دورية أكاديمية
Behavioural, autonomic, and neural responsivity in depersonalisation-derealisation disorder: A systematic review of experimental evidence.
| العنوان: | Behavioural, autonomic, and neural responsivity in depersonalisation-derealisation disorder: A systematic review of experimental evidence. |
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| المؤلفون: | Millman LSM; Department of Psychological Medicine, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, United Kingdom., Huang X; Department of Psychological Medicine, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, United Kingdom., Wainipitapong S; Department of Global Health and Social Medicine, King's College London, London, United Kingdom; Department of Psychiatry and Center of Excellence in Transgender Health, King Chulalongkorn Memorial Hospital and Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand., Medford N; Lishman Unit, Bethlem Royal Hospital, London, United Kingdom., Pick S; Department of Psychological Medicine, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, United Kingdom. Electronic address: susannah.pick@kcl.ac.uk. |
| المصدر: | Neuroscience and biobehavioral reviews [Neurosci Biobehav Rev] 2024 Aug; Vol. 163, pp. 105783. Date of Electronic Publication: 2024 Jun 27. |
| نوع المنشور: | Systematic Review; Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Pergamon Press Country of Publication: United States NLM ID: 7806090 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7528 (Electronic) Linking ISSN: 01497634 NLM ISO Abbreviation: Neurosci Biobehav Rev Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: New York Ny : Pergamon Press Original Publication: Fayetteville, N. Y., ANKHO International Inc. |
| مواضيع طبية MeSH: | Depersonalization*/physiopathology , Autonomic Nervous System*/physiopathology, Humans ; Emotional Regulation/physiology |
| مستخلص: | Depersonalisation-derealisation disorder (DDD) is characterised by distressing experiences of separation from oneself and/or one's surroundings, potentially resulting from alterations in affective, cognitive, and physiological functions. This systematic review aimed to synthesise current experimental evidence of relevance to proposed mechanisms underlying DDD, to appraise existing theoretical models, and to inform future research and theoretical developments. Studies were included if they tested explicit hypotheses in DDD samples, with experimental manipulations of at least one independent variable, alongside behavioural, subjective, neurological, affective and/or physiological dependent variables. Some evidence for diminished subjective responsivity to aversive images and sounds, and hyperactivation in neurocircuits associated with emotional regulation when viewing aversive images emerged, corroborating neurobiological models of DDD. Inconsistencies were present regarding behavioural and autonomic responsivity to facial expressions, emotional memory, and self-referential processing. Common confounds included small sample sizes, medication, and comorbidities. Alterations in affective reactivity and regulation appear to be present in DDD; however, further research employing more rigorous research designs is required to provide stronger evidence for these possible mechanisms. (Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Autonomic; Behavioural; Depersonalisation-derealisation disorder; Dissociation; Emotional regulation; Experimental; Neurobiological |
| تواريخ الأحداث: | Date Created: 20240629 Date Completed: 20240712 Latest Revision: 20240715 |
| رمز التحديث: | 20240716 |
| DOI: | 10.1016/j.neubiorev.2024.105783 |
| PMID: | 38944228 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1873-7528 |
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| DOI: | 10.1016/j.neubiorev.2024.105783 |