دورية أكاديمية
أعرض في EDS

The erythrocyte sedimentation rate and other markers of inflammation in cats tested for Leishmania infantum and feline immunodeficiency virus antibodies.

التفاصيل البيبلوغرافية
العنوان: The erythrocyte sedimentation rate and other markers of inflammation in cats tested for Leishmania infantum and feline immunodeficiency virus antibodies.
المؤلفون: Donato G; Università di Messina, Messina, Italy.; ASC 'I Periodeuti', Reggio Calabria, Italy., Caspanello T; Università di Messina, Messina, Italy.; ASC 'I Periodeuti', Reggio Calabria, Italy., Caprì A; ASC 'I Periodeuti', Reggio Calabria, Italy.; Clinica Veterinaria Camagna-VetPartners, Reggio Calabria, Italy., De Majo M; Università di Messina, Messina, Italy.; ASC 'I Periodeuti', Reggio Calabria, Italy., Iannelli NM; Università di Messina, Messina, Italy.; ASC 'I Periodeuti', Reggio Calabria, Italy.; Clinica Veterinaria Camagna-VetPartners, Reggio Calabria, Italy., Rosace F; Università di Messina, Messina, Italy.; ASC 'I Periodeuti', Reggio Calabria, Italy.; Clinica Veterinaria Camagna-VetPartners, Reggio Calabria, Italy., Bruno F; National Reference Center for Leishmaniasis (C.Re.Na.L.), Istituto Zooprofilattico Sperimentale della Sicilia, Palermo, Italy., Castelli G; National Reference Center for Leishmaniasis (C.Re.Na.L.), Istituto Zooprofilattico Sperimentale della Sicilia, Palermo, Italy., Pennisi MG; ASC 'I Periodeuti', Reggio Calabria, Italy. mariagrazia.pennisi@unime.it., Masucci M; Università di Messina, Messina, Italy.; ASC 'I Periodeuti', Reggio Calabria, Italy.
المصدر: Parasites & vectors [Parasit Vectors] 2024 Jul 30; Vol. 17 (1), pp. 324. Date of Electronic Publication: 2024 Jul 30.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101462774 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-3305 (Electronic) Linking ISSN: 17563305 NLM ISO Abbreviation: Parasit Vectors Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : BioMed Central
مواضيع طبية MeSH: Leishmania infantum*/immunology , Immunodeficiency Virus, Feline*/immunology , Cat Diseases*/blood , Cat Diseases*/parasitology , Cat Diseases*/immunology , Inflammation*/veterinary , Inflammation*/blood , Biomarkers*/blood , Leishmaniasis, Visceral*/veterinary , Leishmaniasis, Visceral*/blood , Leishmaniasis, Visceral*/immunology , Leishmaniasis, Visceral*/parasitology , Blood Sedimentation*, Cats ; Animals ; Male ; Prospective Studies ; Antibodies, Viral/blood ; Female ; Feline Acquired Immunodeficiency Syndrome/blood ; Feline Acquired Immunodeficiency Syndrome/immunology ; Coinfection/veterinary ; Coinfection/parasitology ; Coinfection/virology ; Antibodies, Protozoan/blood
مستخلص: Background: In endemic areas, Leishmania infantum and feline immunodeficiency virus (FIV) co-infection occurs in cats, and may favour a progressive course of feline leishmaniosis. Abnormalities in serum protein fractions have been reported, but inflammation markers have scarcely been studied. Erythrocyte sediment rate (ESR) is a marker of inflammation that is poorly used in veterinary medicine, but it has been evaluated in EDTA blood using a recently introduced automatic device. We studied ESR and a pool of feline markers of inflammation (MoI) in cats L. infantum (Li + ) and/or FIV antibody-positive (Li + FIV + /FIV + ) with the aims (a) to evaluate ESR as MoI in cats with the infectious and clinical conditions considered and (b) to provide data about a pool of MoI never investigated in the feline infections studied and in other cat diseases before.
Methods: This prospective controlled study included 35 study group cats (Li + , n = 20; FIV +, n = 8; Li + FIV + , n = 7) and ten healthy antibody-negative control cats. Clinical findings at physical examination and selected clinical pathological abnormalities related to inflammation were statistically analysed in relation to the infectious status and ESR values.
Results: ESR values were higher in Li + , FIV + , and Li + FIV + cats compared with control cats, and 40% of the study group cats had ESR values above the reference interval (RI). ESR positively correlated with some positive MoI and negatively with some negative MoI studied. Additionally, a higher prevalence of ESR values above the RI has been detected in cats with hypoalbuminemia or hypergammaglobulinemia and higher ESR values were measured in cats with serum protein electrophoresis (SPE) fraction abnormalities. Correlations were also found with erythrocytes, hemoglobin, hematocrit and some erythrocyte indices. FIV + and Li + FIV + cats had a higher prevalence of increased ESR values, and almost all had SPE abnormalities and more severe clinical presentations compared with Li + cats.
Conclusions: Abnormal levels of MoI were found in almost all parameters studied, particularly in FIV + and Li + FIV + cats. Also, ESR can be used as a marker of inflammation in cats with L. infantum and/or FIV infection.
(© 2024. The Author(s).)
