دورية أكاديمية
أعرض في EDS

Burden of early neonatal mortality in Sub-Saharan Africa. A systematic review and meta-analysis.

التفاصيل البيبلوغرافية
العنوان: Burden of early neonatal mortality in Sub-Saharan Africa. A systematic review and meta-analysis.
المؤلفون: Moges N; Department of Pediatrics and Child Health Nursing, College of Health sciences, Debre Tabor University, Debre Tabor, Ethiopia., Dessie AM; Department of Public Health, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia., Anley DT; Department of Public Health, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia., Zemene MA; Department of Public Health, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia., Gebeyehu NA; Department of Midwifery, College of Medicine and Health Science, Wolaita Sodo University, Wolaita Sodo, Ethiopia., Adella GA; Department of Reproductive Health and Nutrition, School of Public Health, Woliata Sodo University, Woliata Sodo, Ethiopia., Kassie GA; Department of Epidemiology and Biostatistics, School of Public Health, Woliata Sodo University, Woliata Sodo, Ethiopia., Mengstie MA; Department of Biochemistry, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia., Seid MA; Unit of Physiology, Department of Biomedical Science, College of Health Science, Debre Tabor University, Debre Tabor, Ethiopia., Abebe EC; Department of Biochemistry, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia., Gesese MM; Department of Midwifery, College of Medicine and Health Science, Wolaita Sodo University, Wolaita Sodo, Ethiopia., Kebede YS; Department of Medical Laboratory Science, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia., Feleke SF; Department of Public Health, College of Health Sciences, Woldia University, Woldia, Ethiopia., Dejenie TA; Department of Medical Biochemistry, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia., Tesfa NA; School of Medicine, College of Health Science, Woldia University, Woldia, Ethiopia., Bayih WA; Department of Pediatrics and Child Health Nursing, College of Health sciences, Debre Tabor University, Debre Tabor, Ethiopia.; Department of Epidemiology and preventive Medicine, School of Public Health and Preventive Medicine, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Victoria, Australia., Chanie ES; Department of Pediatrics and Child Health Nursing, College of Health sciences, Debre Tabor University, Debre Tabor, Ethiopia., Bantie B; Department of Comprehensive Nursing, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.
المصدر: PloS one [PLoS One] 2024 Jul 25; Vol. 19 (7), pp. e0306297. Date of Electronic Publication: 2024 Jul 25 (Print Publication: 2024).
نوع المنشور: Journal Article; Systematic Review; Meta-Analysis
اللغة: English
بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
أسماء مطبوعة: Original Publication: San Francisco, CA : Public Library of Science
مواضيع طبية MeSH: Infant Mortality*/trends, Humans ; Africa South of the Sahara/epidemiology ; Infant, Newborn ; Infant ; Female
مستخلص: Background: Globally, with a neonatal mortality rate of 27/1000 live births, Sub-Saharan Africa has the highest rate in the world and is responsible for 43% of all infant fatalities. In the first week of life, almost three-fourths of neonatal deaths occur and about one million babies died on their first day of life. Previous studies lack conclusive evidence regarding the overall estimate of early neonatal mortality in Sub-Saharan Africa. Therefore, this review aimed to pool findings reported in the literature on magnitude of early neonatal mortality in Sub-Saharan Africa.
Methods: This review's output is the aggregate of magnitude of early neonatal mortality in sub-Saharan Africa. Up until June 8, 2023, we performed a comprehensive search of the databases PubMed/Medline, PubMed Central, Hinary, Google, Cochrane Library, African Journals Online, Web of Science, and Google Scholar. The studies were evaluated using the JBI appraisal check list. STATA 17 was employed for the analysis. Measures of study heterogeneity and publication bias were conducted using the I2 test and the Eggers and Beggs tests, respectively. The Der Simonian and Laird random-effect model was used to calculate the combined magnitude of early neonatal mortality. Besides, subgroup analysis, sensitivity analysis, and meta regression were carried out to identify the source of heterogeneity.
Results: Fourteen studies were included from a total of 311 articles identified by the search with a total of 278,173 participants. The pooled magnitude of early neonatal mortality in sub-Saharan Africa was 80.3 (95% CI 66 to 94.6) per 1000 livebirths. Ethiopia had the highest pooled estimate of early neonatal mortality rate, at 20.1%, and Cameroon had the lowest rate, at 0.5%. Among the included studies, both the Cochrane Q test statistic (χ2 = 6432.46, P <0.001) and I2 test statistic (I2 = 99.80%, p <0.001) revealed statistically significant heterogeneity. Egger's weighted regression (p <0.001) and funnel plot show evidence of publication bias in this meta-analysis.
Conclusion: This review demonstrated that the pooled magnitude of early neonatal mortality in sub-Saharan Africa is substantial. Therefore, governmental and nongovernmental agencies, international organizations, healthcare providers and institutions and academic and research institutions should give a due attention and design strategies to reduce early neonatal mortality in Sub-Saharan Africa.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright: © 2024 Moges et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
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تواريخ الأحداث: Date Created: 20240725 Date Completed: 20240725 Latest Revision: 20240728
رمز التحديث: 20240728
مُعرف محوري في PubMed: PMC11271883
DOI: 10.1371/journal.pone.0306297
PMID: 39052580
قاعدة البيانات: MEDLINE
الوصف
تدمد:1932-6203
DOI:10.1371/journal.pone.0306297