دورية أكاديمية
أعرض في EDS

Evasion of wheat resistance gene Lr15 recognition by the leaf rust fungus is attributed to the coincidence of natural mutations and deletion in AvrLr15 gene.

التفاصيل البيبلوغرافية
العنوان: Evasion of wheat resistance gene Lr15 recognition by the leaf rust fungus is attributed to the coincidence of natural mutations and deletion in AvrLr15 gene.
المؤلفون: Cui Z; College of Plant Protection, Hebei Agricultural University/Technological Innovation Center for Biological Control of Crop Diseases and Insect Pests of Hebei Province, Baoding, Hebei, China., Shen S; College of Plant Protection, Hebei Agricultural University/Technological Innovation Center for Biological Control of Crop Diseases and Insect Pests of Hebei Province, Baoding, Hebei, China., Meng L; College of Plant Protection, Hebei Agricultural University/Technological Innovation Center for Biological Control of Crop Diseases and Insect Pests of Hebei Province, Baoding, Hebei, China., Sun X; The State Key Laboratory of North China Crop Improvement and Regulation, College of Horticulture, Baoding, Hebei, China., Jin Y; College of Plant Protection, Hebei Agricultural University/Technological Innovation Center for Biological Control of Crop Diseases and Insect Pests of Hebei Province, Baoding, Hebei, China., Liu Y; College of Plant Protection, Hebei Agricultural University/Technological Innovation Center for Biological Control of Crop Diseases and Insect Pests of Hebei Province, Baoding, Hebei, China., Liu D; College of Plant Protection, Hebei Agricultural University/Technological Innovation Center for Biological Control of Crop Diseases and Insect Pests of Hebei Province, Baoding, Hebei, China., Ma L; The State Key Laboratory of North China Crop Improvement and Regulation, College of Horticulture, Baoding, Hebei, China., Wang H; College of Plant Protection, Hebei Agricultural University/Technological Innovation Center for Biological Control of Crop Diseases and Insect Pests of Hebei Province, Baoding, Hebei, China.
المصدر: Molecular plant pathology [Mol Plant Pathol] 2024 Jul; Vol. 25 (7), pp. e13490.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Blackwell Science in collaboration with the British Society of Plant Pathology Country of Publication: England NLM ID: 100954969 Publication Model: Print Cited Medium: Internet ISSN: 1364-3703 (Electronic) Linking ISSN: 13643703 NLM ISO Abbreviation: Mol Plant Pathol Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Oxford, UK : Blackwell Science in collaboration with the British Society of Plant Pathology, c2000-
مواضيع طبية MeSH: Triticum*/microbiology , Triticum*/genetics , Triticum*/immunology , Plant Diseases*/microbiology , Plant Diseases*/genetics , Plant Diseases*/immunology , Disease Resistance*/genetics , Puccinia*/pathogenicity, Fungal Proteins/genetics ; Fungal Proteins/metabolism ; Genes, Plant ; Virulence/genetics ; Mutation/genetics ; Plant Proteins/genetics ; Plant Proteins/metabolism ; Basidiomycota/pathogenicity ; Basidiomycota/genetics ; Plant Leaves/microbiology ; Plant Leaves/immunology ; Cell Death ; Sequence Deletion/genetics
مستخلص: Employing race-specific resistance genes remains an effective strategy to protect wheat from leaf rust caused by Puccinia triticina (Pt) worldwide, while the newly emerged Pt races, owing to rapid genetic evolution, frequently overcome the immune response delivered by race-specific resistance genes. The molecular mechanisms underlying the newly evolved virulence Pt pathogen remain unknown. Here, we identified an avirulence protein AvrLr15 from Pt that induced Lr15-dependent immune responses. Heterologously produced AvrLr15 triggered pronounced cell death in Lr15-isogenic wheat leaves. AvrLr15 contains a functional signal peptide, localized to the plant nucleus and cytosol and can suppress BAX-induced cell death. Evasion of Lr15-mediated resistance in wheat was associated with a deletion and point mutations of amino acids in AvrLr15 rather than AvrLr15 gene loss in the Lr15-breaking Pt races, implying that AvrLr15 is required for the virulence function of Pt. Our findings identified the first molecular determinant of wheat race-specific immunity and facilitated the identification of the first AVR/R gene pair in the Pt-wheat pathosystem, which will provide a molecular marker to monitor natural Pt populations and guide the deployment of Lr15-resistant wheat cultivars in the field.
(© 2024 The Author(s). Molecular Plant Pathology published by British Society for Plant Pathology and John Wiley & Sons Ltd.)
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معلومات مُعتمدة: NCCIR2023ZZ-10 State Key Laboratory of North China Crop Improvement and Regulation; 31501623 National Natural Science Foundation of China; 32172384 National Natural Science Foundation of China
فهرسة مساهمة: Keywords: Puccinia triticina; AvrLr15; avirulence gene
المشرفين على المادة: 0 (Fungal Proteins)
0 (Plant Proteins)
SCR Organism: Puccinia triticina
تواريخ الأحداث: Date Created: 20240702 Date Completed: 20240702 Latest Revision: 20240704
رمز التحديث: 20240704
مُعرف محوري في PubMed: PMC11217590
DOI: 10.1111/mpp.13490
PMID: 38952297
قاعدة البيانات: MEDLINE
الوصف
تدمد:1364-3703
DOI:10.1111/mpp.13490