دورية أكاديمية
Radioligand Therapy in Lymphoma: Past, Present, and Future.
| العنوان: | Radioligand Therapy in Lymphoma: Past, Present, and Future. |
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| المؤلفون: | Almeida LS; Division of Nuclear Medicine, University of Campinas (UNICAMP), Rua Vital Brasil 251, Campinas, 13083-888, Brazil; Department of Diagnostic Imaging (Radiology) and Nuclear Medicine, University Hospital San Pedro and Centre for Biomedical Research of La Rioja, Outro Pl. San Pedro, 3, 26006 Logroño, La Rioja, España., Delgado Bolton RC; Department of Diagnostic Imaging (Radiology) and Nuclear Medicine, University Hospital San Pedro and Centre for Biomedical Research of La Rioja, Outro Pl. San Pedro, 3, 26006 Logroño, La Rioja, España; Servicio Cántabro de Salud, Av Herrera Oria, s/n, 39011 Santander, Cantabria, España., Heringer VC; Division of Nuclear Medicine, University of Campinas (UNICAMP), Rua Vital Brasil 251, Campinas, 13083-888, Brazil., de Souza Medina S; Division of Hematology, Department of Internal Medicine, Faculty of Medical Sciences, Campinas University, R. Carlos Chagas, 480 - Cidade Universitária, Campinas, SP, 13083-878, Brazil., Etchebehere E; Division of Nuclear Medicine, University of Campinas (UNICAMP), Rua Vital Brasil 251, Campinas, 13083-888, Brazil. Electronic address: elba@unicamp.br. |
| المصدر: | PET clinics [PET Clin] 2024 Oct; Vol. 19 (4), pp. 475-494. Date of Electronic Publication: 2024 Jul 04. |
| نوع المنشور: | Historical Article; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Saunders Country of Publication: United States NLM ID: 101260152 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-9809 (Electronic) Linking ISSN: 15568598 NLM ISO Abbreviation: PET Clin Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Philadelphia : Elsevier Saunders, c2006- |
| مواضيع طبية MeSH: | Lymphoma*/radiotherapy , Lymphoma*/diagnostic imaging , Radioimmunotherapy*/methods , Radiopharmaceuticals*/therapeutic use, Humans ; Antibodies, Monoclonal/therapeutic use ; History, 20th Century ; History, 21st Century ; Iodine Radioisotopes/therapeutic use ; Yttrium Radioisotopes/therapeutic use |
| مستخلص: | In the1980s, radiolabeled cells helped understand the pathology of hemato-oncology. In the 1990s, preclinical trials evaluated radiolabeled immunotherapy with monoclonal antibodies (MoAbs) such as anti-CD20 agents labeled with Iodine-131 (Bexxar) or Yttrium-90 (Zevalin). Due to the safe and durable responses of radiolabeled MoAbs, the Food and Drug Administration approved these agents in the 2000s. Despite radioimmunotherapy's long journey, its application has recently decreased. This review will discuss the historical timeline of radioimmunotherapy, debate on advantages and difficulties, and explore trials. We will examine future directions of radioligand therapy in hemato-oncology, considering emerging molecules that may become the next theragnostic trend. Competing Interests: Disclosure L.S. Almeida: This study was supported, in part, by the CapesPRInt (Institutional Program for Internationalization) scholarship given to Ludmila Santiago Almeida (reference number: PRINT – 88887.716546/2022-00) by the CAPES (Coordination for the Improvement of Higher Education Personnel) Foundation, within the Brazilian Ministry of Education, Government of Brazil (ludsantiagoalmeida@gmail.com). R.C. Delgado Bolton: rbiolton@gmail.com—Nothing to declare. V.C. Heringer: drv.cabralheringer@gmail.com—Nothing to declare. S. de Souza Medina: souzamedina@gmail.com—Nothing to declare. EE: elba@unicamp.br—CEPID – CancerThera project (FAPESP # 2021/10,265–8) partly supports this study. (Copyright © 2024 Elsevier Inc. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Immunotherapy; Lymphoma; Radioligand; Theranostics; Therapy |
| المشرفين على المادة: | 0 (Antibodies, Monoclonal) 0 (Iodine Radioisotopes) 0 (Radiopharmaceuticals) 0 (Yttrium Radioisotopes) |
| تواريخ الأحداث: | Date Created: 20240705 Date Completed: 20240830 Latest Revision: 20240905 |
| رمز التحديث: | 20240905 |
| DOI: | 10.1016/j.cpet.2024.05.003 |
| PMID: | 38969564 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1879-9809 |
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| DOI: | 10.1016/j.cpet.2024.05.003 |