دورية أكاديمية
Diagnosis and management of a herpes nipple infection that resulted in neonatal HSV encephalitis.
| العنوان: | Diagnosis and management of a herpes nipple infection that resulted in neonatal HSV encephalitis. |
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| المؤلفون: | Stokes S; Obstetrics and Gynecology, Augusta University Medical Center, Augusta, Georgia, USA stephaniestokes2020@gmail.com., Zahler-Miller C; Obstetrics and Gynecology, Augusta University Medical Center, Augusta, Georgia, USA., Dunn K; Obstetrics and Gynecology, Augusta University Medical Center, Augusta, Georgia, USA. |
| المصدر: | BMJ case reports [BMJ Case Rep] 2024 Jul 10; Vol. 17 (7). Date of Electronic Publication: 2024 Jul 10. |
| نوع المنشور: | Journal Article; Case Reports |
| اللغة: | English |
| بيانات الدورية: | Publisher: BMJ Pub. Group Country of Publication: England NLM ID: 101526291 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-790X (Electronic) Linking ISSN: 1757790X NLM ISO Abbreviation: BMJ Case Rep Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: London : BMJ Pub. Group |
| مواضيع طبية MeSH: | Antiviral Agents*/therapeutic use , Antiviral Agents*/administration & dosage , Acyclovir*/therapeutic use , Acyclovir*/administration & dosage , Herpes Simplex*/diagnosis , Herpes Simplex*/drug therapy , Nipples* , Herpesvirus 1, Human*/isolation & purification , Encephalitis, Herpes Simplex*/diagnosis , Encephalitis, Herpes Simplex*/drug therapy, Humans ; Female ; Infant, Newborn ; Valacyclovir/therapeutic use ; Valacyclovir/administration & dosage ; Pregnancy Complications, Infectious/diagnosis ; Adult ; Pregnancy ; Infectious Disease Transmission, Vertical ; Valine/analogs & derivatives ; Valine/therapeutic use ; Valine/administration & dosage ; Breast Feeding |
| مستخلص: | We present a case of a primigravida in her 30s who had a caesarean delivery of dichorionic diamniotic twins at 33 weeks of gestation. Her postpartum course was complicated by a herpes simplex virus (HSV) infection of her nipple, found after her neonates were diagnosed with HSV encephalitis. She was evaluated at her 3-week postpartum visit and reported that her neonates were concurrently admitted to the neonatal intensive care unit with disseminated neonatal HSV-1. The patient and her partner were in a monogamous relationship with no known history of HSV. Physical examination demonstrated a vertical fissure on the face of her right nipple and a small cluster of vesicles on her left hand. PCR swabs of the lesions were positive for HSV-1 at both locations. The patient was started on oral valacyclovir 1000 mg two times per day, topical acyclovir ointment applied 4-6 times per day and mupirocin ointment applied 3 times per day to her breast with resolution of her breast lesions. She was able to continue expressing her breastmilk with the help of a pump and then resumed breastfeeding once her infection was cleared. Her infants recovered after prolonged parenteral antiviral therapy with age-appropriate development at follow-up. Competing Interests: Competing interests: None declared. (© BMJ Publishing Group Limited 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.) |
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| فهرسة مساهمة: | Keywords: Herpes simplex virus; Infant nutrition (including breastfeeding); Infections; Neonatal intensive care; Skin |
| المشرفين على المادة: | 0 (Antiviral Agents) X4HES1O11F (Acyclovir) MZ1IW7Q79D (Valacyclovir) HG18B9YRS7 (Valine) |
| SCR Disease Name: | Neonatal herpes |
| تواريخ الأحداث: | Date Created: 20240711 Date Completed: 20240711 Latest Revision: 20240726 |
| رمز التحديث: | 20240726 |
| مُعرف محوري في PubMed: | PMC11268031 |
| DOI: | 10.1136/bcr-2023-257150 |
| PMID: | 38991567 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1757-790X |
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| DOI: | 10.1136/bcr-2023-257150 |