دورية أكاديمية
أعرض في EDS

Unraveling the complex interplay: immunopathology and immune evasion strategies of alphaviruses with emphasis on neurological implications.

التفاصيل البيبلوغرافية
العنوان: Unraveling the complex interplay: immunopathology and immune evasion strategies of alphaviruses with emphasis on neurological implications.
المؤلفون: de Oliveira Souza R; Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo (USP), São Paulo, Brazil., Duarte Júnior JWB; Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo (USP), São Paulo, Brazil., Della Casa VS; Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo (USP), São Paulo, Brazil., Santoro Rosa D; Department of Microbiology, Immunology and Parasitology, Federal University of São Paulo (UNIFESP), São Paulo, Brazil., Renia L; ASTAR Infectious Diseases Labs (ASTAR ID Labs), Agency for Science, Technology and Research (ASTAR), Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore., Claser C; Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo (USP), São Paulo, Brazil.; Department of Microbiology, Immunology and Parasitology, Federal University of São Paulo (UNIFESP), São Paulo, Brazil.
المصدر: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2024 Aug 15; Vol. 14, pp. 1421571. Date of Electronic Publication: 2024 Aug 15 (Print Publication: 2024).
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Frontiers Media SA Country of Publication: Switzerland NLM ID: 101585359 Publication Model: eCollection Cited Medium: Internet ISSN: 2235-2988 (Electronic) Linking ISSN: 22352988 NLM ISO Abbreviation: Front Cell Infect Microbiol Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Lausanne : Frontiers Media SA
مواضيع طبية MeSH: Immune Evasion* , Alphavirus*/pathogenicity , Alphavirus*/immunology , Alphavirus Infections*/immunology , Alphavirus Infections*/virology , Host-Pathogen Interactions*/immunology , Blood-Brain Barrier*/immunology, Humans ; Animals ; Nervous System Diseases/immunology ; Nervous System Diseases/virology
مستخلص: Arthritogenic alphaviruses pose a significant public health concern due to their ability to cause joint inflammation, with emerging evidence of potential neurological consequences. In this review, we examine the immunopathology and immune evasion strategies employed by these viruses, highlighting their complex mechanisms of pathogenesis and neurological implications. We delve into how these viruses manipulate host immune responses, modulate inflammatory pathways, and potentially establish persistent infections. Further, we explore their ability to breach the blood-brain barrier, triggering neurological complications, and how co-infections exacerbate neurological outcomes. This review synthesizes current research to provide a comprehensive overview of the immunopathological mechanisms driving arthritogenic alphavirus infections and their impact on neurological health. By highlighting knowledge gaps, it underscores the need for research to unravel the complexities of virus-host interactions. This deeper understanding is crucial for developing targeted therapies to address both joint and neurological manifestations of these infections.
Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
(Copyright © 2024 de Oliveira Souza, Duarte Júnior, Della Casa, Santoro Rosa, Renia and Claser.)
References: J Infect Dis. 2009 Aug 15;200(4):516-23. (PMID: 19572805)
Mol Neurobiol. 2024 May;61(5):2881-2903. (PMID: 37946006)
Presse Med. 2006 Nov;35(11 Pt 1):1656-1658. (PMID: 17086120)
Adv Virus Res. 1989;36:255-71. (PMID: 2544083)
J Virol. 2014 Aug;88(15):8213-26. (PMID: 24829346)
Arch Pathol Lab Med. 1996 Feb;120(2):164-72. (PMID: 8712896)
J Neuroimmunol. 2017 Jul 15;308:118-130. (PMID: 28501330)
Nature. 2011 Apr 28;472(7344):481-5. (PMID: 21478870)
An Acad Bras Cienc. 2016 Sep;88(3):1485-99. (PMID: 27627069)
Nat Rev Rheumatol. 2012 May 08;8(7):420-9. (PMID: 22565316)
PLoS Negl Trop Dis. 2014 Jul 17;8(7):e2996. (PMID: 25033077)
J Infect Dis. 1962 Jan-Feb;110:80-97. (PMID: 13899188)
Expert Rev Vaccines. 2012 Sep;11(9):1087-101. (PMID: 23151166)
Trends Microbiol. 2015 Jan;23(1):35-43. (PMID: 25449049)
Adv Exp Med Biol. 2019;1161:169-191. (PMID: 31562630)
Am J Pathol. 2011 Jan;178(1):32-40. (PMID: 21224040)
Microorganisms. 2021 Apr 22;9(5):. (PMID: 33922370)
Sci Transl Med. 2017 Feb 1;9(375):. (PMID: 28148838)
Virus Res. 2013 Nov 6;177(2):179-88. (PMID: 24012515)
J Innate Immun. 2011;3(3):274-9. (PMID: 21411975)
Emerg Infect Dis. 2016 Apr;22(4):750-2. (PMID: 26981875)
J Allergy Clin Immunol. 2015 Apr;135(4):846-855. (PMID: 25843597)
J Neuroimmunol. 2002 Jun;127(1-2):106-14. (PMID: 12044981)
J Infect Dis. 2008 Jun 1;197(11):1585-93. (PMID: 18433328)
Neurocrit Care. 2017 Dec;27(3):447-457. (PMID: 28741102)
J Clin Virol. 2015 Aug;69:27-9. (PMID: 26209372)
Aust N Z J Med. 1984 Aug;14(4):505-6. (PMID: 6097207)
Viruses. 2021 Jul 05;13(7):. (PMID: 34372513)
mBio. 2022 Apr 26;13(2):e0028922. (PMID: 35254128)
J Med Virol. 2014 Aug;86(8):1393-401. (PMID: 24523146)
J Virol. 2005 Jun;79(12):7597-608. (PMID: 15919912)
PLoS Negl Trop Dis. 2015 Oct 23;9(10):e0004104. (PMID: 26496497)
Epidemiol Infect. 2002 Oct;129(2):335-45. (PMID: 12403109)
J Microbiol Biotechnol. 2019 Nov 28;29(11):1852-1859. (PMID: 31635445)
Adv Virus Res. 2020;107:315-382. (PMID: 32711733)
Viruses. 2019 Nov 13;11(11):. (PMID: 31766138)
PLoS One. 2013 Dec 23;8(12):e84695. (PMID: 24376836)
EMBO Mol Med. 2012 Apr;4(4):330-43. (PMID: 22389221)
Microbiol Rev. 1994 Sep;58(3):491-562. (PMID: 7968923)
J Exp Med. 2010 Feb 15;207(2):429-42. (PMID: 20123960)
Viruses. 2016 Jun 11;8(6):. (PMID: 27294951)
Antiviral Res. 2023 Jan;209:105476. (PMID: 36436722)
Viruses. 2019 Aug 29;11(9):. (PMID: 31470617)
J Gen Virol. 2009 Aug;90(Pt 8):1836-1847. (PMID: 19369408)
J Assoc Physicians India. 2011 Feb;59:83-6. (PMID: 21751641)
