دورية أكاديمية
Disability, comorbidities and risk determinants at end of TB treatment in Kenya, Uganda, Zambia and Zimbabwe.
| العنوان: | Disability, comorbidities and risk determinants at end of TB treatment in Kenya, Uganda, Zambia and Zimbabwe. |
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| المؤلفون: | Adakun SA; Mulago National Referral Hospital, Kampala, Uganda., Banda FM; University Teaching Hospital, Ministry of Health, Lusaka, Zambia., Bloom A; Credence, Contractor for USAID Health Training, Advisory, and Support Contract (GHTASC), Washington DC, USA., Bochnowicz M; Credence, Contractor for USAID Health Training, Advisory, and Support Contract (GHTASC), Washington DC, USA., Chakaya J; Department of Medicine, Therapeutics, Dermatology and Psychiatry Kenyatta University, Nairobi.; Respiratory Society of Kenya, Nairobi, Kenya., Chansa A; Ndola Teaching Hospital, Ministry of Health, Ndola, Zambia., Chiguvare H; United States Agency for International Development (USAID), Harare, Zimbabwe., Chimzizi R; Ministry of Health, USAID Long-term Exceptional Technical Assistance Project, Genesis, Lusaka, Zambia., Colvin C; United States Agency for International Development (USAID), Harare, Zimbabwe., Dongo JP; International Union Against Tuberculosis and Lung Disease (The Union) Uganda Office, Kampala, Uganda., Durena A; United States Agency for International Development (USAID), Harare, Zimbabwe., Duri C; Directorate of Health Services, Harare City Council, Harare, Zimbabwe., Edmund R; United States Agency for International Development (USAID), Harare, Zimbabwe., Harries AD; The Union, Paris, France.; Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK., Kathure I; Ministry of Health, Division of National TB, Leprosy and Lung Disease Programme, Nairobi, Kenya., Kavenga FN; Ministry of Health and Child Care, AIDS and TB Department, Harare, Zimbabwe., Lin Y; The Union, Paris, France., Luzze H; National Tuberculosis and Leprosy Programme, Ministry of Health, Kampala, Uganda., Mbithi I; Respiratory Society of Kenya, Nairobi, Kenya., Mputu M; National Tuberculosis Programme, Ministry of Health/USAID TBLON, Lusaka; Zambia., Mubanga A; National Tuberculosis Programme, Ministry of Health/USAID TBLON, Lusaka; Zambia., Nair D; The Union, Paris, France., Ngwenya M; Ministry of Health and Child Care, AIDS and TB Department, Harare, Zimbabwe., Okotu B; Ministry of Health, Division of National TB, Leprosy and Lung Disease Programme, Nairobi, Kenya., Owiti P; USAID, Health, Population and Nutrition Office, Kenya and East Africa, Nairobi., Owuor A; Kenyatta National Hospital, Nairobi, Kenya., Thekkur P; The Union, Paris, France., Timire C; The Union, Paris, France.; Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK.; Ministry of Health and Child Care, AIDS and TB Department, Harare, Zimbabwe., Turyahabwe S; National Tuberculosis and Leprosy Programme, Ministry of Health, Kampala, Uganda., Tweyongyere E; National Tuberculosis and Leprosy Programme, Ministry of Health, Kampala, Uganda., YaDiul M; USAID, Washington DC, USA., Zachariah R; UNICEF/UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases (TDR), World Health Organization, Geneva, Switzerland., Zimba K; USAID, Lusaka, Zambia. |
| مؤلفون مشاركون: | Kenya, Uganda, Zambia, and Zimbabwe TB Disability Study Group (members listed here in alphabetical order): |
| المصدر: | IJTLD open [IJTLD Open] 2024 May 01; Vol. 1 (5), pp. 197-205. Date of Electronic Publication: 2024 May 01 (Print Publication: 2024). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: International Union against Tuberculosis and Lung Disease Country of Publication: France NLM ID: 9918803487706676 Publication Model: eCollection Cited Medium: Internet ISSN: 3005-7590 (Electronic) Linking ISSN: 30057590 NLM ISO Abbreviation: IJTLD Open Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: [Paris, France] : International Union against Tuberculosis and Lung Disease, [2024]- |
