دورية أكاديمية
أعرض في EDS

Concomitant Wilms tumor and autosomal dominant polycystic kidney disease.

التفاصيل البيبلوغرافية
العنوان: Concomitant Wilms tumor and autosomal dominant polycystic kidney disease.
المؤلفون: Fleming AM; Department of Surgery, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.; Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA., Gehle DB; Department of Surgery, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.; Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA., Perrino MR; Division of Cancer Predisposition, Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Graetz DE; Solid Tumor Division, Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Bissler JJ; Department of Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.; Division of Pediatric Nephrology, Department of Pediatrics, University of Tennessee Health Science Center, Memphis, Tennessee, USA., McCarville B; Department of Diagnostic Imaging, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Krasin MJ; Department of Radiation Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Brennan RC; Department of Pediatric Hematology & Oncology, Logan Health, Kalispell, Montana, USA., Zhang J; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Yang W; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Sapkota Y; Department of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Hudson MM; Department of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.; Division of Cancer Survivorship, Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Davidoff AM; Department of Surgery, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Green DM; Division of Cancer Survivorship, Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Murphy AJ; Department of Surgery, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.; Division of Pediatric Surgery, Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
المصدر: Pediatric blood & cancer [Pediatr Blood Cancer] 2024 Oct; Vol. 71 (10), pp. e31230. Date of Electronic Publication: 2024 Jul 31.
نوع المنشور: Journal Article; Case Reports
اللغة: English
بيانات الدورية: Publisher: John Wiley Country of Publication: United States NLM ID: 101186624 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-5017 (Electronic) Linking ISSN: 15455009 NLM ISO Abbreviation: Pediatr Blood Cancer Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Hoboken, N.J. : John Wiley, c 2004-
مواضيع طبية MeSH: Kidney Neoplasms*/pathology , Kidney Neoplasms*/complications , Polycystic Kidney, Autosomal Dominant*/complications , Polycystic Kidney, Autosomal Dominant*/pathology , Wilms Tumor*/pathology , Wilms Tumor*/complications, Child, Preschool ; Female ; Humans ; Male ; Nephrectomy ; Retrospective Studies
مستخلص: Background: Concomitant Wilms tumor (WT) and autosomal dominant polycystic kidney disease (ADPKD) is exceedingly rare, presenting a diagnostic and technical challenge to pediatric surgical oncologists. The simultaneous workup and management of these disease processes are incompletely described.
Procedure: We performed a retrospective analysis of patients treated at our institution with concomitant diagnoses of WT and ADPKD. We also review the literature on the underlying biology and management principles of these conditions.
Results: We present three diverse cases of concomitant unilateral WT and ADPKD who underwent nephrectomy. One patient had preoperative imaging consistent with ADPKD with confirmatory testing postoperatively, one was found to have contralateral renal cysts intraoperatively with confirmatory imaging post nephrectomy, and one was diagnosed in childhood post nephrectomy. All patients are alive at last follow-up, and the patient with longest follow-up has progressed to end-stage kidney failure requiring transplantation and dialysis in adulthood. All patients underwent germline testing and were found to have no cancer predisposition syndrome or pathogenic or likely pathogenic variants for WT.
Conclusion: Concomitant inheritance of ADPKD and development of WT are extremely rare, and manifestations of ADPKD may not present until late childhood or adulthood. ADPKD is not a known predisposing condition for WT. When ADPKD diagnosis is made by family history, imaging, and/or genetic testing before WT diagnosis and treatment, the need for extensive preoperative characterization of cystic kidney lesions in children and increased risk of post-nephrectomy kidney failure warrant further discussion of surgical approach and perioperative management strategies.
(© 2024 Wiley Periodicals LLC.)
