دورية أكاديمية
Clinical impact of MRI on indeterminate findings on contrast-enhanced CT suspicious of HCC.
| العنوان: | Clinical impact of MRI on indeterminate findings on contrast-enhanced CT suspicious of HCC. |
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| المؤلفون: | Kristiansen MK; Department of Hepatology & Gastroenterology, Aarhus University Hospital, Aarhus N, Denmark., Larsen LP; Department of Radiology, Aarhus University Hospital, Aarhus N, Denmark., Villadsen GE; Department of Hepatology & Gastroenterology, Aarhus University Hospital, Aarhus N, Denmark., Sørensen M; Department of Hepatology & Gastroenterology, Aarhus University Hospital, Aarhus N, Denmark.; Department of Internal Medicine, Viborg Regional Hospital, Viborg, Denmark. |
| المصدر: | Scandinavian journal of gastroenterology [Scand J Gastroenterol] 2024 Sep; Vol. 59 (9), pp. 1075-1080. Date of Electronic Publication: 2024 Jul 26. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Informa Healthcare Country of Publication: England NLM ID: 0060105 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1502-7708 (Electronic) Linking ISSN: 00365521 NLM ISO Abbreviation: Scand J Gastroenterol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: London : Informa Healthcare Original Publication: Oslo : Universitetsforlager |
| مواضيع طبية MeSH: | Carcinoma, Hepatocellular*/diagnostic imaging , Carcinoma, Hepatocellular*/pathology , Liver Neoplasms*/diagnostic imaging , Liver Neoplasms*/pathology , Magnetic Resonance Imaging* , Tomography, X-Ray Computed* , Contrast Media*, Humans ; Retrospective Studies ; Male ; Female ; Aged ; Middle Aged ; Liver Cirrhosis/diagnostic imaging ; Neoplasm Recurrence, Local/diagnostic imaging ; Aged, 80 and over ; Liver/diagnostic imaging ; Liver/pathology ; Adult |
| مستخلص: | Objectives: In patients evaluated for hepatocellular carcinoma (HCC), magnetic resonance imaging (MRI) is often used secondarily when multiphase contrast-enhanced computed tomography (ceCT) is inconclusive. We investigated the clinical impact of adding MRI. Materials and Methods: This single-institution retrospective study included 48 MRI scans (44 patients) conducted from May 2016 to July 2023 due to suspicion of HCC on a multiphase ceCT scan. Data included medical history, preceding and subsequent imaging, histology when available, and decisions made at multidisciplinary team meetings. Results: In case of possible HCC recurrence, 63% of the MRI scans were diagnostic of HCC. For 80% of the negative MRI scans, the patients were diagnosed with HCC within a median of 165 days in the suspicious area of the liver. In case of possible de-novo HCC in patients with cirrhosis, 22% of the scans were diagnostic of HCC and 33% of the negative MRI scans were of patients diagnosed with HCC within a median of 109 days. None of the non-cirrhotic patients with possible de-novo HCC and negative MRI scans (64%) were later diagnosed with HCC, but 3/5 of the indeterminate scans were of patients diagnosed with HCC in a biopsy. Conclusions: Secondary MRI to a multiphase ceCT scan suspicious of HCC is highly valuable in ruling out HCC in non-cirrhotic patients and in diagnosing HCC non-invasively in cirrhotic patients and patients with prior HCC. Patients with cirrhosis or prior HCC are still at high risk of having HCC if MRI results are inconclusive or negative. |
| فهرسة مساهمة: | Keywords: Hepatocellular carcinoma; diagnostic accuracy; diagnostic algorithm; liver biopsy; liver imaging; surveillance |
| المشرفين على المادة: | 0 (Contrast Media) |
| تواريخ الأحداث: | Date Created: 20240727 Date Completed: 20240829 Latest Revision: 20240829 |
| رمز التحديث: | 20240830 |
| DOI: | 10.1080/00365521.2024.2384952 |
| PMID: | 39061129 |
| قاعدة البيانات: | MEDLINE |
PDF full text from Publisher | تدمد: | 1502-7708 |
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| DOI: | 10.1080/00365521.2024.2384952 |