دورية أكاديمية

Screening for atrial fibrillation: the role of CHA 2 DS 2 -VASc and atrial fibrillation burden.

التفاصيل البيبلوغرافية
العنوان: Screening for atrial fibrillation: the role of CHA 2 DS 2 -VASc and atrial fibrillation burden.
المؤلفون: Xing LY; Department of Cardiology, Heart Center, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark., Vad OB; Department of Cardiology, Heart Center, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Engler D; Department of Cardiology, University Heart and Vascular Center Hamburg Eppendorf, Hamburg, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site Hamburg/Kiel/Lübeck, Hamburg, Germany., Svendsen JH; Department of Cardiology, Heart Center, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Diederichsen SZ; Department of Cardiology, Heart Center, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.
المصدر: European heart journal supplements : journal of the European Society of Cardiology [Eur Heart J Suppl] 2024 Jul 31; Vol. 26 (Suppl 4), pp. iv41-iv49. Date of Electronic Publication: 2024 Jul 31 (Print Publication: 2024).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 100886647 Publication Model: eCollection Cited Medium: Print ISSN: 1520-765X (Print) Linking ISSN: 1520765X NLM ISO Abbreviation: Eur Heart J Suppl Subsets: PubMed not MEDLINE
أسماء مطبوعة: Publication: 2005- : Oxford : Oxford University Press
Original Publication: London, U.K. : Saunders, c1999-
مستخلص: Individuals with subclinical atrial fibrillation (AF) face an increased risk of thromboembolic events, which may potentially be mitigated through AF screening and subsequent anticoagulation. However, data from randomized clinical trials (RCTs) indicate a lower stroke risk in subclinical AF compared with the clinical phenotype. This-along with the inherent bleeding risk related to anticoagulation-seems to render the net clinical benefit of AF screening less evident. Further, current guidelines recommend consideration of CHA 2 DS 2 -VASc score and AF episode duration to guide screening and treatment. These recommendations, in general, lack support and seem questionable in view of the limited RCT data. More evidence is warranted to provide insights into the potential benefits of screening and treatment of screen-detected AF in specific population subgroups and AF phenotypes.
Competing Interests: Conflict of interest: L.Y.X., O.B.V., and D.E. have no conflicts of interest to report. J.H.S. reports to be a member of Vital Beats and Medtronic advisory boards and to have received speaker honoraria and research grants from Medtronic outside this work. S.Z.D. reports to be a part-time employee of Vital Beats and advisor at Bristol Myers Squibb/Pfizer, not related to this work.
(© The Author(s) 2024. Published by Oxford University Press on behalf of the European Society of Cardiology.)
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فهرسة مساهمة: Keywords: Anticoagulation; Atrial fibrillation; Screening; Stroke
تواريخ الأحداث: Date Created: 20240805 Latest Revision: 20240806
رمز التحديث: 20240806
مُعرف محوري في PubMed: PMC11292411
DOI: 10.1093/eurheartjsupp/suae078
PMID: 39099574
قاعدة البيانات: MEDLINE
الوصف
تدمد:1520-765X
DOI:10.1093/eurheartjsupp/suae078