Nat Med. 2004 Dec;10(12):1366-73. (PMID: 15558055)
Virology. 1999 Apr 25;257(1):106-18. (PMID: 10208925)
Neuroimmunomodulation. 2014;21(6):338-46. (PMID: 24776821)
J Virol. 2024 Jan 23;98(1):e0110223. (PMID: 38169294)
J Virol. 2011 Jan;85(1):606-20. (PMID: 20962078)
J Virol. 2010 Aug;84(16):8021-32. (PMID: 20519386)
Proc Natl Acad Sci U S A. 2007 Oct 23;104(43):17140-5. (PMID: 17939996)
NPJ Parkinsons Dis. 2019 Sep 13;5:20. (PMID: 31531390)
Trends Biochem Sci. 2022 Nov;47(11):978-988. (PMID: 35618579)
J Virol. 2006 Jun;80(12):5686-96. (PMID: 16731907)
PLoS Pathog. 2024 Mar 14;20(3):e1011794. (PMID: 38483968)
Lancet Infect Dis. 2017 Apr;17(4):e107-e117. (PMID: 28159534)
Elife. 2018 Jun 19;7:. (PMID: 29914621)
BMC Infect Dis. 2009 Dec 10;9:200. (PMID: 20003320)
Nat Rev Immunol. 2016 Sep;16(9):566-80. (PMID: 27455396)
Pathogens. 2015 Sep 16;4(3):662-81. (PMID: 26389957)
J Virol. 1998 Jun;72(6):5146-53. (PMID: 9573286)
J Neurovirol. 2016 Apr;22(2):140-8. (PMID: 26419894)
Mediators Inflamm. 2021 May 31;2021:9999146. (PMID: 34158806)
BMC Genomics. 2008 Jun 16;9:289. (PMID: 18558011)
Am J Trop Med Hyg. 2018 May;98(5):1472-1477. (PMID: 29557336)
Immunology. 2018 Dec;155(4):499-504. (PMID: 30099739)
PLoS Pathog. 2008 Feb 8;4(2):e29. (PMID: 18282093)
Nat Rev Immunol. 2021 Sep;21(9):548-569. (PMID: 33833439)
J Virol. 2003 May;77(9):5333-8. (PMID: 12692235)
J Virol. 2009 Oct;83(19):10036-47. (PMID: 19641001)
Science. 1979 Mar 16;203(4385):1127-9. (PMID: 424742)
N Engl J Med. 1997 Jun 26;336(26):1867-74. (PMID: 9197215)
Lancet Infect Dis. 2021 May;21(5):e123-e133. (PMID: 33160445)
J Infect Dis. 1990 Apr;161(4):685-91. (PMID: 2156944)
Nat Rev Immunol. 2002 Sep;2(9):675-87. (PMID: 12209136)
J Virol. 2014 Jun;88(12):6862-72. (PMID: 24696480)
PLoS One. 2007 Jun 13;2(6):e527. (PMID: 17565380)
PLoS Pathog. 2012;8(3):e1002586. (PMID: 22457620)
J Neuroinflammation. 2020 Aug 10;17(1):233. (PMID: 32778106)
J Virol. 2008 Nov;82(22):11263-72. (PMID: 18787004)
PLoS One. 2009 Oct 28;4(10):e7603. (PMID: 19893613)
Euro Surveill. 2016 Jun 2;21(22):. (PMID: 27277216)
Emerg Infect Dis. 2019 Feb;25(2):311-315. (PMID: 30666934)
PLoS Med. 2008 Mar 18;5(3):e60. (PMID: 18351797)
Virology. 2012 Apr 10;425(2):103-12. (PMID: 22305131)
J Assoc Physicians India. 2012 Apr;60:68-70. (PMID: 23029750)
Cell. 2015 Nov 19;163(5):1095-1107. (PMID: 26553503)
J Gen Virol. 2015 Feb;96(Pt 2):294-310. (PMID: 25351727)
Viral Immunol. 2003;16(4):447-60. (PMID: 14733733)
Epidemiol Infect. 2009 Apr;137(4):534-41. (PMID: 18694529)
Virology. 1996 Oct 1;224(1):73-83. (PMID: 8862401)
Methods Mol Biol. 2011;665:17-38. (PMID: 21116793)
Nat Rev Microbiol. 2010 Jul;8(7):491-500. (PMID: 20551973)
Am J Trop Med Hyg. 2013 Jun;88(6):1170-9. (PMID: 23568285)
PLoS Pathog. 2011 Sep;7(9):e1002268. (PMID: 21966274)
J Infect Dis. 2012 Apr 1;205(7):1147-54. (PMID: 22389226)
Signal Transduct Target Ther. 2021 Nov 26;6(1):402. (PMID: 34824210)