| مستخلص: | Background: We examined the feasibility of assessing and referring adults successfully completing TB treatment for comorbidities, risk determinants and disability in health facilities in Kenya, Uganda, Zambia and Zimbabwe. Methods: This was a cross-sectional study within national TB programmes. Results: Health workers assessed 1,063 patients (78% of eligible) in a median of 22 min [IQR 16-35] and found it useful and feasible to accomplish in addition to other responsibilities. For comorbidities, 476 (44%) had HIV co-infection, 172 (16%) had high blood pressure (newly detected in 124), 43 (4%) had mental health disorders (newly detected in 33) and 36 (3%) had diabetes mellitus. The most common risk determinants were 'probable alcohol dependence' (15%) and malnutrition (14%). Disability, defined as walking <400 m in 6 min, was found in 151/882 (17%). Overall, 763 (72%) patients had at least one comorbidity, risk determinant and/or disability. At least two-thirds of eligible patients were referred for care, although 80% of those with disability needed referral outside their original health facility. Conclusions: Seven in 10 patients completing TB treatment had at least one comorbidity, risk determinant and/or disability. This emphasises the need for offering early patient-centred care, including pulmonary rehabilitation, to improve quality of life, reduce TB recurrence and increase long-term survival. Competing Interests: Conflicts of interest: none declared. (© 2024 The Authors.) |
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| معلومات مُعتمدة: | 001 International WHO_ World Health Organization |
| فهرسة مساهمة: | Keywords: Real-time operational research; SORT IT; TB-associated disability; TB-associated lung disease; Universal health coverage Local Abstract: [Publisher, French] Nous avons examiné la faisabilité d'évaluer et de référer les adultes ayant terminé avec succès le traitement de la TB pour les comorbidités, les déterminants de risque et l'invalidité dans les établissements de santé au Kenya, en Ouganda, en Zambie et au Zimbabwe. [Publisher, French] Il s'agissait d'une étude transversale menée dans le cadre des programmes nationaux de lutte contre la TB. [Publisher, French] Les agents de santé ont évalué 1 063 patients (78% des personnes éligibles) en médiane de 22 min (IQR 16–35) et ont jugé utile et réalisable d'accomplir cette tâche en plus de leurs autres responsabilités. Pour les comorbidités, 476 (44%) étaient co-infectés par le VIH, 172 (16%) souffraient d'hypertension artérielle (dont 124 nouvellement diagnostiqués), 43 (4%) présentaient des troubles de santé mentale (dont 33 nouvellement diagnostiqués) et 36 (3%) étaient diabétiques. Les déterminants de risque les plus courants étaient une « dépendance probable à l'alcool » (15%) et la malnutrition (14%). L'invalidité, définie comme une marche <400 m en 6 min, a été observée chez 151/882 (17%) des patients. Dans l'ensemble, 763 (72%) des patients présentaient au moins une comorbidité, un déterminant de risque et/ou une invalidité. Au moins deux tiers des patients éligibles ont été référés pour des soins, bien que 80% de ceux souffrant d'invalidité aient besoin d'être référés en dehors de leur établissement de santé d'origine. [Publisher, French] Sept patients sur 10 ayant terminé le traitement de la TB présentaient au moins une comorbidité, un déterminant de risque et/ou une invalidité. Cela souligne la nécessité d'offrir des soins précoces centrés sur le patient, y compris une réadaptation pulmonaire, pour améliorer la qualité de vie, réduire la récurrence de la TB et augmenter la survie à long terme. |
| تواريخ الأحداث: | Date Created: 20240718 Latest Revision: 20240824 |
| رمز التحديث: | 20240826 |
| مُعرف محوري في PubMed: | PMC11249599 |
| DOI: | 10.5588/ijtldopen.24.0082 |
| PMID: | 39022778 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 3005-7590 |
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| DOI: | 10.5588/ijtldopen.24.0082 |