دورية أكاديمية
أعرض في EDS

Changes in the outer nuclear layer and choroidal vascularity during the manifest and quiescent phases of acute central serous chorioretinopathy.

التفاصيل البيبلوغرافية
العنوان: Changes in the outer nuclear layer and choroidal vascularity during the manifest and quiescent phases of acute central serous chorioretinopathy.
المؤلفون: Lim G; Department of Ophthalmology, College of Medicine, Chungbuk National University Hospital, Chungbuk National University, 776, Sunhwan-1-Ro, Seowon-Gu, Cheongju, 28644, Korea., Kim KT; Department of Ophthalmology, College of Medicine, Chungbuk National University Hospital, Chungbuk National University, 776, Sunhwan-1-Ro, Seowon-Gu, Cheongju, 28644, Korea., Kim DY; Seoul Top Eye Center, Cheongju, Korea., Chae JB; Seoul Top Eye Center, Cheongju, Korea., Seo EJ; Department of Ophthalmology, College of Medicine, Chungbuk National University Hospital, Chungbuk National University, 776, Sunhwan-1-Ro, Seowon-Gu, Cheongju, 28644, Korea. seoej1@gmail.com.
المصدر: Scientific reports [Sci Rep] 2024 Jul 11; Vol. 14 (1), pp. 16057. Date of Electronic Publication: 2024 Jul 11.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : Nature Publishing Group, copyright 2011-
مواضيع طبية MeSH: Central Serous Chorioretinopathy*/pathology , Central Serous Chorioretinopathy*/diagnostic imaging , Choroid*/blood supply , Choroid*/pathology , Choroid*/diagnostic imaging , Visual Acuity* , Tomography, Optical Coherence*/methods, Humans ; Male ; Female ; Middle Aged ; Adult ; Retrospective Studies ; Acute Disease ; Fluorescein Angiography
مستخلص: To investigate alteration of outer nuclear layer (ONL) and choroidal vascularity index (CVI) in different status of central serous chorioretinopathy (CSC). A retrospective review of 65 CSC eyes with subretinal fluid (manifest CSC) and 40 control eyes was conducted in a single tertiary university hospital. Differences in best-corrected visual acuity (BCVA), ONL, and CVI were compared. CVI was assessed both in the entire choroid (CVI-EC) and around the 1500 μm leakage area (CVI-1500). Measurements were repeated after the subretinal fluid resorption (quiescent CSC), and compared. CSC eyes showed worse BCVA, thinner ONL and greater CVI than controls. Quiescent CSC showed a recovery of ONL compared to the manifest CSC, along with the BCVA improvement. The resolution of the CSC revealed a decrease across all three choroidal areas (total, stromal and luminal), with a more pronounced reduction in the stromal than in the luminal choroidal area, leading to an increase in the CVI. This phenomenon was shown in both CVI-EC and CVI-1500. Conclusively, ONL thickness can be used as a quantitative biomarker for photoreceptor function in CSC. Increased CVI may reflect a disease activity. The stromal choroidal area is particularly sensitive in illustrating leakage from the choroidal vasculature.
(© 2024. The Author(s).)
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فهرسة مساهمة: Keywords: Central serous chorioretinopathy; Choroid; Optical coherence tomography; Photoreceptor cells; Subretinal fluid
تواريخ الأحداث: Date Created: 20240711 Date Completed: 20240711 Latest Revision: 20240731
رمز التحديث: 20240731
مُعرف محوري في PubMed: PMC11239832
DOI: 10.1038/s41598-024-67012-x
PMID: 38992103
قاعدة البيانات: MEDLINE
الوصف
تدمد:2045-2322
DOI:10.1038/s41598-024-67012-x