Trends Microbiol. 2015 Jan;23(1):55-63. (PMID: 25456015)
Nat Rev Immunol. 2015 Aug;15(8):471-85. (PMID: 26160613)
Virol J. 2013 Jan 28;10:36. (PMID: 23356742)
Indian J Med Res. 1968 Jun;56(6):802-11. (PMID: 4971384)
Virol J. 2015 Sep 30;12:154. (PMID: 26423229)
J Virol. 2007 May;81(10):5132-43. (PMID: 17314163)
Cell Rep. 2015 Dec 22;13(11):2553-2564. (PMID: 26686638)
PLoS Pathog. 2020 May 4;16(5):e1008517. (PMID: 32365139)
Proc Natl Acad Sci U S A. 2014 Nov 11;111(45):16053-8. (PMID: 25362048)
J Interferon Cytokine Res. 2011 Jan;31(1):5-11. (PMID: 21226606)
J Infect Dis. 2011 Jul 1;204(1):115-23. (PMID: 21628665)
Biomed Res Int. 2013;2013:973516. (PMID: 24069610)
J Virol. 2008 Nov;82(21):10634-46. (PMID: 18768986)
Virus Res. 2014 Aug 30;189:194-205. (PMID: 24905288)
J Exp Med. 2023 Jan 2;220(1):. (PMID: 36315050)
Am J Trop Med Hyg. 2008 Jul;79(1):133-9. (PMID: 18606777)
Viruses. 2021 Mar 11;13(3):. (PMID: 33799906)
Front Immunol. 2016 Dec 19;7:609. (PMID: 28066419)
Emerg Microbes Infect. 2019;8(1):1003-1016. (PMID: 31282298)
Am J Pathol. 1973 Nov;73(2):425-42. (PMID: 4796626)
J Interferon Cytokine Res. 2007 Feb;27(2):103-9. (PMID: 17316137)
Int J Dermatol. 2011 Jan;50(1):61-9. (PMID: 21182504)
J Clin Invest. 2010 Mar;120(3):894-906. (PMID: 20179353)
Vaccine. 2012 Jun 29;30(31):4638-43. (PMID: 22583812)
Front Immunol. 2022 Sep 12;13:1005586. (PMID: 36172361)
Immunity. 2012 Apr 20;36(4):503-14. (PMID: 22520844)
Viruses. 2019 Jan 31;11(2):. (PMID: 30709036)
J Virol. 2018 Aug 16;92(17):. (PMID: 29925658)
Cell. 2024 Feb 15;187(4):813-813.e1. (PMID: 38364787)
J Gen Virol. 2009 Aug;90(Pt 8):1848-1858. (PMID: 19403754)
J Virol. 2019 Dec 12;94(1):. (PMID: 31619554)
Clin Microbiol Rev. 2001 Oct;14(4):909-32, table of contents. (PMID: 11585790)
New Microbes New Infect. 2015 Apr 15;7:23-5. (PMID: 26106482)
J Neural Transm (Vienna). 2024 Jan 23;:. (PMID: 38261034)
J Virol. 2012 May;86(9):5055-66. (PMID: 22345447)
J Clin Invest. 2007 Oct;117(10):3059-66. (PMID: 17909632)
Trends Immunol. 2003 Apr;24(4):165-8. (PMID: 12697441)
Vet Microbiol. 2010 Jan 27;140(3-4):281-6. (PMID: 19775836)
Virology. 2009 Mar 15;385(2):425-33. (PMID: 19135695)
Proc Natl Acad Sci U S A. 2007 Jan 23;104(4):1371-6. (PMID: 17227866)
Annu Rev Immunol. 2022 Apr 26;40:615-649. (PMID: 35134315)
Virol J. 2014 Oct 21;11:183. (PMID: 25330992)
J Exp Med. 2019 Oct 7;216(10):2282-2301. (PMID: 31337735)
Am J Trop Med Hyg. 1998 Jan;58(1):35-40. (PMID: 9452289)
Immunology. 2017 Dec;152(4):545-555. (PMID: 28744856)
J Neuroimmunol. 2016 Jun 15;295-296:60-7. (PMID: 27235350)
Immunol Rev. 2008 Oct;225:27-45. (PMID: 18837774)
Trans R Soc Trop Med Hyg. 2010 Jun;104(6):392-9. (PMID: 20171708)
J Virol. 2020 Jan 17;94(3):. (PMID: 31694940)
Cells. 2021 Dec 12;10(12):. (PMID: 34944018)
Pathog Glob Health. 2017 Sep;111(6):271-275. (PMID: 28829253)
Nat Rev Microbiol. 2023 Jun;21(6):396-407. (PMID: 36474012)
