دورية أكاديمية
Protocol for continuous intravenous drug delivery with implantable iPrecio pump in free-moving rats and mice.
| العنوان: | Protocol for continuous intravenous drug delivery with implantable iPrecio pump in free-moving rats and mice. |
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| المؤلفون: | Giri T; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address: tusargiri@wustl.edu., Palanisamy A; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address: arvind.palanisamy@wustl.edu. |
| المصدر: | STAR protocols [STAR Protoc] 2024 Sep 20; Vol. 5 (3), pp. 103224. Date of Electronic Publication: 2024 Jul 27. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Cell Press Country of Publication: United States NLM ID: 101769501 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-1667 (Electronic) Linking ISSN: 26661667 NLM ISO Abbreviation: STAR Protoc Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: [Cambridge, MA] : Cell Press, [2020]- |
| مواضيع طبية MeSH: | Infusion Pumps, Implantable* , Oxytocin*/administration & dosage, Animals ; Rats ; Mice ; Female ; Pregnancy ; Drug Delivery Systems/methods ; Drug Delivery Systems/instrumentation ; Infusions, Intravenous ; Administration, Intravenous |
| مستخلص: | Variable-rate delivery of intravenous drugs is difficult to achieve with a tethered infusion system in a freely moving animal. Here, we present a protocol for continuous intravenous delivery of oxytocin in pregnant rats and mice. We describe steps for using an implantable, preprogrammed, microprocessor-controlled infusion pump connected to the jugular vein to induce labor. This protocol can be adapted to a variety of experimental paradigms in non-pregnant animals where precise intravenous pharmacological manipulation is desired. For complete details on the use and execution of this protocol, please refer to Giri et al. 1 , 2 . Competing Interests: Declaration of interests The authors declare no competing interests. (Copyright © 2024 The Author(s). Published by Elsevier Inc. All rights reserved.) |
| معلومات مُعتمدة: | P30 DK056341 United States DK NIDDK NIH HHS |
| فهرسة مساهمة: | Keywords: Health Sciences; Model Organisms; Neuroscience |
| المشرفين على المادة: | 50-56-6 (Oxytocin) |
| تواريخ الأحداث: | Date Created: 20240728 Date Completed: 20240926 Latest Revision: 20240926 |
| رمز التحديث: | 20240926 |
| مُعرف محوري في PubMed: | PMC11338190 |
| DOI: | 10.1016/j.xpro.2024.103224 |
| PMID: | 39068650 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2666-1667 |
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| DOI: | 10.1016/j.xpro.2024.103224 |