دورية أكاديمية
أعرض في EDS

Prevalence and associated factors of postoperative suxamethonium-induced myalgia in surgical patients at Debre Tabor Comprehensive Specialized Hospital Ethiopia: a cross-sectional study.

التفاصيل البيبلوغرافية
العنوان: Prevalence and associated factors of postoperative suxamethonium-induced myalgia in surgical patients at Debre Tabor Comprehensive Specialized Hospital Ethiopia: a cross-sectional study.
المؤلفون: Chekol B; Department of Anesthesia, School of Medicine, College of Health Science, Debre Tabor University, PO.Box: 272, Debre Tabor, Ethiopia. basechek06@gmail.com., Zurbachew N; Department of Anesthesia, School of Medicine, College of Health Science, Debre Tabor University, PO.Box: 272, Debre Tabor, Ethiopia., Mekete G; Department of Anesthesia, School of Medicine, College of Health Science, Debre Tabor University, PO.Box: 272, Debre Tabor, Ethiopia., Bayuh E; Department of Anesthesia, School of Medicine, College of Health Science, Debre Tabor University, PO.Box: 272, Debre Tabor, Ethiopia., Teshome D; Department of Anesthesia, School of Medicine, College of Health Science, Debre Tabor University, PO.Box: 272, Debre Tabor, Ethiopia.
المصدر: Scientific reports [Sci Rep] 2024 Jul 17; Vol. 14 (1), pp. 16552. Date of Electronic Publication: 2024 Jul 17.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : Nature Publishing Group, copyright 2011-
مواضيع طبية MeSH: Succinylcholine*/adverse effects , Myalgia*/epidemiology , Myalgia*/chemically induced , Postoperative Complications*/epidemiology , Postoperative Complications*/etiology, Humans ; Male ; Female ; Cross-Sectional Studies ; Adult ; Prevalence ; Ethiopia/epidemiology ; Middle Aged ; Young Adult ; Risk Factors ; Adolescent ; Anesthesia, General/adverse effects ; Hospitals, Special ; Aged
مستخلص: Suxamethonium is considered by many to be the best drug for providing ideal intubating conditions, short surgical procedures, and rapid sequence induction. However, its usefulness is limited by the frequent occurrence of adverse effects like postoperative myalgia. Therefore this study aimed to assess the prevalence and associated factors of postoperative suxamethonium-induced myalgia. An institutional-based cross-sectional study was conducted on 210 patients who underwent surgery with general anesthesia. The data was collected by using structured and pretested questionnaires and analyzed using SPSS version 20.0. Logistic regression was conducted to identify significant predictors based on a P-value of less than 0.05 with a 95% confidence level. Among 210 patients the prevalence of suxamethonium-induced postoperative myalgia in the first 48 h was 88 (41.9%). Patients having previous anesthesia and surgical exposure (AOR 5.29, 95% CI 1.86-15.05), patients having a co-existing disease (AOR 2.69, 95% CI 1.08-6.67), patients that had not taken premedication (analgesia) (AOR 4.64, 95% CI 1.69-12.74), anesthesia maintenance using halothane (AOR 4.5 95% CI 1.7-11.4) and relaxation maintained with suxamethonium (AOR 3.1, 95% CI 1.2-8.1) were significantly associated with the prevalence of postoperative myalgia. The magnitude of suxamethonium-induced postoperative myalgia was high. So it is better to do with preventive techniques. As much as possible it is better to avoid using suxamethonium and necessary to use better to Premedicate with nonsteroidal anti-inflammatory drugs and non-depolarizing neuromuscular medications.
(© 2024. The Author(s).)
References: Anesthesiology. 2003 Jun;98(6):1312-4. (PMID: 12766637)
Br J Anaesth. 1968 Aug;40(8):602-6. (PMID: 5243759)
Anesth Essays Res. 2022 Jan-Mar;16(1):89-93. (PMID: 36249152)
Cureus. 2021 Nov 21;13(11):e19793. (PMID: 34820250)
J Muscle Res Cell Motil. 2010 Jul;31(1):13-33. (PMID: 20049631)
Anesthesiology. 2006 Dec;105(6):1087-97. (PMID: 17122571)
Br J Anaesth. 1993 Aug;71(2):238-41. (PMID: 8123399)
Patient Saf Surg. 2021 Apr 21;15(1):17. (PMID: 33882981)
J Postgrad Med. 2014 Jan-Mar;60(1):16-20. (PMID: 24625934)
Med Oral Patol Oral Cir Bucal. 2012 Nov 01;17(6):e1034-41. (PMID: 22549669)
J Clin Lipidol. 2017 Sep - Oct;11(5):1134-1144. (PMID: 28807461)
Pain. 2020 May;161(5):1044-1051. (PMID: 31917772)
Acta Anaesthesiol Scand. 2003 Feb;47(2):180-4. (PMID: 12631047)
J Anesth Hist. 2019 Jul;5(3):65-84. (PMID: 31570201)
Br J Oral Surg. 1983 Dec;21(4):290-7. (PMID: 6580915)
Rheumatol Rehabil. 1982 Feb;21(1):31-5. (PMID: 7058294)
J Orthop Sports Phys Ther. 2011 Sep;41(9):644-50. (PMID: 21885906)
J Postgrad Med. 2012 Jan-Mar;58(1):19-22. (PMID: 22387644)
Anesthesiology. 2005 Oct;103(4):877-84. (PMID: 16192781)
BMC Musculoskelet Disord. 2017 Jun 17;18(1):265. (PMID: 28623906)
Pain. 2009 Nov;146(1-2):65-74. (PMID: 19665301)
Proc Natl Acad Sci U S A. 2008 Jun 24;105(25):8784-9. (PMID: 18574153)
Crit Care Res Pract. 2021 Feb 25;2021:6613118. (PMID: 33708444)
Anaesthesia. 2000 Feb;55(2):144-52. (PMID: 10651675)
J Pain Res. 2016 Jul 06;9:503-8. (PMID: 27462175)
Anaesthesia. 2017 Jun;72(6):765-777. (PMID: 28654173)
J Anaesthesiol Clin Pharmacol. 2012 Jan;28(1):81-5. (PMID: 22345952)
World J Surg. 2017 Dec;41(12):3038-3045. (PMID: 29030677)
Pain. 2013 Sep;154(9):1807-1819. (PMID: 23742795)
Anesth Analg. 2006 Jan;102(1):151-5. (PMID: 16368821)
Acta Anaesthesiol Scand. 2012 Jan;56(1):3-16. (PMID: 22092267)
فهرسة مساهمة: Keywords: General anesthesia; Muscle pain; Myalgia; Surgery; Suxamethonium
المشرفين على المادة: J2R869A8YF (Succinylcholine)
تواريخ الأحداث: Date Created: 20240717 Date Completed: 20240717 Latest Revision: 20240802
رمز التحديث: 20240802
مُعرف محوري في PubMed: PMC11255331
DOI: 10.1038/s41598-024-65779-7
PMID: 39019942
قاعدة البيانات: MEDLINE
الوصف
تدمد:2045-2322
DOI:10.1038/s41598-024-65779-7