دورية أكاديمية
Meibography health score: a simple grading system for isotretinoin-induced meibography alterations on patients with acne vulgaris.
| العنوان: | Meibography health score: a simple grading system for isotretinoin-induced meibography alterations on patients with acne vulgaris. |
|---|---|
| المؤلفون: | Andrade FMX; Department of Ophthalmology and Visual Sciences, Hospital São Paulo, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil., Hirai F; Department of Ophthalmology and Visual Sciences, Hospital São Paulo, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil., Wakamatsu TH; Department of Ophthalmology and Visual Sciences, Hospital São Paulo, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil., Medina RIS; Department of Dermatology, Hospital São Paulo, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil., Freitas D; Department of Ophthalmology and Visual Sciences, Hospital São Paulo, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil. |
| المصدر: | Arquivos brasileiros de oftalmologia [Arq Bras Oftalmol] 2024 Aug 02; Vol. 88 (1), pp. e20230150. Date of Electronic Publication: 2024 Aug 02 (Print Publication: 2024). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Conselho Brasileiro de Oftalmologia Country of Publication: Brazil NLM ID: 0400645 Publication Model: eCollection Cited Medium: Internet ISSN: 1678-2925 (Electronic) Linking ISSN: 00042749 NLM ISO Abbreviation: Arq Bras Oftalmol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: São Paulo : Conselho Brasileiro de Oftalmologia Original Publication: São Paulo. |
| مواضيع طبية MeSH: | Isotretinoin*/adverse effects , Acne Vulgaris*/drug therapy , Meibomian Glands*/drug effects , Meibomian Glands*/diagnostic imaging , Meibomian Glands*/pathology , Dermatologic Agents*/adverse effects , Observer Variation*, Humans ; Reproducibility of Results ; Severity of Illness Index ; Female ; Male ; Eyelid Diseases/chemically induced ; Eyelid Diseases/diagnostic imaging |
| مستخلص: | Purpose: To develop a simple, subjective, and reliable grading scale for isotretinoin-induced meibography changes. Methods: After analyzing meibography images obtained from systemic isotretinoin users, a grading scale was proposed and named "meibography health score." The score ranged from 1 to 3, with decreasing gland reflectivity and identifiable margins. A total of 11 medical professionals were asked to grade 10 meibography images obtained from isotretinoin users using the proposed scale and were divided into three groups: (A) ophthalmologists with experience with meibography, (B) ophthalmologists with no experience with meibography, and (C) radiologists. The kappa statistic was determined to test interrater reliability. Results: The overall kappa was approximately 0.64. The kappa scores for Groups A, B, and C were 0.78, 0.59, and 0.90, respectively. Grade 2 had the lowest kappa scores (0.62, 0.35, and 0.82 for A, B, and C, respectively) and grade 3 the highest (0.78, 0.90, and 1.0 for A, B and C, respectively). Furthermore, Group C had the highest kappa scores and Group B the lowest. Conclusion: The meibography health score exhibited good interrater reliability, particularly in severe cases. |
| المشرفين على المادة: | EH28UP18IF (Isotretinoin) 0 (Dermatologic Agents) |
| تواريخ الأحداث: | Date Created: 20240807 Date Completed: 20240807 Latest Revision: 20240807 |
| رمز التحديث: | 20240807 |
| DOI: | 10.5935/0004-2749.2023-0150 |
| PMID: | 39109742 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1678-2925 |
|---|---|
| DOI: | 10.5935/0004-2749.2023-0150 |