Virology. 2010 Feb 5;397(1):130-8. (PMID: 19922973)
Immunity. 2019 Apr 16;50(4):907-923. (PMID: 30995506)
J Virol. 2013 Sep;87(18):10394-400. (PMID: 23864632)
J Virol. 2013 May;87(10):5697-706. (PMID: 23487448)
Neurology. 1977 Nov;27(11):1095-6. (PMID: 563006)
J Virol. 2013 Dec;87(24):13878-88. (PMID: 24131709)
PLoS One. 2009;4(1):e4261. (PMID: 19156204)
J Virol. 2010 Oct;84(20):10877-87. (PMID: 20686047)
Rev Bras Reumatol. 2010 Nov-Dec;50(6):695-702. (PMID: 21243308)
Vet Pathol. 1998 Sep;35(5):386-97. (PMID: 9754544)
J Virol. 2016 May 27;90(12):5785-96. (PMID: 27053560)
Vector Borne Zoonotic Dis. 2015 Apr;15(4):241-9. (PMID: 25897810)
PLoS Negl Trop Dis. 2014 Dec 04;8(12):e3354. (PMID: 25474568)
J Virol. 2011 Oct;85(20):10682-90. (PMID: 21849461)
Infect Immun. 1970 Nov;2(5):533-42. (PMID: 16557874)
Rev Med Virol. 2018 May;28(3):e1978. (PMID: 29671914)
Viruses. 2017 Jun 27;9(7):. (PMID: 28654007)
Indian J Med Res. 1965 Jul;53(7):610-3. (PMID: 5827506)
J Clin Virol. 2009 Oct;46(2):145-9. (PMID: 19640780)
Emerg Infect Dis. 2009 Nov;15(11):1830-2. (PMID: 19891877)
Virology. 1992 Aug;189(2):462-73. (PMID: 1386484)
Open Rheumatol J. 2016 Nov 30;10:129-140. (PMID: 28077980)
J Virol. 2006 Jan;80(2):737-49. (PMID: 16378976)
J Virol. 2000 Dec;74(24):11849-57. (PMID: 11090185)
Annu Rev Virol. 2019 Sep 29;6(1):567-584. (PMID: 31283436)
Front Neurosci. 2015 Oct 27;9:390. (PMID: 26578857)
Virology. 2009 Feb 5;384(1):216-22. (PMID: 19056102)
Nat Microbiol. 2023 Sep;8(9):1653-1667. (PMID: 37591996)
J Immunol. 2010 May 15;184(10):5903-13. (PMID: 20404274)
Cell Tissue Res. 2012 Aug;349(2):589-603. (PMID: 22584508)
J Virol. 2000 Apr;74(7):3366-78. (PMID: 10708454)
Am J Forensic Med Pathol. 2020 Mar;41(1):48-51. (PMID: 31977345)
Mamm Genome. 2018 Aug;29(7-8):408-424. (PMID: 30151711)
Int J Infect Dis. 2016 Oct;51:85-88. (PMID: 27619845)
J Virol. 2012 Oct;86(19):10675-85. (PMID: 22837203)
Curr Top Microbiol Immunol. 2005;289:57-77. (PMID: 15791951)
Nature. 2011 Apr 14;472(7342):217-20. (PMID: 21451523)
Medicine (Baltimore). 2007 May;86(3):123-137. (PMID: 17505252)
Antibodies (Basel). 2018 Dec 15;7(4):. (PMID: 31544894)
Cell. 2020 Aug 20;182(4):901-918.e18. (PMID: 32668198)
PLoS Pathog. 2007 Jun;3(6):e89. (PMID: 17604450)
Cell Stem Cell. 2016 Nov 3;19(5):663-671. (PMID: 27524440)
Trends Immunol. 2007 Jun;28(6):252-9. (PMID: 17466596)
Viruses. 2021 Oct 20;13(11):. (PMID: 34834923)
J Virol. 2007 Mar;81(5):2472-84. (PMID: 17108023)
J Glob Infect Dis. 2011 Jul;3(3):221-6. (PMID: 21887052)
Future Virol. 2011;6(6):721-740. (PMID: 21765860)
J Virol. 2000 Oct;74(19):9294-9. (PMID: 10982376)
J Virol. 2012 Dec;86(23):13005-15. (PMID: 23015702)
PLoS Negl Trop Dis. 2019 May 3;13(5):e0007375. (PMID: 31050676)
PLoS Pathog. 2020 Oct 15;16(10):e1008999. (PMID: 33057424)
J Clin Virol. 2018 Jun;103:16-18. (PMID: 29604514)
Curr Opin Virol. 2017 Apr;23:30-34. (PMID: 28288385)
