دورية أكاديمية
Towards precision cancer medicine for Aboriginal and Torres Strait Islander cancer health equity.
العنوان: | Towards precision cancer medicine for Aboriginal and Torres Strait Islander cancer health equity. |
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المؤلفون: | Clark Adnyamathanha JR; Telethon Kids Institute, Adelaide, SA.; Australian National University, Canberra, ACT., Buck Kamilaroi J; Telethon Kids Cancer Centre, Telethon Kids Institute, Perth, WA.; Centre for Child Health Research, University of Western Australia, Perth, WA., Richards-Satour Adnyamathanha And Barngarla A; Telethon Kids Institute, Adelaide, SA., Lyons Jaadwa L; Telethon Kids Institute, Adelaide, SA., Brown Yuin A; Telethon Kids Institute, Adelaide, SA.; National Centre for Indigenous Genomics, Australian National University, Canberra, ACT. |
المصدر: | The Medical journal of Australia [Med J Aust] 2024 Jul 01; Vol. 221 (1), pp. 68-73. |
نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't; Review |
اللغة: | English |
بيانات الدورية: | Publisher: Australasian Medical Publishing Co Country of Publication: Australia NLM ID: 0400714 Publication Model: Print Cited Medium: Internet ISSN: 1326-5377 (Electronic) Linking ISSN: 0025729X NLM ISO Abbreviation: Med J Aust Subsets: MEDLINE |
أسماء مطبوعة: | Publication: Original Publication: Sydney : Australasian Medical Pub. Co. |
مواضيع طبية MeSH: | Australian Aboriginal and Torres Strait Islander Peoples* , Health Equity* , Health Services, Indigenous*/organization & administration , Neoplasms*/ethnology , Neoplasms*/therapy , Neoplasms*/genetics , Precision Medicine*/methods, Humans ; Australia ; Genomics ; Health Services Accessibility ; Healthcare Disparities/ethnology |
مستخلص: | Delivering cancer control at scale for Aboriginal and Torres Strait Islander communities is a national priority that requires Aboriginal and Torres Strait Islander leadership and codesign, as well as significant involvement of the Aboriginal community-controlled health sector. The unique genomic variation observed among Aboriginal and Torres Strait Islander peoples may have implications for standard and precision medicine. Yet, Aboriginal and Torres Strait Islander peoples are absent from, or under-represented within, human reference genome resources, genomic studies, cancer studies, cancer cell lines, patient-derived xenografts and cancer clinical trials. Genomics-guided precision cancer medicine offers an opportunity to reduce cancer health disparities experienced by Aboriginal and Torres Strait Islander peoples through personalising prevention, diagnosis, treatment and long term management. Here, we describe what is required to ensure that Aboriginal and Torres Strait Islander peoples can receive the benefits of precision cancer medicine. Equity of access to care, an Aboriginal and Torres Strait Islander cancer workforce, and appropriate genome reference resources are important for safe and effective cancer medicine. Building Indigenous data sovereignty principles and Aboriginal and Torres Strait Islander governance into research is required to protect Aboriginal and Torres Strait Islander rights and collective interests. Aboriginal and Torres Strait Islander community engagement should be undertaken to develop an understanding of the unique cultural and ethical considerations for precision cancer research. Local and national genomic health research guidelines are needed to define a consensus best practice in genomics research with Aboriginal and Torres Strait Islander peoples. (© 2024 The Author(s). Medical Journal of Australia published by John Wiley & Sons Australia, Ltd on behalf of AMPCo Pty Ltd.) |
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فهرسة مساهمة: | Keywords: Cancer; Indigenous health |
تواريخ الأحداث: | Date Created: 20240701 Date Completed: 20240701 Latest Revision: 20240813 |
رمز التحديث: | 20240814 |
DOI: | 10.5694/mja2.52346 |
PMID: | 38946636 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1326-5377 |
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DOI: | 10.5694/mja2.52346 |