دورية أكاديمية
Ruthenium(II) Complex-Based Tetradentate Schiff Bases: Synthesis, Spectroscopic, Antioxidant, and Antibacterial Investigations.
| العنوان: | Ruthenium(II) Complex-Based Tetradentate Schiff Bases: Synthesis, Spectroscopic, Antioxidant, and Antibacterial Investigations. |
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| المؤلفون: | Es-Sounni B; Laboratory of Innovative Materials and Biotechnology of Naturel Resources, Faculty of Sciences, Moulay Ismail University, Meknes 50000, Morocco., Harboul K; Laboratory of Natural Resources and Environment, Polydisciplinary Faculty of Taza, Sidi Mohamed Ben Abdellah University of Fez, Taza 30050, Morocco., Mouhib A; Bioorganic Chemistry Team, Department of Chemistry, Faculty of Sciences, Chouaïb Doukkali University, El Jadida 24000, Morocco., Alanazi AS; Department of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah Bint Abdulrahman University, Riyadh 1167, Saudi Arabia., Hefnawy M; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia., Bakhouch M; Bioorganic Chemistry Team, Department of Chemistry, Faculty of Sciences, Chouaïb Doukkali University, El Jadida 24000, Morocco., Benali T; Laboratory of Natural Resources and Environment, Polydisciplinary Faculty of Taza, Sidi Mohamed Ben Abdellah University of Fez, Taza 30050, Morocco.; Environment and Health Team, Polydisciplinary Faculty of Safi, Cadi Ayyad University, Safi 46000, Morocco., Hammani K; Laboratory of Natural Resources and Environment, Polydisciplinary Faculty of Taza, Sidi Mohamed Ben Abdellah University of Fez, Taza 30050, Morocco., Mazoir N; Bioorganic Chemistry Team, Department of Chemistry, Faculty of Sciences, Chouaïb Doukkali University, El Jadida 24000, Morocco., El Yazidi M; Engineering Laboratory of Organometallic and Molecular Materials and Environment, Faculty of Sciences Dhar El Mahraz, University Sidi Mohamed Ben Abdellah, Fez 30000, Morocco., Benharref A; Laboratory of Natural Substances Chemistry, Faculty of Sciences Semlalia, Cadi Ayyad University, Marrakech 40000, Morocco., Fahim M; Laboratory of Innovative Materials and Biotechnology of Naturel Resources, Faculty of Sciences, Moulay Ismail University, Meknes 50000, Morocco. |
| المصدر: | International journal of molecular sciences [Int J Mol Sci] 2024 Jul 18; Vol. 25 (14). Date of Electronic Publication: 2024 Jul 18. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Basel, Switzerland : MDPI, [2000- |
| مواضيع طبية MeSH: | Schiff Bases*/chemistry , Schiff Bases*/pharmacology , Anti-Bacterial Agents*/pharmacology , Anti-Bacterial Agents*/chemistry , Anti-Bacterial Agents*/chemical synthesis , Antioxidants*/pharmacology , Antioxidants*/chemistry , Antioxidants*/chemical synthesis , Ruthenium*/chemistry , Coordination Complexes*/pharmacology , Coordination Complexes*/chemistry , Coordination Complexes*/chemical synthesis , Microbial Sensitivity Tests*, Bacillus subtilis/drug effects |
| مستخلص: | In this work, we describe the synthesis of novel Ruthenium (II) complex-based salen Schiff bases. The obtained Ruthenium (II) complexes are characterized using usual spectroscopic and spectrometric techniques, viz., IR, UV-Vis, NMR ( 1 H and 13 C), powder X-ray diffraction, and HRMS. Further techniques, such as DTA-TGA and elemental analysis, are used to well establish the structure of the obtained complexes. Octahedral geometries are tentatively proposed for the new Ru(II) complexes. The measured molar conductance for the Ruthenium (II) complexes shows their electrolytic nature (4.24-4.44 S/m). The new Ru(II) complexes are evaluated for their antioxidant and antibacterial activities. The DPPH radical scavenging, FRAP, and total antioxidant capacity (TAC) assays show that the obtained complexes are more potent than the used positive control. They also exhibit promising antibacterial responses against pathogen bacteria: [RuH |
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| معلومات مُعتمدة: | PNURSP2024R342 Princess Nourah Bint Abdulrahman University researcher supporting; RSPD2024R754 King Saud University |
| فهرسة مساهمة: | Keywords: Ru(II) complexes; antibacterial; antioxidant; salen Schiff bases; spectroscopy |
| المشرفين على المادة: | 0 (Schiff Bases) 0 (Anti-Bacterial Agents) 0 (Antioxidants) 7UI0TKC3U5 (Ruthenium) 0 (Coordination Complexes) |
| تواريخ الأحداث: | Date Created: 20240727 Date Completed: 20240727 Latest Revision: 20240729 |
| رمز التحديث: | 20240729 |
| مُعرف محوري في PubMed: | PMC11277530 |
| DOI: | 10.3390/ijms25147879 |
| PMID: | 39063120 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1422-0067 |
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| DOI: | 10.3390/ijms25147879 |