J Gen Virol. 2021 Aug;102(8):. (PMID: 34435944)
mBio. 2012 Dec 11;3(6):. (PMID: 23232716)
PLoS Negl Trop Dis. 2021 Jun 9;15(6):e0009427. (PMID: 34106915)
Virus Res. 2018 Sep 2;256:166-173. (PMID: 30145137)
J Virol. 2015 Jan;89(1):581-93. (PMID: 25339772)
Am J Trop Med Hyg. 1969 Nov;18(6):954-71. (PMID: 5355242)
J Virol. 2002 Jan;76(1):392-6. (PMID: 11739703)
Emerg Infect Dis. 2009 Mar;15(3):495-6. (PMID: 19239775)
PLoS Pathog. 2022 Feb 10;18(2):e1010185. (PMID: 35143591)
J Virol. 2009 Oct;83(20):10571-81. (PMID: 19656875)
PLoS Pathog. 2019 Sep 3;15(9):e1007934. (PMID: 31479495)
Am J Pathol. 2005 Jan;166(1):159-71. (PMID: 15632009)
Cell Host Microbe. 2024 Apr 10;32(4):606-622.e8. (PMID: 38479396)
Arch Ophthalmol. 2007 Oct;125(10):1381-6. (PMID: 17923547)
J Virol. 2020 Apr 16;94(9):. (PMID: 32102875)
Cell. 2020 Dec 23;183(7):1884-1900.e23. (PMID: 33301709)
Curr Opin Virol. 2018 Feb;28:53-60. (PMID: 29175515)
Comp Med. 2018 Oct 1;68(5):380-395. (PMID: 30282570)
J Travel Med. 2023 Jun 23;30(4):. (PMID: 37171132)
J Infect Dis. 2011 Jan 15;203(2):149-57. (PMID: 21288813)
J Immunol. 2013 Jan 1;190(1):259-69. (PMID: 23209328)
Virol J. 2017 Jul 20;14(1):135. (PMID: 28728590)
Viruses. 2019 Mar 22;11(3):. (PMID: 30909385)
J Virol. 2015 Aug;89(15):7955-69. (PMID: 25995257)
Front Microbiol. 2019 Oct 01;10:2246. (PMID: 31632368)
PLoS One. 2013;8(1):e53462. (PMID: 23301074)
J Infect Dis. 2000 Jan;181(1):27-34. (PMID: 10608747)
Virology. 1995 Apr 20;208(2):662-71. (PMID: 7747437)
Indian J Med Res. 1965 Aug;53(8):729-44. (PMID: 5830407)
Adv Anat Embryol Cell Biol. 2003;172:III-XII, 1-122, back cover. (PMID: 12901335)
Sci Rep. 2016 May 16;6:26097. (PMID: 27180811)
Brain Commun. 2023 Mar 25;5(3):fcad086. (PMID: 37168733)
J Immunol. 2010 May 15;184(10):5914-27. (PMID: 20404278)
Virology. 2018 Feb;515:250-260. (PMID: 29324290)
Med J Malaysia. 2010 Mar;65(1):83-4. (PMID: 21265260)
Virology. 2009 Dec 5;395(1):121-32. (PMID: 19782381)
BMC Infect Dis. 2017 Apr 26;17(1):309. (PMID: 28446152)
Viruses. 2021 Feb 27;13(3):. (PMID: 33673546)
Sci Transl Med. 2017 Feb 1;9(375):. (PMID: 28148840)
Front Aging Neurosci. 2024 Apr 12;16:1347987. (PMID: 38681666)
Microbes Infect. 2009 Dec;11(14-15):1206-18. (PMID: 19835977)
J Virol. 2018 Nov 12;92(23):. (PMID: 30232189)
PLoS Pathog. 2013;9(4):e1003312. (PMID: 23637602)
Nat Rev Microbiol. 2013 Feb;11(2):115-28. (PMID: 23321534)
Nucleic Acids Res. 2018 Apr 20;46(7):3657-3670. (PMID: 29361131)
Arthritis Rheumatol. 2015 May;67(5):1214-1220. (PMID: 25605621)
فهرسة مساهمة: Keywords: alphavirus; chikungunya; coinfection; immune evasion; immunopathology; mayaro; mouse; nervous system
تواريخ الأحداث: Date Created: 20240830 Date Completed: 20240830 Latest Revision: 20240903
رمز التحديث: 20240903
مُعرف محوري في PubMed: PMC11358129
DOI: 10.3389/fcimb.2024.1421571
PMID: 39211797
قاعدة البيانات: MEDLINE
الوصف
تدمد:2235-2988
DOI:10.3389/fcimb.2024.1421571