دورية أكاديمية
Integrative analysis of the ovarian metabolome and transcriptome of the Yaoshan chicken and its improved hybrids.
| العنوان: | Integrative analysis of the ovarian metabolome and transcriptome of the Yaoshan chicken and its improved hybrids. |
|---|---|
| المؤلفون: | Miao X; Institute of Animal Husbandry and Veterinary Medicine, Guizhou Academy of Agricultural Sciences, Guiyang, China.; College of Animal Science and Technology, China Agricultural University, Beijing, China., Wu T; College of Animal Science and Technology, Guangxi University, Nanning, China., Pan H; College of Animal Science and Technology, Guangxi University, Nanning, China., Zhang Y; College of Animal Science and Technology, China Agricultural University, Beijing, China., Liu J; Guizhou Province Livestock and Poultry Genetic Resources Management Station, Guiyang, China., Fan Y; Guizhou Province Livestock and Poultry Genetic Resources Management Station, Guiyang, China., Du L; Guizhou Province Livestock and Poultry Genetic Resources Management Station, Guiyang, China., Gong Y; Guizhou Province Livestock and Poultry Genetic Resources Management Station, Guiyang, China., Li L; Institute of Animal Husbandry and Veterinary Medicine, Guizhou Academy of Agricultural Sciences, Guiyang, China., Huang T; College of Animal Science and Technology, Guangxi University, Nanning, China., Ning Z; College of Animal Science and Technology, China Agricultural University, Beijing, China. |
| المصدر: | Frontiers in genetics [Front Genet] 2024 Jul 08; Vol. 15, pp. 1416283. Date of Electronic Publication: 2024 Jul 08 (Print Publication: 2024). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101560621 Publication Model: eCollection Cited Medium: Print ISSN: 1664-8021 (Print) Linking ISSN: 16648021 NLM ISO Abbreviation: Front Genet Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: Lausanne : Frontiers Research Foundation. |
| مستخلص: | Introduction: Laying performance is a key factor affecting production efficiency in poultry, but its molecular mechanism is still indistinct. In this study, Yaoshan chickens, a local breed in Guizhou, China, and merchant chickens (GYR) with higher egg yield after the three-line cross improvement hybridization of Yaoshan chickens were used as animal samples. Methods: To explore the regulatory mechanism of the diversities in laying performance, RNA-seq and ultra-performance liquid chromatographytandem mass spectrometry (UPLC-MS/MS) were used to describe the transcriptional and metabolic profiles of the ovaries of Yaoshan and GYR chickens. Results: At the transcriptional level, 288 differentially expressed genes were upregulated in Yaoshan chickens and 353 differentially expressed genes were upregulated in GYR chickens. In addition, GSEA showed that ECM-receptor interactions and the TGF-β signaling pathway were restrained, resulting in increased egg production in GYR chickens. Furthermore, the upregulation of thiamine and carnitine was identified by metabolomic analysis to facilitate the laying performance of hens. Finally, comprehensive analyses of the transcriptome and metabolome found that thiamine and carnitine were negatively correlated with ECM-receptor interactions and the TGF-β signaling pathway, which jointly regulate the laying performance of Yaoshan chickens and GYR chickens. Discussion: Taken together, our research delineates differences in the transcriptional and metabolic profiles of the ovaries of Yaoshan and GYR chickens during the peak egg production period and provides new hypotheses and clues for further research on poultry egg production performance and the improvement of economic benefits. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2024 Miao, Wu, Pan, Zhang, Liu, Fan, Du, Gong, Li, Huang and Ning.) |
