دورية أكاديمية
High Intraocular Pressure Is Independently Associated With New-Onset Systemic Hypertension Over a 10-Year Period.
| العنوان: | High Intraocular Pressure Is Independently Associated With New-Onset Systemic Hypertension Over a 10-Year Period. |
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| المؤلفون: | Umetsu A; Department of Ophthalmology, School of Medicine, Sapporo Medical University., Tanaka M; Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine.; Tanaka Medical Clinic., Sato T; Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine.; Department of Cellular Physiology and Signal Transduction, Sapporo Medical University School of Medicine., Akiyama Y; Department of Neurosurgery, Sapporo Medical University School of Medicine., Endo K; Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine., Mori K; Department of Immunology and Microbiology, National Defense Medical College., Ohnishi H; Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine.; Department of Public Health, Sapporo Medical University School of Medicine., Watanabe M; Department of Ophthalmology, School of Medicine, Sapporo Medical University., Ohguro H; Department of Ophthalmology, School of Medicine, Sapporo Medical University., Hanawa N; Department of Health Checkup and Promotion, Keijinkai Maruyama Clinic., Furuhashi M; Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine. |
| المصدر: | Circulation journal : official journal of the Japanese Circulation Society [Circ J] 2024 Sep 25; Vol. 88 (10), pp. 1689-1696. Date of Electronic Publication: 2024 Jul 24. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Japanese Circulation Society Country of Publication: Japan NLM ID: 101137683 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1347-4820 (Electronic) Linking ISSN: 13469843 NLM ISO Abbreviation: Circ J Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Kyoto, Japan : Japanese Circulation Society, [2002- |
| مواضيع طبية MeSH: | Hypertension*/epidemiology , Hypertension*/physiopathology , Intraocular Pressure*, Humans ; Male ; Female ; Middle Aged ; Risk Factors ; Adult ; Follow-Up Studies ; Japan/epidemiology ; Antihypertensive Agents/therapeutic use ; Blood Pressure |
| مستخلص: | Background: Systemic hypertension (HT) is associated with the development of increased intraocular pressure (IOP), a risk factor for glaucoma. However, it remains unclear whether high IOP is a risk factor for HT.Methods and Results: We investigated 7,487 Japanese individuals (4,714 men, 2,773 women; mean [±SD] age 49±9 years) who underwent annual health checkups in 2006. Over the 10-year follow-up period, 1,232 (24.3%) men and 370 (11.5%) women developed new-onset HT, defined as initiation of antihypertensive drug treatment or blood pressure ≥140/90 mmHg. After dividing IOP into tertiles (T1-T3), Cox proportional hazards analysis (adjusted for age, sex, systolic blood pressure, obesity, current smoking, alcohol consumption, family history of HT, estimated glomerular filtration rate, and diabetes and dyslipidemia diagnoses at baseline) revealed a significantly higher risk of newly developed HT in T3 (IOP ≥14 mmHg; hazard ratio 1.14; 95% confidence interval 1.01-1.29; P=0.038) using T1 (IOP ≤11 mmHg) as the reference group. There was no significant interaction between sex and IOP tertile (P=0.153). A restricted cubic spline model showed a gradual but robust increase in the hazard ratio for new-onset HT with increasing IOP. Conclusions: High IOP is an independent risk factor for the development of HT over a 10-year period. |
| فهرسة مساهمة: | Keywords: Hypertension; Intraocular pressure; Risk factor |
| المشرفين على المادة: | 0 (Antihypertensive Agents) |
| تواريخ الأحداث: | Date Created: 20240724 Date Completed: 20240925 Latest Revision: 20240925 |
| رمز التحديث: | 20240926 |
| DOI: | 10.1253/circj.CJ-24-0241 |
| PMID: | 39048347 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1347-4820 |
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| DOI: | 10.1253/circj.CJ-24-0241 |