التفاصيل البيبلوغرافية
| العنوان: |
Update on Genetic Counselor Practice and Recommendations for Pediatric Cancer Predisposition Evaluation and Surveillance. |
| المؤلفون: |
Zelley K; Children's Hospital of Philadelphia, Philadelphia, PA, United States., Schienda J; Dana-Farber Cancer Institute, United States., Gallinger B; Hospital for Sick Children, Toronto, Ontario, Canada., Kohlmann WK; University of Utah, Salt Lake City, UT, United States., McGee RB; St. Jude Children's Research Hospital, Memphis, TN, United States., Scollon SR; Baylor College of Medicine, Houston, TX, United States., Schneider KW; University of Colorado Anschutz Medical Campus, Aurora, CO, United States. |
| المصدر: |
Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2024 Jul 22. Date of Electronic Publication: 2024 Jul 22. |
| Publication Model: |
Ahead of Print |
| نوع المنشور: |
Journal Article |
| اللغة: |
English |
| بيانات الدورية: |
Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE |
| أسماء مطبوعة: |
Original Publication: Denville, NJ : The Association, c1995- |
| مستخلص: |
In July 2023, the American Association for Cancer Research held the second Childhood Cancer Predisposition Workshop at which international experts in pediatric cancer predisposition met to update the previously published 2017 consensus statements on pediatric cancer predisposition syndromes. Since 2017, advances in tumor and germline genetic testing and increased understanding of cancer predisposition in pediatric cancer patients have led to significant changes in clinical care. Here, we provide an updated genetic counseling framework for pediatric oncology professionals. The framework includes: (1) referral indications and timing; (2) somatic and germline genetic testing options; (3) testing for adult-onset cancer predisposition syndromes in children with and without cancer; (4) evolving genetic counseling models to meet the increased demand for genetic testing; (5) barriers to cancer genetic testing and surveillance in children; and (6) psychosocial and equity considerations regarding cancer genetic testing and surveillance in children. Adaptable genetic counseling services are needed to provide support to pediatric oncology provider teams and diverse patients with pediatric cancer, cancer predisposition, and their families. |
| تواريخ الأحداث: |
Date Created: 20240722 Latest Revision: 20240722 |
| رمز التحديث: |
20240722 |
| DOI: |
10.1158/1078-0432.CCR-24-1165 |
| PMID: |
39037753 |
| قاعدة البيانات: |
MEDLINE |