References: Animals (Basel). 2023 Aug 10;13(16):. (PMID: 37627371)
Parasit Vectors. 2021 Oct 10;14(1):525. (PMID: 34629081)
Am J Vet Res. 2003 Aug;64(8):1021-6. (PMID: 12926596)
Vet Parasitol. 2018 Aug 30;260:63-68. (PMID: 30197018)
Viruses. 2021 Jul 25;13(8):. (PMID: 34452315)
Vet World. 2021 Sep;14(9):2325-2331. (PMID: 34840450)
Vet Comp Oncol. 2020 Mar;18(1):105-116. (PMID: 31441996)
Parasit Vectors. 2016 Jun 03;9(1):317. (PMID: 27260142)
Viruses. 2023 Aug 21;15(8):. (PMID: 37632117)
Animals (Basel). 2023 Nov 28;13(23):. (PMID: 38067025)
Vet Sci. 2022 Sep 07;9(9):. (PMID: 36136697)
MethodsX. 2022 Nov 24;9:101934. (PMID: 36479590)
Vet Parasitol. 2018 Feb 15;251:131-137. (PMID: 29426470)
Health Sci Rep. 2024 Jan 25;7(1):e1843. (PMID: 38274138)
Vet Clin Pathol. 2010 Dec;39(4):464-73. (PMID: 21039711)
Parasit Vectors. 2023 May 12;16(1):161. (PMID: 37173777)
Parasit Vectors. 2018 Mar 20;11(1):136. (PMID: 29554931)
Vet Clin Pathol. 2012 Dec;41(4):441-53. (PMID: 23240820)
ISRN Parasitol. 2013 Jul 07;2013:916376. (PMID: 27335864)
Parasit Vectors. 2017 Mar 13;10(1):119. (PMID: 28285598)
Vet Med Int. 2020 Aug 6;2020:3146845. (PMID: 32832062)
Pathogens. 2021 Apr 13;10(4):. (PMID: 33924616)
Vet Clin Pathol. 2005 Jun;34(2):85-99. (PMID: 15902658)
Can Vet J. 2012 Mar;53(3):250-6. (PMID: 22942439)
Vet Med Int. 2023 Nov 15;2023:9965095. (PMID: 38023429)
Parasit Vectors. 2022 May 10;15(1):107. (PMID: 35534884)
Front Vet Sci. 2022 Aug 01;9:949372. (PMID: 35978706)
Vet Comp Oncol. 2021 Sep;19(3):482-491. (PMID: 33576562)
Vet J. 2023 Apr;294:105949. (PMID: 36581149)
Vet J. 2008 Jul;177(1):6-7. (PMID: 18294886)
Acta Vet Hung. 2022 Feb 28;:. (PMID: 35258480)
Vet Clin Pathol. 2016 Dec;45(4):552-578. (PMID: 27805725)
J Lab Physicians. 2020 Dec;12(4):239-243. (PMID: 33390672)
PLoS Negl Trop Dis. 2019 Jul 15;13(7):e0007594. (PMID: 31306417)
Acta Trop. 2023 Jan;237:106710. (PMID: 36198329)
Parasit Vectors. 2021 Mar 25;14(1):178. (PMID: 33766113)
Cytopathology. 2016 Oct;27(5):359-68. (PMID: 27146425)
Front Physiol. 2022 Jan 28;12:729191. (PMID: 35153805)
J Feline Med Surg. 2020 Jan;22(1):5-30. (PMID: 31916872)
Vet Parasitol. 2007 Mar 31;144(3-4):242-50. (PMID: 17116368)
Vet Parasitol. 2012 Jun 8;187(1-2):302-6. (PMID: 22285010)
Parasit Vectors. 2021 Apr 21;14(1):217. (PMID: 33883004)
Parasit Vectors. 2015 Jun 04;8:302. (PMID: 26041555)
J Vet Intern Med. 2017 Mar;31(2):457-464. (PMID: 28140480)
Parasit Vectors. 2019 Mar 26;12(1):133. (PMID: 30909952)
Parasit Vectors. 2016 May 10;9(1):247. (PMID: 27160725)
Viruses. 2012 Oct 31;4(11):2684-710. (PMID: 23202500)
Vet Clin Pathol. 2023 Feb;52 Suppl 1:37-49. (PMID: 36740231)
Vet Parasitol Reg Stud Reports. 2020 Apr;20:100387. (PMID: 32448520)
Vet Sci. 2022 Sep 16;9(9):. (PMID: 36136724)
Vet J. 2019 Mar;245:22-28. (PMID: 30819422)
Vet Parasitol. 2017 Dec 15;248:39-47. (PMID: 29173539)
فهرسة مساهمة: Keywords: Acute phase proteins; Cat; Co-infection; Erythrocyte sedimentation rate; FIV; Leishmaniosis
المشرفين على المادة: 0 (Biomarkers)
0 (Antibodies, Viral)
0 (Antibodies, Protozoan)
تواريخ الأحداث: Date Created: 20240731 Date Completed: 20240731 Latest Revision: 20240802
رمز التحديث: 20240802
مُعرف محوري في PubMed: PMC11290220
DOI: 10.1186/s13071-024-06396-1
PMID: 39080701
قاعدة البيانات: MEDLINE
الوصف
تدمد:1756-3305
DOI:10.1186/s13071-024-06396-1