| References: | Animal. 2018 Nov;12(11):2318-2326. (PMID: 29458450) Animals (Basel). 2022 Aug 09;12(16):. (PMID: 36009602) Nat Biotechnol. 2019 Aug;37(8):907-915. (PMID: 31375807) Biomed Res Int. 2020 Oct 06;2020:6909672. (PMID: 33083477) Poult Sci. 2021 Apr;100(4):101031. (PMID: 33684648) Mol Cell Endocrinol. 2022 Jul 15;552:111675. (PMID: 35577112) Br Poult Sci. 2021 Apr;62(2):304-309. (PMID: 33336589) Biol Reprod. 2011 Sep;85(3):548-55. (PMID: 21613630) Poult Sci. 2022 Jan;101(1):101524. (PMID: 34784514) Mol Reprod Dev. 2022 Sep;89(9):399-412. (PMID: 35802551) Anim Reprod Sci. 2019 Sep;208:106114. (PMID: 31405454) J Assist Reprod Genet. 2020 Mar;37(3):657-667. (PMID: 31974739) Front Immunol. 2021 Dec 22;12:800188. (PMID: 35003125) Cancer Genomics Proteomics. 2016 11-12;13(6):425-435. (PMID: 27807065) J Reprod Dev. 2015;61(5):391-7. (PMID: 26063610) J Ovarian Res. 2018 Jan 10;11(1):6. (PMID: 29321035) Front Genet. 2021 Mar 18;12:619196. (PMID: 33815464) Animals (Basel). 2022 Aug 31;12(17):. (PMID: 36077979) PeerJ. 2019 Oct 21;7:e7900. (PMID: 31656701) PLoS One. 2017 Mar 14;12(3):e0173824. (PMID: 28291821) Curr Drug Metab. 2011 Sep;12(7):667-78. (PMID: 21561431) Animals (Basel). 2021 Jan 15;11(1):. (PMID: 33467586) Bioinformatics. 2018 Sep 1;34(17):i884-i890. (PMID: 30423086) Anim Biotechnol. 2020 Aug;31(4):295-305. (PMID: 30961447) Reprod Fertil Dev. 2022 May;34(9):689-697. (PMID: 35366957) Theriogenology. 2011 Sep 15;76(5):785-93. (PMID: 21705056) Front Genet. 2021 May 19;12:671729. (PMID: 34093665) Mol Cell Endocrinol. 2015 Sep 5;412:104-15. (PMID: 26054746) G3 (Bethesda). 2018 Feb 2;8(2):469-476. (PMID: 29187421) JPEN J Parenter Enteral Nutr. 2015 Jul;39(5):503-20. (PMID: 25564426) Proc Natl Acad Sci U S A. 2017 Jun 13;114(24):E4753-E4761. (PMID: 28559354) J Food Sci. 2020 Apr;85(4):1319-1327. (PMID: 32175699) Poult Sci. 2020 Feb;99(2):1199-1208. (PMID: 32036969) Br Poult Sci. 2020 Oct;61(5):538-549. (PMID: 32306752) Cell Tissue Res. 2006 Jul;325(1):143-9. (PMID: 16525833) Arch Pharm Res. 2013 Sep;36(9):1133-9. (PMID: 23760618) Animals (Basel). 2022 Sep 02;12(17):. (PMID: 36077995) Mol Biosyst. 2014 Nov;10(11):2984-93. (PMID: 25178933) Vet World. 2020 Mar;13(3):407-412. (PMID: 32367942) J Reprod Dev. 2020 Feb 14;66(1):1-7. (PMID: 31787727) BMC Genet. 2019 Aug 14;20(1):67. (PMID: 31412760) J Chromatogr A. 2014 Aug 1;1353:99-105. (PMID: 24811151) Poult Sci. 2019 Nov 1;98(11):6063-6070. (PMID: 31149725) Br J Nutr. 1997 Oct;78(4):615-23. (PMID: 9389887) Anim Genet. 2016 Feb;47(1):68-80. (PMID: 26592359) |
| فهرسة مساهمة: | Keywords: chicken; egg production; metabolomics; ovary; transcriptome |
| تواريخ الأحداث: | Date Created: 20240723 Latest Revision: 20240724 |
| رمز التحديث: | 20240725 |
| مُعرف محوري في PubMed: | PMC11260793 |
| DOI: | 10.3389/fgene.2024.1416283 |
| PMID: | 39040995 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1664-8021 |
|---|---|
| DOI: | 10.3389/fgene.2024.1416283 |