Assessment of the effect of experimental gel of pregabalin associated with 35% hydrogen peroxide bleaching on bovine dental enamel: an in vitro study.

التفاصيل البيبلوغرافية
العنوان:	Assessment of the effect of experimental gel of pregabalin associated with 35% hydrogen peroxide bleaching on bovine dental enamel: an in vitro study.
المؤلفون:	Xavier GMB; Department of Restorative Dentistry, Faculty of Dentistry, Federal University of Pará, Av. Augusto Corrêa, nº 01, Belém, PA, 66.075-110, Brazil., Gil GS; Department of Restorative Dentistry, Faculty of Dentistry, Federal University of Pará, Av. Augusto Corrêa, nº 01, Belém, PA, 66.075-110, Brazil., Paes YFO; Department of Restorative Dentistry, Faculty of Dentistry, Federal University of Pará, Av. Augusto Corrêa, nº 01, Belém, PA, 66.075-110, Brazil., de Meneses Costa Ferreira LM; Pharmaceutical Nanotechnology Laboratory, Faculty of Pharmacy, Federal University of Pará, Av. Augusto Corrêa, nº 01, Belém, PA, 66.075-110, Brazil., Silva CM; Department of Restorative Dentistry, Faculty of Dentistry, Federal University of Pará, Av. Augusto Corrêa, nº 01, Belém, PA, 66.075-110, Brazil., Ribeiro-Costa RM; Pharmaceutical Nanotechnology Laboratory, Faculty of Pharmacy, Federal University of Pará, Av. Augusto Corrêa, nº 01, Belém, PA, 66.075-110, Brazil., Araújo JLN; Department of Restorative Dentistry, Faculty of Dentistry, Federal University of Pará, Av. Augusto Corrêa, nº 01, Belém, PA, 66.075-110, Brazil. jesuinalamartine@hotmail.com.
المصدر:	Odontology [Odontology] 2024 Jul 26. Date of Electronic Publication: 2024 Jul 26.
Publication Model:	Ahead of Print
نوع المنشور:	Journal Article
اللغة:	English
بيانات الدورية:	Publisher: Springer-Verlag Tokyo Country of Publication: Japan NLM ID: 101134822 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-1255 (Electronic) Linking ISSN: 16181247 NLM ISO Abbreviation: Odontology Subsets: MEDLINE
أسماء مطبوعة:	Original Publication: Tokyo : Springer-Verlag Tokyo, c2001-
مستخلص:	To assess the effect of bleaching with gel of pregabalin associated with 35% hydrogen peroxide on the mechanical and chemical properties and ultramorphology of dental enamel. Thirty-six (36) specimens of bovine dental incisors were obtained and divided into three groups (n = 12), namely: CG = bleaching with 35% hydrogen peroxide; KFG = bleaching with 5% potassium nitrate and 2% sodium fluoride gel + 35% hydrogen peroxide; and PGG = bleaching with experimental gel of pregabalin + 35% hydrogen peroxide. The specimens were assessed with respect to Knoop microhardness, surface roughness, and colour change, before and after bleaching. They were also assessed using scanning electron microscopy and energy-dispersive spectroscopy after treatments. All groups exhibited an increase in surface roughness and a reduction in Knoop microhardness after the protocols. There was colour change in all groups, with no difference between them. In addition, there were changes in enamel morphology and non-significant loss of calcium and phosphorus. The experimental gel of pregabalin did not influence the action of 35% hydrogen peroxide, yielding results similar to those of the other groups assessed in all the parameters. Therefore, the gel of pregabalin can be an alternative for topical application on the surfaces of the teeth in association with bleaching treatments. (© 2024. The Author(s), under exclusive licence to The Society of The Nippon Dental University.)
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فهرسة مساهمة:	Keywords: Dental bleaching; Enamel; Experimental gel; Hydrogen peroxide; Pregalin
تواريخ الأحداث:	Date Created: 20240726 Latest Revision: 20240726
رمز التحديث:	20240727
DOI:	10.1007/s10266-024-00978-2
PMID:	39060896
قاعدة البيانات:	MEDLINE

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تدمد:	1618-1255
DOI:	10.1007/s10266-024-00978-2