دورية أكاديمية

Comparative efficacy and safety of Chinese patent medicines of iron deficiency anemia during pregnancy: A network meta-analysis.

التفاصيل البيبلوغرافية
العنوان: Comparative efficacy and safety of Chinese patent medicines of iron deficiency anemia during pregnancy: A network meta-analysis.
المؤلفون: Zou JC; School of Chinese Medicine, Weifang Medical University, Weifang 261053, Shandong Province, China., Jia XL; School of Chinese Medicine, Weifang Medical University, Weifang 261053, Shandong Province, China., Wang HX; Traditional Chinese Medicine Department, Affiliated Hospital of Weifang Medical University, Weifang 261031, Shandong Province, China. wsy852893@163.com., Su YJ; Traditional Chinese Medicine Department, Affiliated Hospital of Weifang Medical University, Weifang 261031, Shandong Province, China., Zhu JY; Traditional Chinese Medicine Department, Affiliated Hospital of Weifang Medical University, Weifang 261031, Shandong Province, China.
المصدر: World journal of clinical cases [World J Clin Cases] 2024 Jun 26; Vol. 12 (18), pp. 3515-3528.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Baishideng Publishing Group Country of Publication: United States NLM ID: 101618806 Publication Model: Print Cited Medium: Print ISSN: 2307-8960 (Print) Linking ISSN: 23078960 NLM ISO Abbreviation: World J Clin Cases Subsets: PubMed not MEDLINE
أسماء مطبوعة: Publication: 2014-: Pleasanton, CA : Baishideng Publishing Group
Original Publication: Hong Kong, China : Baishideng Publishing Group Co., Limited, [2013]-
مستخلص: Background: Iron deficiency anemia (IDA) is a prevalent nutritional disorder during pregnancy. Clinical studies indicate that incorporating Chinese patent medicines (CPMs) with oral iron (OI) in treating IDA in pregnancy can reduce adverse effects and improve clinical outcomes. Nonetheless, the comparative efficacy of different CPMs remains unclear.
Aim: To assess the safety and effectiveness of different CPMs for treating IDA during pregnancy using network meta-analysis.
Methods: We conducted a search for randomized controlled trials (RCTs) that combined CPM and OI for IDA treatment in pregnancy, spanning from 2013 to the present. Data analysis was performed using Rev Man 5.3 and Stata 14.0 on literature that satisfied the quality criteria.
Results: The analysis included 45 RCTs, encompassing 4422 pregnant patients with IDA. Six CPMs were examined, including Shengxuebao Mixture, Shengxuening Tablets (SXN), Yiqi Weixue CPMs (YQWX), Jianpi Shengxue CPMs (JPSX), Yiqi Buxue Tablets, and Compound Hongyi Buxue Oral Liquid (FFHY). Findings indicated that FFHY + OI significantly improved the clinical effective rate. SXN + OI was most effective in boosting red blood cells counts and hemoglobin levels. YQWX + OI showed superior results in improving serum ferritin, and SXN + OI was most effective in increasing serum iron levels. JPSX + OI was optimal in reducing adverse pregnancy outcomes, while YQBX + OI effectively minimized adverse events. A cluster analysis suggested that SXN + OI could be the potentially optimal therapeutic regimen for IDA in pregnancy.
Conclusion: This study demonstrates that the combination of OI with CPMs offers better outcomes than OI alone. Based on clinical efficacy and other measured outcomes, SXN + OI emerges as the most effective treatment modality for improving the health of pregnant patients with IDA.
Competing Interests: Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
(©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.)
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فهرسة مساهمة: Keywords: Chinese patent medicine; Compound Hongyi Buxue Oral Liquid; Jianpi Shengxue Chinese patent medicines; Network meta-analysis; Shengxuebao Mixture; Shengxuening Tablets; Yiqi Buxue Tablets; Yiqi Weixue Chinese patent medicines
تواريخ الأحداث: Date Created: 20240710 Latest Revision: 20240711
رمز التحديث: 20240711
مُعرف محوري في PubMed: PMC11229903
DOI: 10.12998/wjcc.v12.i18.3515
PMID: 38983402
قاعدة البيانات: MEDLINE
الوصف
تدمد:2307-8960
DOI:10.12998/wjcc.v12.i18.3515