دورية أكاديمية
Validation of the Barcelona-MRI predictive model when PI-RADS v2.1 is used with trans-perineal prostate biopsies.
| العنوان: | Validation of the Barcelona-MRI predictive model when PI-RADS v2.1 is used with trans-perineal prostate biopsies. |
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| المؤلفون: | Morote J; Department of Urology, Hospital Univeritari Vall d´Hebron, Barcelona, Spain.; Department of Surgery, Universitat Autònoma de Barcelona, Bellaterra, Spain., Paesano N; Department of Surgery, Universitat Autònoma de Barcelona, Bellaterra, Spain.; Clínica Creu Blanca, Barcelona, Spain., Picola N; Department of Urology, Hospital Universitari de Bellvitge, Hospitalet de Llobregat, Spain., Muñoz-Rodriguez J; Department of Urology, Hospital Universitari Parc Tauli, Sabadell, Spain., Ruiz-Plazas X; Department of Urology, Hospital Universitari Joan XXIII, Tarragona, Spain., Muñoz-Rivero MV; Department of Urology, Hospital Universitari Arnau de Vilanova, Lleida, Spain., Celma A; Department of Urology, Hospital Univeritari Vall d´Hebron, Barcelona, Spain., García-de Manuel G; Department of Urology, Hospital Universitari Josep Trueta, Girona, Spain., Miró B; Statistic Unit, Vall d´Hebron Research Institute, Barcelona, Spain., Servian P; Department of Urology, Hospital Univeritari Germans Trias i Pujol, Badalona, Spain., Abascal JM; Department of Urology, Parc de Salut Mar, Barcelona Spain.; Department of Medicine and Health Sciences, Universitat Pompeu Fabra, Barcelona, Spain. |
| المصدر: | International braz j urol : official journal of the Brazilian Society of Urology [Int Braz J Urol] 2024 Sep-Oct; Vol. 50 (5), pp. 595-604. |
| نوع المنشور: | Journal Article; Validation Study |
| اللغة: | English |
| بيانات الدورية: | Publisher: Brazilian Society of Urology Country of Publication: Brazil NLM ID: 101158091 Publication Model: Print Cited Medium: Internet ISSN: 1677-6119 (Electronic) Linking ISSN: 16775538 NLM ISO Abbreviation: Int Braz J Urol Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Rio de Janerio, RJ, Brazil : Brazilian Society of Urology, [2002]- |
| مواضيع طبية MeSH: | Prostatic Neoplasms*/pathology , Prostatic Neoplasms*/diagnostic imaging , Image-Guided Biopsy*/methods , Multiparametric Magnetic Resonance Imaging*/methods , Prostate*/pathology , Prostate*/diagnostic imaging, Humans ; Male ; Prospective Studies ; Aged ; Middle Aged ; Perineum/diagnostic imaging ; Perineum/pathology ; Predictive Value of Tests ; Reproducibility of Results ; Sensitivity and Specificity ; Magnetic Resonance Imaging/methods |
| مستخلص: | Purpose: To validate the Barcelona magnetic resonance imaging predictive model (BCN-MRI PM) in men with pre-biopsy multiparametric MRI (mpMRI) reported with the Prostate Imaging Reporting and Data System (PI-RADS) v2.1, followed by transrectal and transperineal prostate biopsies. Materials and Methods: Prospective analysis of 3,264 men with PSA >3.0 ng/mL and/or abnormal digital rectal examination who were referred to ten participant centers in the csPCa early detection program of Catalonia (Spain), between 2021 and 2023. MpMRI was reported with the PI-RADS v2.1, and 2- to 4-core MRI-transrectal ultrasound (TRUS) fusion-targeted biopsy of suspected lesions and/or 12-core systematic biopsy were conducted. 2,295 (70.3%) individuals were referred to six centers for transrectal prostate biopsies, while 969 (39.7%) were referred to four centers for transperineal prostate biopsies. CsPCa was classified whenever the International Society of Urologic Pathology grade group was 2 or higher. Results: CsPCa was detected in 41% of transrectal prostate biopsies and in 45.9% of transperineal prostate biopsies (p < 0.016). Both BCN-MRI PM calibration curves were within the ideal correlation between predicted and observed csPCa. Areas under the curve and 95% confidence intervals were 0.847 (0.830-0.857) and 0.830 (0.823-0.855), respectively (p = 0.346). Specificities corresponding to 95% sensitivity were 37.6 and 36.8%, respectively (p = 0.387). The Net benefit of the BCN-MRI PM was similar with both biopsy methods. Conclusions: The BCN-MRI PM has been successfully validated when mpMRI was reported with the PI-RADS v2.1 and prostate biopsies were conducted via the transrectal and transperineal route. Competing Interests: None declared. (Copyright® by the International Brazilian Journal of Urology.) |
| فهرسة مساهمة: | Keywords: Diagnosis; Magnetic Resonance Imaging; Prostatic Neoplasms |
| تواريخ الأحداث: | Date Created: 20240806 Date Completed: 20240806 Latest Revision: 20240806 |
| رمز التحديث: | 20240807 |
| DOI: | 10.1590/S1677-5538.IBJU.2024.0204 |
| PMID: | 39106115 |
| قاعدة البيانات: | MEDLINE |
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