دورية أكاديمية
Pathologic and Short-Term Oncologic Outcomes of Prostate Cancer Patients Following Transvesical Robot-Assisted Radical Prostatectomy.
| العنوان: | Pathologic and Short-Term Oncologic Outcomes of Prostate Cancer Patients Following Transvesical Robot-Assisted Radical Prostatectomy. |
|---|---|
| المؤلفون: | Benidir T; Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH., Ferguson EL; Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH., Lone Z; Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH., Soputro NA; Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH., Ramos-Carpinteyro R; Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH., Weight CJ; Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH., Kaouk J; Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH. Electronic address: kaoukj@ccf.org. |
| المصدر: | Urologic oncology [Urol Oncol] 2024 Jul 13. Date of Electronic Publication: 2024 Jul 13. |
| Publication Model: | Ahead of Print |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: United States NLM ID: 9805460 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2496 (Electronic) Linking ISSN: 10781439 NLM ISO Abbreviation: Urol Oncol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2003- : Philadelphia, PA : Elsevier Original Publication: New York, NY : Elsevier Science, |
| مستخلص: | Purpose: To study the pathologic and short-term oncological and survival outcomes following Transvesical Single-Port Robot-Assisted Radical Prostatectomy. Materials and Methods: A retrospective review was performed on prospectively collected data on 169 patients with low and intermediate-risks prostate cancer, who either underwent Single-Port Transvesical or Multi-Port Transperitoneal Radical Prostatectomy by a single surgeon between 2015 and 2022. Preoperative clinicopathologic characteristics, as well as final histopathology outcomes, were compared. Univariate Cox proportional hazard analysis was used to evaluate the impact of the surgical approach on biochemical recurrence-free survival within 12 months. Results: Single-Port Transvesical and Multi-Port Transperitoneal Robotic Radical Prostatectomy were completed in 85 and 84 patients, respectively. Preoperative clinicopathologic features were similar between the 2 groups. In terms of histopathology outcomes, the 2 groups had identical final Gleason Grades, T stage, as well as the rates of adverse pathological features and positive surgical margins (P = >0.05). Despite the lower median number of nodes in the single-port cohort of 2 (0-5) compared to 6 (4-9) in the multi-port cohort (P = <0.001), there remained no statistically significant difference in the rates of lymph node invasion (P = 0.08). At a median follow-up of 12 months, there were no differences in the biochemical recurrence-free survival rates among both groups (P = 0.38). Univariate Cox proportional hazard analysis did not consider surgical approach to be an independent predictor of biochemical recurrence (HR 0.53, 95%CI 0.13-2.23, P = 0.39). Conclusion: In well-selected patients, single-port transvesical robotic radical prostatectomy provided a similar short-term oncologic control as the multi-port approach with similar surgical margin status and 1-year biochemical recurrence rates. Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Non-Financial Conflict of Interest: Jihad H Kaouk: Speaker for Intuitive Surgical, Inc., Consultants for VTI, Method AI, and Endoquest Robotics. The remaining authors (Tarik Benidir, Ethan L Ferguson, Zaeem Lone, Nicolas A Soputro, Roxana Ramos-Carpinteyro, and Christopher J Weight) have no known competing personal relationships, financial or non-financial interests to disclose (Copyright © 2024 Elsevier Inc. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Oncological outcomes; Radical prostatectomy; Robotic surgery; Single-port |
| تواريخ الأحداث: | Date Created: 20240714 Latest Revision: 20240714 |
| رمز التحديث: | 20240715 |
| DOI: | 10.1016/j.urolonc.2024.06.007 |
| PMID: | 39004529 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder كن أول من يترك تعليقا!