Publication: 2024 Jul 16. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101176026 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-9234 (Electronic) Linking ISSN: 14779226 NLM ISO Abbreviation: Dalton Trans Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: Cambridge, UK : Royal Society of Chemistry, c2003- |
مواضيع طبية MeSH: | Fluconazole*/pharmacology , Antifungal Agents*/pharmacology , Antifungal Agents*/chemistry , Antifungal Agents*/chemical synthesis , Candida albicans*/drug effects , Cobalt*/chemistry , Cobalt*/pharmacology , Coordination Complexes*/pharmacology , Coordination Complexes*/chemistry , Coordination Complexes*/chemical synthesis , Microbial Sensitivity Tests* , Cell Membrane*/drug effects, Drug Synergism ; Drug Resistance, Fungal/drug effects |
مستخلص: | Heteroleptic metal complexes containing Cu II , Co II , and Zn II , incorporating curcumin and a Schiff base ligand (L), were synthesized and characterized, and their antifungal activity was evaluated. Their antifungal activities were investigated individually and in combination with fluconazole. Utilizing various analytical techniques such as UV-Vis, FT-IR, NMR, ESI-MS, TGA-DTG, elemental analyses, conductance, and magnetic susceptibility measurements, complex C1 ([Cu(Cur)LCl(H |
المشرفين على المادة: | 8VZV102JFY (Fluconazole) 0 (Antifungal Agents) 3G0H8C9362 (Cobalt) 0 (Coordination Complexes) |
تواريخ الأحداث: | Date Created: 20240627 Date Completed: 20240716 Latest Revision: 20240716 |
رمز التحديث: | 20240716 |
DOI: | 10.1039/d4dt01209g |
PMID: | 38932585 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1477-9234 |
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DOI: | 10.1039/d4dt01209g |