References: J Pediatr Surg. 2008 Nov;43(11):e21-3. (PMID: 18970915)
Am J Surg Pathol. 2013 Oct;37(10):1469-89. (PMID: 24025519)
Indian J Pediatr. 2011 Oct;78(10):1290-2. (PMID: 21660403)
Magn Reson Imaging Clin N Am. 2019 May;27(2):279-290. (PMID: 30910098)
Clin Med (Lond). 2009 Jun;9(3):278-83. (PMID: 19634398)
Front Pediatr. 2023 Jan 20;11:1122390. (PMID: 36743884)
J Urol. 1997 Nov;158(5):1926-7. (PMID: 9334639)
J Med Genet. 2020 May 7;:. (PMID: 32381729)
Abdom Radiol (NY). 2022 Jan;47(1):272-287. (PMID: 34623494)
Ann Surg. 2017 Sep;266(3):470-478. (PMID: 28795993)
J Clin Med. 2022 Nov 03;11(21):. (PMID: 36362756)
J Urol. 1989 May;141(5):1151-3. (PMID: 2540350)
Science. 2019 Dec 6;366(6470):1247-1251. (PMID: 31806814)
Pediatr Blood Cancer. 2013 Jun;60(6):994-1000. (PMID: 23255438)
Cancer. 1977 Aug;40(2):789-95. (PMID: 196744)
J Am Soc Nephrol. 1994 May;4(11):1925-6. (PMID: 7919146)
Kidney Int. 2015 Oct;88(4):684-90. (PMID: 26154924)
Magn Reson Imaging Clin N Am. 2013 Nov;21(4):697-715. (PMID: 24183521)
J Clin Oncol. 2020 May 10;38(14):1558-1568. (PMID: 32134700)
Urology. 2009 Sep;74(3):631-4. (PMID: 19616833)
Nat Rev Nephrol. 2019 Apr;15(4):240-251. (PMID: 30705419)
N Engl J Med. 2014 Dec 11;371(24):2255-66. (PMID: 25399733)
Lancet. 2019 Mar 2;393(10174):919-935. (PMID: 30819518)
Front Pediatr. 2024 Mar 21;12:1322142. (PMID: 38577638)
J Urol. 1997 Dec;158(6):2256-9; discussion 2259-60. (PMID: 9366370)
Trends Mol Med. 2023 Apr;29(4):268-281. (PMID: 36805211)
Med Pediatr Oncol. 1993;21(3):169-71. (PMID: 8383277)
Cancer. 2020 Aug 1;126(15):3516-3525. (PMID: 32459384)
J Am Soc Nephrol. 1992 Nov;3(5):1119-23. (PMID: 1482752)
J Ultrasound. 2019 Sep;22(3):381-393. (PMID: 30600488)
J Am Soc Nephrol. 2018 Oct;29(10):2593-2600. (PMID: 30135240)
Ecancermedicalscience. 2022 Feb 17;16:1356. (PMID: 35510137)
Front Oncol. 2020 Sep 04;10:1248. (PMID: 33014769)
Kidney Int. 2002 Jun;61(6):2201-9. (PMID: 12028461)
Br J Surg. 2002 Jul;89(7):845-60. (PMID: 12081733)
Cochrane Database Syst Rev. 2013 Oct 08;(10):CD008944. (PMID: 24101439)
Adv Kidney Dis Health. 2023 May;30(3):209-219. (PMID: 37088523)
Arch Dis Child. 2006 Dec;91(12):995-9. (PMID: 16857697)
Am J Hum Genet. 2016 Jun 2;98(6):1193-1207. (PMID: 27259053)
Pediatr Blood Cancer. 2011 Dec 15;57(7):1210-6. (PMID: 21384541)
Nat Rev Nephrol. 2019 Nov;15(11):713-726. (PMID: 31118499)
Pediatr Blood Cancer. 2016 Sep;63(9):1571-7. (PMID: 27228957)
J Pediatr Surg. 2020 Jan;55(1):126-129. (PMID: 31711743)
Children (Basel). 2018 Sep 24;5(10):. (PMID: 30250006)
Int Urol Nephrol. 2019 Jan;51(1):93-100. (PMID: 30109558)
J Pediatr Urol. 2015 Jun;11(3):113-7. (PMID: 25934353)
J Am Soc Nephrol. 2011 May;22(5):839-48. (PMID: 21493775)
J Ultrasound Med. 2023 Dec;42(12):2873-2881. (PMID: 37676901)
Orphanet J Rare Dis. 2014 Sep 20;9:138. (PMID: 25238977)
Am J Kidney Dis. 2016 May;67(5):792-810. (PMID: 26530876)
Scand J Urol Nephrol. 2009;43(6):476-81. (PMID: 19968582)
Nephrol Dial Transplant. 2017 Aug 01;32(8):1356-1363. (PMID: 27325254)
Mol Genet Genomic Med. 2019 Jul;7(7):e00725. (PMID: 31197971)
J Pathol. 1975 Mar;115(3):175-8. (PMID: 168329)
معلومات مُعتمدة: American Lebanese Syrian Associated Charities; U01-CA195547-1 US National Institutes of Health/National Cancer Institute Cancer Center Support Grant; P30 CA021765 United States CA NCI NIH HHS; U01 CA195547 United States CA NCI NIH HHS; CA21765 US National Institutes of Health/National Cancer Institute Cancer Center Support Grant; U24 CA055727 United States CA NCI NIH HHS
فهرسة مساهمة: Keywords: Wilms tumor; nephroblastoma; polycystic kidney disease
تواريخ الأحداث: Date Created: 20240801 Date Completed: 20240823 Latest Revision: 20240904
رمز التحديث: 20240904
مُعرف محوري في PubMed: PMC11369902
DOI: 10.1002/pbc.31230
PMID: 39085996
قاعدة البيانات: MEDLINE
الوصف
تدمد:1545-5017
DOI:10.1002/pbc.31230